Results 41 to 50 of about 37,152 (268)

Kidney injury in patients with heart failure‐related cardiogenic shock: Results from an international, multicentre cohort study

open access: yesEuropean Journal of Heart Failure, EarlyView.
Kidney injury in heart failure‐related cardiogenic shock. AKI, acute kidney injury; CI, confidence interval; eCPR, extracorporeal cardiopulmonary resuscitation; eGFR, estimated glomerular filtration rate; HR, hazard ratio; OR, odds ratio; VA‐ECMO, veno‐arterial extracorporeal membrane oxygenation.
Jonas Sundermeyer   +41 more
wiley   +1 more source

Tissue Plasminogen Activator in Psoriasis

open access: yesJournal of Investigative Dermatology, 1990
Elevated levels of the serine proteinase plasminogen activator are observed in psoriatic lesions. In contrast to normal epidermis, lesional psoriatic epidermis contains primarily tissue type plasminogen activator (tPA) activity and much lower levels of urokinase type plasminogen activator (uPA) activity.
Gerald S. Lazarus   +7 more
openaire   +4 more sources

Noncontact Monitoring and AI‐Driven Stroke Prediction: National Center for Neurological Disorders‐Based Approach Using Smart Beds

open access: yesHealth Care Science, EarlyView.
The burden of stroke is extremely heavy. Current prehospital tools are not suitable for identifying stroke while a patient is asleep. This study successfully identified strokes by combining three types of easily accessible temporal and static features in hospitals.
Lan Lan   +6 more
wiley   +1 more source

Enhanced Expression of Plasminogen Activators and Inhibitor in the Healing of Tympanic Membrane Perforation in Rats. [PDF]

open access: yesJ Assoc Res Otolaryngol, 2023
Makuszewska M   +5 more
europepmc   +1 more source

Research progress of neurovascular units involved in ischemic stroke

open access: yesIbrain, EarlyView.
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang   +4 more
wiley   +1 more source

Evaluating Tranexamic Acid Dosing Strategies for Postpartum Hemorrhage: A Population Pharmacokinetic Approach in Pregnant Individuals

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Tranexamic acid (TXA) is used for the treatment and occasionally prevention of postpartum hemorrhage (PPH); however, questions still remain regarding dosing regimen optimization. This study evaluated TXA pharmacokinetic (PK) data from four clinical trials (NCT: 04274335, 03287336, 00872469, and 02797119) conducted in pregnant participants ...
Allison Dunn   +12 more
wiley   +1 more source

Adsorption of Plasminogen Activator to Fibrin. [PDF]

open access: bronze, 1958
Mogens Lassen   +3 more
openalex   +1 more source

Four Pharmacogenomic Variants Strongly Linked to Corticosteroid‐Induced Avascular Necrosis in Children with Cancer

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Corticosteroids are effective anti‐cancer agents for treating hematologic malignancies in children. However, avascular necrosis (AVN) is a common and debilitating adverse effect, leading to bone death and impacting long‐term quality of life. This study aimed to uncover the genetic factors contributing to corticosteroid‐induced AVN in a well ...
Miguel Cordova‐Delgado   +9 more
wiley   +1 more source

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