Results 71 to 80 of about 3,326,153 (390)
Plasminogen activation in the musculoskeletal acute phase response: Injury, repair, and disease
Research and Practice in Thrombosis and Haemostasis, 2020 The musculoskeletal system is critical for movement and the protection of organs. In addition to abrupt injuries, daily physical demands inflict minor injuries, necessitating a coordinated process of repair referred to as the acute‐phase response (APR ...
Breanne H.Y. Gibson +4 more
doaj +1 more source
European Journal of Biochemistry, 1983 Culture supernatants from monolayers of human peripheral monocytes strongly inhibited colorimetric assays of urokinase in which plasmin was measured by esterolysis.
J. Golder, R. Stephens
semanticscholar +1 more source
HGF modulates actin cytoskeleton remodeling and contraction in testicular myoid cells [PDF]
, 2015 The presence of the HGF/Met system in the testicular myoid cells was first discovered by our group. However, the physiological role of this pathway remains poorly understood. We previously reported that HGF increases uPA secretion and TGF-β activation in
Angela, Catizone +6 more
core +1 more source
Advanced Science, EarlyView.CCN1 modulates the tumor microenvironment in pancreatic cancer by promoting collagen‐dependent chemokine production, thereby facilitating immune evasion. Deletion of CCN1 not only suppresses tumor growth but also enhances immune cell infiltration and increases tumor sensitivity to both chemotherapy and immunotherapy.
Hongjie Fan +9 more
wiley +1 more source
Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines. [PDF]
, 2019 BACKGROUND:Astrocytes contribute to the crosstalk that generates chronic neuro-inflammation in neurological diseases; however, compared with microglia, astrocytes respond to a more limited continuum of innate immune system stimulants.
Azmoon, Pardis +8 more
core +1 more source
Analysis of the plasminogen activator activity of the human glomerulus [PDF]
, 1988 Analysis of the plasminogen activator activity of the human glomerulus. An assay was developed to measure plasminogen activator activity from isolated human glomeruli. Activator was extracted from individual glomeruli with 0.2 M phosphate-buffered saline,
Bang, Nils U. +2 more
core +1 more source
Advanced Science, EarlyView.Postoperative cardiac adhesions lead to numerous difficulties in reoperation procedures. Here, a thermo‐responsive in situ formed hydrogel is shown to can reliably cover the wounds after a convenient spraying or injection and significantly reduce adhesion formation in primary and recurrent cardiac injury adhesion models.
Kun Shi +11 more
wiley +1 more source
Needle detection and localisation for robot‐assisted subretinal injection using deep learning
CAAI Transactions on Intelligence Technology, EarlyView., 2023 Abstract Subretinal injection is a complicated task for retinal surgeons to operate manually. In this paper we demonstrate a robust framework for needle detection and localisation in robot‐assisted subretinal injection using microscope‐integrated Optical Coherence Tomography with deep learning.
Mingchuan Zhou +9 more
wiley +1 more source
Targeted Thrombolysis with Magnetic Nanotherapeutics: A Translational Assessment
PharmaceuticsPlasminogen activators, such as recombinant tissue-type plasminogen activators (rtPAs), while effective in treating thromboembolic diseases, often induce hemorrhagic complications due to non-specific enzyme activities in the systemic circulation.
Ming-Lu Lin +7 more
doaj +1 more source
Clinical significance of measuring plasminogen activator inhibitor-1 in sepsis
Journal of Intensive Care, 2017 Background Disseminated thrombotic process in the microcirculation is considered to be an important cause of multiple organ dysfunction in sepsis.
Toshiaki Iba, Jecko Thachil
doaj +1 more source