Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis [PDF]
, 2003 Pemphigus is an autoimmune blistering disease of the skin and mucous membranes. It is caused by autoantibodies directed against desmosomes, which are the principal adhesion structures between epidermal keratinocytes.
Besch, R. +9 more
core +1 more source
BMC Cancer, 2006 Background Upregulation of endogenous angiostatin levels may constitute a novel anti-angiogenic, and therefore anti-tumor therapy. In vitro, angiostatin generation is a two-step process, starting with the conversion of plasminogen to plasmin by ...
Maass Cathy N +5 more
doaj +1 more source
Immunocytochemical Phenotyping of Disseminated Tumor Cells in Bone Marrow by uPA Receptor and CK18: Investigation of Sensitivity and Specificity of an Immunogold/Alkaline Phosphatase Double Staining Protocol [PDF]
, 1997 Phenotyping of cytokeratin (CK) 18-positive cells in bone marrow is gaining increasing importance for future prognostic screening of carcinoma patients. Urokinase-type plasminogen activator receptor (uPA-R) is one example of a potential aggressive marker
Allgayer, Heike +5 more
core +1 more source
Reproductive Biology and Endocrinology, 2019 Background The fibrinolytic system and its inhibitors play a number of roles, apart from their function in blood haemostasis and thrombosis, namely in ovarian folliculogenesis and in ovulation.
Genia F. Burchall +5 more
doaj +1 more source
Enhanced Expression of Plasminogen Activators and Inhibitor in the Healing of Tympanic Membrane Perforation in Rats. [PDF]
J Assoc Res Otolaryngol, 2023 Makuszewska M +5 more
europepmc +1 more source
Fructose-1,6-bisphosphate aldolase of Neisseria meningitidis binds human plasminogen via its C-terminal lysine residue [PDF]
, 2016 Neisseria meningitidis is a leading cause of fatal sepsis and meningitis worldwide. As for commensal species of human neisseriae, N. meningitidis inhabits the human nasopharynx and asymptomatic colonization is ubiquitous.
Lai, Si Kei +5 more
core +1 more source
Journal of the Formosan Medical Association, 2014 Explaining the risks and benefits of recombinant tissue-plasminogen activator (rtPA) to eligible patients with acute ischemic stroke (AIS) within a few minutes is important but difficult.
Cheng-Yang Hsieh +6 more
doaj +1 more source
Plasminogen Activators in Neurovascular and Neurodegenerative Disorders. [PDF]
Int J Mol Sci, 2021 Yepes M, Woo Y, Martin-Jimenez C.
europepmc +1 more source
Impact of proteolytic enzymes in colorectal cancer development and progression. [PDF]
, 2014 Tumor invasion and metastasis is a highly complicated, multi-step phenomenon. In the complex event of tumor progression, tumor cells interact with basement membrane and extracellular matrix components.
Barabás, Lóránd +4 more
core +1 more source
Plasmin: indigenous milk proteinase
Mljekarstvo, 2002 The most important characteristic of plasmin, as significant indigenous milk proteinase, its concentration, concentration measuring procedure and activity of plasmin are described.
Samir Kalit +2 more
doaj