Results 81 to 90 of about 111,828 (202)

Spectrophotometric analysis of thrombolytic activity: SATA assay [PDF]

open access: yes, 2017
Introduction: Measurement of thrombolytic activity i.e. clot lysis is crucial for research and development of novel thrombolytics. It is also a key factor in assessment of the effectiveness of conventionally used thrombolytic agents in the clinic, which ...
Entekhabi, Nazila   +5 more
core   +2 more sources

Plasminogen activator inhibitor-1 in cancer research

open access: yesBiomedicine & Pharmacotherapy, 2018
[Despite as a major inhibitor of urokinase (uPA), paradoxically,] Plasminogen activator inhibitor-1 (PAI-1) has been validated to be highly expressed in various types of tumor biopsy tissues or plasma compared with controls based on huge clinical data bases analysis, more importantly, PAI-1 alone or in conjunction with uPA have been identified as ...
Sijing, Li   +5 more
openaire   +2 more sources

Plasminogen activator inhibitor-1, free fatty acids, and insulin resistance in patients with myocardial infarction

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2013
Olga Gruzdeva, Evgenya Uchasova, Yulia Dyleva, Ekaterina Belik, Ekaterina Shurygina, Olga Barbarash Research Institute for Complex Issues of Cardiovascular Diseases under the Siberian Branch of the Russian Academy of Medical Sciences, Kemerovo, Russian ...
Gruzdeva O   +5 more
doaj  

Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines. [PDF]

open access: yes, 2019
BACKGROUND:Astrocytes contribute to the crosstalk that generates chronic neuro-inflammation in neurological diseases; however, compared with microglia, astrocytes respond to a more limited continuum of innate immune system stimulants.
Azmoon, Pardis   +8 more
core   +1 more source

Corrigendum: Urokinase-type plasminogen activator and plasminogen activator inhibitor-1 complex as a serum biomarker for COVID-19 [PDF]

open access: yesFrontiers in Immunology
Tetiana Yatsenko   +12 more
doaj   +2 more sources

The transcriptional regulation of maspin : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2004
Maspin (mammary serine protease inhibitor) is a tumour suppressing member of the serpin superfamily. Maspin is expressed in normal breast and prostate cells, but reportedly down regulated during progression of cancer in these tissues.
Hollings, Andrew
core  

Pleiotropic functions of plasminogen activator inhibitor-1 [PDF]

open access: yesJournal of Thrombosis and Haemostasis, 2005
Plasminogen activator inhibitor-1 (PAI-1), a 45-kDa serine proteinase inhibitor with reactive site peptide bond Arg345-Met346, is the main physiological plasminogen activator inhibitor. It occurs in human plasma at an antigen concentration of about 20 ng mL(-1).
openaire   +2 more sources

How periodontal disease may contribute to cardiovascular disease [PDF]

open access: yes, 2000
No abstract ...
Kinane, D.F., Lowe, G.D.O.
core   +1 more source

Identification of a novel regulatory mechanism for the disease associated protein, uPAR [PDF]

open access: yes, 2014
Expression quantitative trait loci (eQTLs), as determined through a series of statistical association studies collectively known as genome-wide association (GWA) studies, have provided us with a hypothesis free approach for the investigation into ...
Hall, Ian P.   +2 more
core  

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