Results 121 to 130 of about 91,776 (288)

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

Responsive Materials, EarlyView.
This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang, Xuan Hou, Haiping Zhao, Qi Kong, Xiayan Wang, Xiaokun Geng, Zaicheng Sun   +6 more
wiley   +1 more source

Immunological characterization of plasminogen activator activities in human tissues and body fluids

, 1981
Human plasminogen activators were compared immunologically in both a double-diffusion technique and quenching experiments on the fibrinolytic activities of the activators.
Rijken, D.C., Wijngaards, G., Welbergen, J.   +2 more
core  

Decreased Production of Tissue Plasminogen Activator in Endothelial Cells From Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Previous studies have demonstrated that chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by excessive fibrin deposition which is related to impaired production of tissue plasminogen activator(t‐PA) by epithelial cells.
Qian‐Qian Zhang, Chen Zhang, Jia‐Ni Chen, Fu‐Ying Cheng, Yi‐Zhang Wang, Shi‐Rui Xue, Huan Wang, De‐Hui Wang, Xi‐Cai Sun, Li Hu   +9 more
wiley   +1 more source

Studies on the fibrinolytic system in human plasma : Quantitative determination of plasminogen activators and proactivators

, 1979
Effects due to plasma plasminogen activators and proactivators are usually studied in assay systems where inhibitors influence the activity and where the degree of activation of proactivators is unknown.
Kluft, C.
core  

Current Advances of Treatments, Therapeutic Targets, Biomarkers, Novel Drugs, and Machine Learning for Hypopharyngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li, Rui Guan, Rui‐Jie Jiao, Zhi‐Jie Bi, Yang Fu, Yin Wang, Chen‐Yang Xu, Ye Qian, Ran Wei, Sheng‐Da Cao, Wen‐Ming Li, Dong‐Min Wei, Da‐Peng Lei   +12 more
wiley   +1 more source

Activators and inhibitors of the plasminogen system in Alzheimer's disease

, 2012
Accumulation and deposition of Aβ is one of the main neuropathological hallmarks of Alzheimer's disease (AD) and impaired Aβ degradation may be one mechanism of accumulation.
Barker, Rachel, Seth Love, Love, Seth, Patrick G. Kehoe, Rachel Barker, Kehoe, Patrick G   +5 more
core   +1 more source

Turbinoplasty Versus Medical Treatment for Allergic Rhinitis: A Systematic Review and Meta‐Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Allergic rhinitis is a common chronic condition affecting up to 30% of adults worldwide, with nasal obstruction being the most bothersome symptom. Inferior turbinate hypertrophy is a major contributor to nasal obstruction in allergic rhinitis, and surgical reduction techniques have been developed for cases refractory to medical ...
Noof Albannai, Hajar Alismail, Abdullah N. Aladwani, Abdur Rehman, Abdullah AlShuaib, Retaj Alawadhi, Jassim AlMusaileem, Meshal T. Alshammari, Omar Bader Alharbi, Bader A. Alasoosi, Sarah S. Alenezi, Abdullah M. Alharran, Ebraheem Albazee   +12 more
wiley   +1 more source

The Effects of Sodium Citrate and an Excess of Plasminogen on Fibrinolytic Agents

, 1960
Summary1. The presence of citrate in the normal fibrin enhanced the fibrinolytic activity of plasminogen activators, including trypsin. The effect of proteases (on normal or on heated fibrin, containing citrate) was not significantly influenced.2.
Tage Astrup, Ida Sterndorff
core   +1 more source

Changes of Microbial and Component Composition of Giraffe Milk During Mid‐ to Late Lactation

Zoo Biology, EarlyView.
Giraffe milk – graphical abstract text, Giraffe: late lactation milk, Involution at approximately 15 months of lactation, Content of saccharides and fat decrease, Protein content increases, Content of minerals increase, Microbiological quality high ABSTRACT The proximate, mineral and microbiological composition of milk from five giraffes from mid ...
G. Osthoff, C. J Hugo, S Van der Merwe, A Hugo, F Deacon   +4 more
wiley   +1 more source