Dual mutation (MTHFR A1298C with PAI (4G) mutation) manifesting with bilateral lower limb gangrene in a neonate. [PDF]
BMJ Case Rep, 2021 Kumar A +3 more
europepmc +1 more source
Plasminogen activator inhibitor is significantly elevated in liver transplant recipients with decompensated NASH cirrhosis. [PDF]
BMJ Open Gastroenterol, 2021 Rivas G +4 more
europepmc +1 more source
Prion diseases: actual clinical and diagnostic aspects [PDF]
, 2018 Prion diseases constitute a very specific group of neurodegenerative disorders. Despite many years of studies, little avail was achieved in terms of effective treatment.
Akimova, P. O. +15 more
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Clinical Efficacy of Soluble Thrombomodulin, Tissue Plasminogen Activator Inhibitor complex, Thrombin-Antithrombin complex,α2-Plasmininhibitor-Plasmin complex in Pediatric Sepsis. [PDF]
Clin Appl Thromb Hemost, 2022 Li J +6 more
europepmc +1 more source
Computing Network of Diseases and Pharmacological Entities through the Integration of Distributed Literature Mining and Ontology Mapping [PDF]
, 2011 The proliferation of -omics (such as, Genomics, Proteomics) and -ology (such as, System Biology, Cell Biology, Pharmacology) have spawned new frontiers of research in drug discovery and personalized medicine.
Faisal, Fazle Elahi
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PREPARATION AND EVALUATION OF PEPTIDYL ACYLOXYMETHYL KETONES FOR CATHEPSIN B IMAGING [PDF]
, 2011 This thesis describes the initial steps towards the use of dipeptidyl acyloxymethyl ketones as a platform to develop molecular imaging (MI) probes for cancer.
Edem, Patricia
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The Multifaceted Role of Plasminogen in Cancer. [PDF]
Int J Mol Sci, 2021 Heissig B +4 more
europepmc +1 more source
Activation of Cyclic Phenol Phosphate Analogues as Potential Inhibitors of Autotaxin [PDF]
, 2017 Autotaxin (ATX) is a member of the nucleotide pyrophosphatase/phosphodiesterase family of ectoenzymes (NPP/ENPP). ATX is mostly present in blood, but it is also expressed at high levels in the brain, kidney, lymphoid organs, ovary, lung, and intestine ...
Algabbass, Kholud Ali
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Stroke as a Paraneoplastic Manifestation of Ovarian Cancer: A Case Report. [PDF]
Cureus, 2022 Tandi R +8 more
europepmc +1 more source
Structure-activity relationships of PAI-1 inhibitors [PDF]
, 2010 The inhibition of plasminogen activator inhibitor-1 (PAI-1) is anticipated to increase our understanding of various human ailments with which high levels of PAI-1 have been associated, including diabetes, stroke, and atherosclerosis.
Sanders, Karen
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