Results 41 to 50 of about 648 (173)
Endocytosis of glycosylphosphatidylinositol-anchored proteins [PDF]
, 2009 Glycosylphosphatidylinositol-anchored proteins (GPI-APs) represent an interesting amalgamation of the three basic kinds of cellular macromolecules viz. proteins, carbohydrates and lipids.
De, Ananya +2 more
core +3 more sources
Peptide-mediated inactivation of recombinant and platelet plasminogen activator inhibitor-1 in vitro. [PDF]
Journal of Clinical Investigation, 1995 Plasminogen activator inhibitor-1 (PAI-1), the primary inhibitor of tissue-type plasminogen activator (t-PA) and urokinase plasminogen activator, is an important regulator of the blood fibrinolytic system. Elevated plasma levels of PAI-1 are associated with thrombosis, and high levels of PAI-1 within platelet-rich clots contribute to their resistance ...
D T, Eitzman +6 more
openaire +2 more sources
Biomolecular Corona of Gold Nanoparticles: The Urgent Need for Strong Roots to Grow Strong Branches
Small, Volume 20, Issue 15, April 11, 2024.This review presents a critical analysis of the current methodologies to decipher bio‐nano interactions by analyzing the biomolecular corona using gold nanoparticles as a case study. The study aims for a collective effort of the nano‐community through standardization of methodologies (for synthesis, characterization, and omics), data sharing, and ...
Luca Boselli +4 more
wiley +1 more source
Thrombolysis and interventional cardiology; experiences from the 80's [PDF]
, 1992 In October 1978 I assumed the position of cardiologist at the Catharina Hospital in Eindhoven at the time when the cardiothoracic surgery programm began in this hospital.
Bonnier, J.J.R.M. (Hans)
core
Effects of Brassicaceae Isothiocyanates on Prostate Cancer [PDF]
, 2016 Despite the major progress made in the field of cancer biology, cancer is still one of the leading causes of mortality, and prostate cancer (PCa) is one of the most encountered malignancies among men.
CARTEA, ELENA +4 more
core +2 more sources
Washington University Record, October 8, 1992 [PDF]
, 1992 https://digitalcommons.wustl.edu/record/1596/thumbnail ...
core +1 more source
International Journal of Molecular Medicine, 2010 Proteolysis in general and particularly the serine proteases are causally involved in many physiological processes and different diseases. Recently it was reported that plasminogen activator inhibitor type one (PAI-1) inactivation can alleviate the symptoms of Alzheimer's disease and reduce the body weight of obese individuals.
Ewa, Skrzypczak-Jankun, Jerzy, Jankun
openaire +3 more sources
Sepsis: From Bench to Bedside [PDF]
, 2008 Sepsis is a syndrome related to severe infections. It is defined as the systemic host response to microorganisms in previously sterile tissues and is characterized by end-organ dysfunction away from the primary site of infection. The normal host response
de Figueiredo, Luiz Francisco Poli +3 more
core +4 more sources
The urokinase-type plasminogen activator, its inhibitors and its receptor - the new prognostic factors in solid cancers [PDF]
, 1997 The urokinase-type plasminogen activator (uPA), its inhibitors (PAI-1 and PAI-2) and its receptor (uPAR) play nan important role in the degradation of the intercellular tissue, the process which affects the ability of cancer cells to invade to ...
Borštnar, Simona +2 more
core +1 more source
Chemistry & Biology, 2013 Plasminogen activator inhibitor-1 (PAI-1), a serpin, is the physiological inhibitor of tissue-type and urokinase-type plasminogen activators and thus also an inhibitor of fibrinolysis and tissue remodeling. It is a potential therapeutic target in many pathological conditions, including thrombosis and cancer.
Lin, Zhonghui +6 more
openaire +2 more sources