Results 101 to 110 of about 13,552 (164)

Plasminogen activator inhibitor-1 as an oncologic target: biology, therapeutic inhibitors, and clinical translation. [PDF]

Front Oncol
Al Shaer NSH, Tleyjeh A, Al-Attas MA, Alibrahim JH, Khan MI, Yaqinuddin A.   +5 more
europepmc   +1 more source

Double-edged sword: flavivirus NS1 enhances human plasmin-mediated fibrinolysis while being targeted for cleavage and inactivation. [PDF]

J Gen Virol
Mendes-Monteiro L, Carneiro PH, N Conde J, L Menezes J, Silva de Souza M, F de Carvalho P, D Hottz E, Harris E, Allonso D, Mohana-Borges R.   +9 more
europepmc   +1 more source

Plasmin-Plasminogen System and Milk Physicochemical Traits in Intensively Reared Chios and Frizarta Ewes: Effects of Lactation Stage, Age, and Somatic Cell Count. [PDF]

Animals (Basel)
Kalogianni AI, Dalaka E, Theodorou G, Politis I, Gelasakis AI.   +4 more
europepmc   +1 more source

Tissue Plasminogen Activator as an Approved Strategy for Ischemic Stroke: A Review of tPA's Structure, Mechanism of Action and the Novel Targeting Methods. [PDF]

J Mol Neurosci
Didehvar K, Haghshenas M, Yarmohammadi R, Hajikarimloo B, Ghafoury R.   +4 more
europepmc   +1 more source

M1 protein from group A <i>Streptococcus</i> affects fibrin clot formation, structure, and fibrinolytic potential. [PDF]

Blood Vessel Thromb Hemost
Cherrington S, Hardy LJ, Maqbool A, Philippou H, Thelwell C.   +4 more
europepmc   +1 more source

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Plasminogen activators and plasminogen activator inhibitors in endometriosis

Frontiers in Bioscience, 2005
Endometriosis is one of the most frequent benign gynecological diseases that affect women. Little is known about the pathogenesis and etiology of endometriosis, despite the numerous studies performed in this field. Although endometriosis is a benign disease, the endometrial tissue, after attachment to the peritoneum, has the ability to grow and invade ...
Juan, Gilabert-Estelles, Remedios, Castello, Juan, Gilabert, Luis Andres, Ramon, Francisco, Espana, Alberto, Romeu, Amparo, Estelles   +6 more
openaire   +4 more sources

Interaction of heparin with plasminogen activators and plasminogen: effects on the activation of plasminogen

Biochemistry, 1986
The amidolytic plasmin activity of a mixture of tissue plasminogen activator (tPA) and plasminogen is enhanced by heparin at therapeutic concentrations. Heparin also increases the activity in mixtures of urokinase-type plasminogen activator (uPA) and plasminogen but has no effect on streptokinase or plasmin. Direct analyses of plasminogen activation by
P, Andrade-Gordon, S, Strickland
openaire   +2 more sources

Mechanisms of Plasminogen Activation by Mammalian Plasminogen Activators

Enzyme, 2017
Plasminogen activators convert the proenzyme plasminogen to the active serine protease plasmin by hydrolysis of the Arg^560-Val^561 peptide bond. Physiological plasminogen activation is however regulated by several additional molecular interactions resulting in fibrin-specific clot lysis.
H R, Lijnen, D, Collen
openaire   +2 more sources

Plasminogen Activator and Plasminogen Activator Inhibitor Activities in a Reference Population

American Journal of Clinical Pathology, 1988
The influence of age, gender, and aspirin ingestion on plasma levels of tissue plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) activities was studied in a reference population of 35 men and 35 women between the ages of 20 and 65 years.
C, Krishnamurti, D B, Tang, C F, Barr, B M, Alving   +3 more
openaire   +2 more sources