Results 51 to 60 of about 13,552 (164)

Efforts to reduce the door-to-needle time of thrombolysis in acute ischemic stroke: Video-assisted therapeutic risk communication

Journal of the Formosan Medical Association, 2014
Explaining the risks and benefits of recombinant tissue-plasminogen activator (rtPA) to eligible patients with acute ischemic stroke (AIS) within a few minutes is important but difficult.
Cheng-Yang Hsieh, Wei-Fen Chen, Chih-Hung Chen, Chih-Yuan Wang, Chien-Jung Chen, Edward Chia-Cheng Lai, Tsang-Shan Chen   +6 more
doaj   +1 more source

Plasmin: indigenous milk proteinase

Mljekarstvo, 2002
The most important characteristic of plasmin, as significant indigenous milk proteinase, its concentration, concentration measuring procedure and activity of plasmin are described.
Samir Kalit, Jasmina Lukač Havranek, Vlatka Čubrić Ćurik   +2 more
doaj  

Expression of the plasminogen system in the physiological mouse ovary and in the pathological polycystic ovary syndrome (PCOS) state

Reproductive Biology and Endocrinology, 2019
Background The fibrinolytic system and its inhibitors play a number of roles, apart from their function in blood haemostasis and thrombosis, namely in ovarian folliculogenesis and in ovulation.
Genia F. Burchall, Dodie S. Pouniotis, Helena J. Teede, Sanjeeva Ranasinha, Kirsty A. Walters, Terrence J. Piva   +5 more
doaj   +1 more source

Tissue Plasminogen Activator in Psoriasis

Journal of Investigative Dermatology, 1990
Elevated levels of the serine proteinase plasminogen activator are observed in psoriatic lesions. In contrast to normal epidermis, lesional psoriatic epidermis contains primarily tissue type plasminogen activator (tPA) activity and much lower levels of urokinase type plasminogen activator (uPA) activity.
Jensen, P. J., Baird, J., Belin, Dominique, Vassalli, Jean-Dominique, Busso, N., Gubler, P., Lazarus, G. S.   +6 more
openaire   +3 more sources

THE LEVELS OF PLASMINOGEN AND INHIBITOR OF PLASMINOGEN ACTIVATORS OF TYPE 1 IN ANTIPHOSPHOLIPID SYNDROME

Терапевтический архив, 2012
Aim. To estimate the levels of of plasminogen (Pg) and inhibitor of plasminogen activators of type 1 (IPA-1) in patients with antiphospholipid syndrome (APS) and to reveal correlations between their content and clinical-laboratory characteristics of APS.
E V Ostryakova, T M Reshetnyak, R B Aisina, L I Mukhametova, D A Gulin, E N Alexandrova, N V Seredavkina, S D Varfolomeev, A V Chernyakov, Yu V Nikiforov, E L Nasonov   +10 more
doaj  

Thrombotic risk markers: tissue plasminogen activator-inhibitor complex/ tissue plasminogen activator inhibitor-1 (part 2)

Вестник анестезиологии и реаниматологии
The fibrinolysis system is one of the most important regulators of homeostasis and participates in maintaining stable blood flow. The key element of this system is the balance of plasminogen activators and inhibitors, which can be considered as markers ...
M. M. Tanashyan, E. V. Roitman, A. A. Raskurazhev, P. I. Kuznetsova, A. S. Mazur   +4 more
doaj   +1 more source

Micrometer‐scale tPA beads amplify plasmin generation for enhanced thrombolytic therapy

Bioengineering & Translational Medicine
Rapid restoration of blood flow is critical in treating acute ischemic stroke. Current thrombolytic therapies using tissue plasminogen activator (tPA) are limited by low recanalization rates and risks of off‐target bleeding.
Matthew J. Osmond, Fabrice Dabertrand, Nidia Quillinan, Enming J. Su, Daniel A. Lawrence, David W. M. Marr, Keith B. Neeves   +6 more
doaj   +1 more source

Functional Stability of Plasminogen Activator Inhibitor-1

The Scientific World Journal, 2014
Plasminogen activator inhibitor-1 (PAI-1) is the main inhibitor of plasminogen activators, such as tissue-type plasminogen activator (t-PA) and urokinase-type plasminogen activator (u-PA), and a major regulator of the fibrinolytic system.
Songul Yasar Yildiz, Pinar Kuru, Ebru Toksoy Oner, Mehmet Agirbasli   +3 more
doaj   +1 more source

Recombinant Plasminogen Activator of the Sandworm (Perinereis aibuhitensis) Expression in Escherichia coli

Bioengineering
As an essential thrombolytic agent, the tissue plasminogen activator receives increasing attention due to its longer half-life, lower immunogenicity, and easier administration, which are superior to other thrombolytic agents.
Tuo Song, Xiaozhen Diao, Jun Cheng, Yang Man, Boyu Chen, Haixing Zhang, Wenhui Wu   +6 more
doaj   +1 more source

Biochemical and structural analyses suggest that plasminogen activators coevolved with their cognate protein substrates and inhibitors. [PDF]

J Biol Chem, 2019
Jendroszek A, Madsen JB, Chana-Muñoz A, Dupont DM, Christensen A, Panitz F, Füchtbauer EM, Lovell SC, Jensen JK.   +8 more
europepmc   +1 more source