Results 81 to 90 of about 14,970 (304)
Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration
BMEMat, EarlyView.The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang +13 more
wiley +1 more source
The role of the fibrinolytic system in female reproductive disorders and depression
Thrombosis Update, 2020 Tissue plasminogen activator (tPA) and urinary plasminogen activator (uPA or urokinase) have important functions in the extracellular matrix. In the reproductive system, for example, tPA and uPA mediate tissue remodeling required for ovulation ...
Silvia Hoirisch-Clapauch +1 more
doaj +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Carotid free‐floating thrombus (CFFT) is a rare yet severe cause of the ischemic stroke. Early identification and appropriate management are crucial to prevent recurrent embolic events. A 76‐year‐old man experienced sudden left‐sided hemiparesis and dysarthria.
Hirofumi Matsubara +3 more
wiley +1 more source
Contribution of macrophages to plasmin activity in ewe bulk milk
Italian Journal of Animal Science, 2010 A total of 225 bulk sheep milk samples were collected throughout lactation to assess the contribution of macrophages to the regulation of the plasmin/plasminogen system. Samples were analyzed for composition, milk renneting parameters, and for activities
M. Albenzio +5 more
doaj +1 more source
Purification and characterization of native bovine milk plasminogen activators
, 1992 The breakdown of milk proteins by proteases affects the quality of dairy products. The proteolysis results in changes in bovine milk viscosity, solubility, cheesemaking characteristics, cheese ripening and age gelation of UHT milk.
Lu, Dongjin David
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The study of molecular markers for the progression of Barrett's Oesophagus to adenocarcinoma to identify markers that can be used as diagnostic tools. [PDF]
, 2002 Barrett's oesophagus is a complication of gastro-oesophageal reflux disease and is the single most important predisposing factor for the development of adenocarcinoma of the oesophagus.
Cadd, Verity Anne
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, 1989 peer reviewedThe coupled photometric assay for plasminogen activator reported by Coleman and Green (1981) Methods in Enzymology (Lorand, L., Ed.), Vol. 80, pp.
Leprince, Pierre +5 more
core +1 more source
The axonally secreted serine proteinase inhibitor, neuroserpin, inhibits plasminogen activators and plasmin but not thrombin. [PDF]
, 1998 Neuroserpin is an axonally secreted serine proteinase inhibitor that is expressed in neurons during embryogenesis and in the adult nervous system. To identify target proteinases, we used a eucaryotic expression system based on the mouse myeloma cell line
Osterwalder, T +7 more
core +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler +4 more
wiley +1 more source
Mutant and chimeric recombinant plasminogen activators
, 1987 Mutant urokinase-type plasminogen activator (u-PA) genes and hybrid genes between tissue-type plasminogen activator (t-PA) and u-Pa have been designed to direct the synthesis of new plasminogen ...
Bollen, A. +7 more
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