Results 141 to 150 of about 75,068 (195)

SERPINE1 Alternative Polyadenylation Influences Gastric Cancer Prognosis via N6‐Methyladenosine Modification

Cancer Science, Volume 117, Issue 11, Page 3132-3145, November 2026.
Multi‐omics integration of the transcriptomic APA landscape and m6A modifications identifies key prognostic genes. Their biological functions and molecular mechanisms in promoting tumor progression are comprehensively validated through in vitro assays. ABSTRACT Alternative polyadenylation (APA) and N6‐methyladenosine (m6A) methylation are critical post‐
Zhuoyi Wu, Ruyun Xu, Ju Fang, Bing Liu, Cao Zhang, Shangxin Zhang, Jing Ni   +6 more
wiley   +1 more source

Rather a versatile multi-tool than a sword: an integral role of the plasminogen system in health and disease. [PDF]

Front Immunol
Skrabana R, Castven M, Tomková M, Sedlák E, Babulic P, Jakubcova M, Moskalets T, Leksa V.   +7 more
europepmc   +1 more source

Recent advances in polyendocrine metabolic ovarian syndrome, formerly polycystic ovary syndrome, with emphasis on endocrine and metabolic dysfunction and cardiovascular risk

Journal of Internal Medicine, Volume 300, Issue 5, Page 590-609, November 2026.
Abstract Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome, affects 10%–13% of women of reproductive age and remains underdiagnosed despite its substantial health burden. The introduction of the new PMOS nomenclature in 2026 reflects a fundamental shift in understanding the condition as a lifelong endocrine ...
Maria Forslund, Johanna Melin, Anju E. Joham, Terhi T. Piltonen, D. Aled Rees, Helena J. Teede   +5 more
wiley   +1 more source

Dynamic alterations of thrombotic molecular markers in acute ischemic stroke patients after intravenous thrombolysis: a prospective cohort study. [PDF]

BMC Neurol
Sun W, Xie S, Liu F, Xie Y, Zhu Y, Wu P, Zhu J, Liu X.   +7 more
europepmc   +1 more source

From Dysbiosis to Disease: How Vaginal Microbiota Shape Group B Streptococcus Pathogenesis

ChemBioChem, Volume 27, Issue 20, 28 October 2026.
Lactobacillus crispatus plays a critical role in the vaginal microbiome. Limiting glucose shifts metabolism toward HMO consumption and amino acid metabolism. These actions enable alkali production and competition. Homeostasis, characterized by dense Lactobacilli colonization and suppression of pathogens, provides resistance to dysbiosis.
Julie A. Talbert, Steven D. Townsend
wiley   +1 more source

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

Abnormal lipid profiles are associated with markers of impaired fibrinolysis in patients with cirrhosis. [PDF]

Res Pract Thromb Haemost
Elvers FL, Adelmeijer J, Stamouli M, Bernal W, Patel VC, Lisman T.   +5 more
europepmc   +1 more source

Influence of Endoplasmic Reticulum Stress on Urokinase Plasminogen Activation. [PDF]

Biomolecules
Culej Bošnjak D, Janjić D, Korać P, Antica M, Matulić M.   +4 more
europepmc   +1 more source

Proteomics-Based Soluble Urokinase Plasminogen Activator Receptor Levels Are Associated With Adverse Cardiovascular Outcomes in the General Population: Insights From the UK Biobank. [PDF]

J Am Heart Assoc
Sakr SM, Medina-Inojosa JR, Liu C, Chuckaree ID, Agusala V, Lodhi R, Mecklai Z, Owais M, Al Kasem M, Hritani W, Hasan M, Hayek S, Sun YV, Quyyumi AA.   +13 more
europepmc   +1 more source