Results 161 to 170 of about 3,326,153 (390)

The Biomaterial and Blood Clot Complex: A Crucial Early Environment for Osteo‐Coagulo‐Immunomodulation and the Advancement of Bone Biomaterials

open access: yesSmall Structures, EarlyView.
Various properties of bone biomaterials can modulate components of the blood clot (including the fibrin network, red blood cells, platelets, and the complement system) in vivo implantation, leading to the formation of a biomaterial–blood clot complex (BBCC) significantly impacting subsequent osteoimmunomodulation.
Zongpu Han   +11 more
wiley   +1 more source

Serine‐proteases as plasminogen activators in terms of fibrinolysis

open access: yesThe Journal of pharmacy and pharmacology, 2012
M. Flemmig, M. Melzig
semanticscholar   +1 more source

Identification of Senomorphic miRNAs in Embryonic Progenitor and Adult Stem Cell‐Derived Extracellular Vesicles

open access: yesAging Cell, EarlyView.
A senomorphic miRNA cocktail (E5), consisting of miR‐181a‐5p, miR‐92a‐3p, miR‐21‐5p, and miR‐186‐5p, was identified from a pool of miRNAs enriched in extracellular vesicles (EVs) derived from multiple functional human stem cell types. E5 reduces senescence and SASP markers both in cell culture and in aged mice.
Tianpeng Zhang   +11 more
wiley   +1 more source

Reducing HuD Levels Alleviates Alzheimer's Disease Pathology in 5xFAD Mice

open access: yesAging Cell, EarlyView.
The effect of ablating expression of the RNA‐binding protein HuD (ELAVL4) in neurons was evaluated in the Alzheimer's mouse model 5xFAD. We found that conditional removal of HuD resulted in diminished Aβ plaque formation and reduced AD‐associated hyperactivity in 5xFAD/HuDcKO mice relative to 5xFAD mice.
Eunbyul Ji   +7 more
wiley   +1 more source

Plasminogen Activator Inhibitor-1 Is a Marker and a Mediator of Senescence.

open access: yesArteriosclerosis, Thrombosis and Vascular Biology, 2017
D. Vaughan   +4 more
semanticscholar   +1 more source

Quercetin Reduces Vascular Senescence and Inflammation in Symptomatic Male but Not Female Coronary Artery Disease Patients

open access: yesAging Cell, EarlyView.
In male patients undergoing CABG surgery, pretreatment with quercetin suppressed inflammaging and its associated inflammation, leading to improved endothelium‐dependent relaxation (measured ex vivo) and reducing new onset of post‐operative atrial fibrillation.
Pauline Mury   +19 more
wiley   +1 more source

Immunomodulatory effects of plasminogen activators on hepatic fibrogenesis

open access: yesClinical and Experimental Immunology, 2008
A. Higazi   +8 more
semanticscholar   +1 more source

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