Results 11 to 20 of about 11,537,830 (293)
Platelet Function in Aging [PDF]
Frontiers in Cardiovascular Medicine, 2019 Aging is associated with an increased incidence of cardiovascular disease and thrombosis. Platelets play a major role in maintaining hemostasis and in thrombus formation, making them a key player in thrombotic disorders.
Jessica Le Blanc +3 more
doaj +5 more sources
Screening for platelet function disorders with Multiplate and platelet function analyzer
Platelets, 2019 Light transmission aggregation (LTA) is the gold standard for the diagnosis of platelet function disorders (PFDs), but it is time-consuming and limited to specialized laboratories.
Floor C. J. I. Moenen +10 more
doaj +2 more sources
Normal platelet function [PDF]
Cancer and Metastasis Reviews, 2017 Platelets play an important role in the vessel. Following their formation from megakaryocytes, platelets exist in circulation for 5-7 days and primarily function as regulators of hemostasis and thrombosis. Following vascular insult or injury, platelets become activated in the blood resulting in adhesion to the exposed extracellular matrix underlying ...
M. Holinstat
openaire +3 more sources
Seminars in Thrombosis and Hemostasis, 2016 Traditionally developed for diagnosis of bleeding disorders, platelet function assays have become increasingly used in basic research on platelet physiology, in phenotype-genotype associations in bleeding disorders, in drug development as surrogate endpoints of efficacy of new antiplatelet therapy, and to an extent, in the monitoring of antiplatelet ...
M. Lordkipanidzé
openaire +4 more sources
Corrigendum: The Effect of a Simulated Commercial Flight Environment With Hypoxia and Low Humidity on Clotting, Platelet, and Endothelial Function in Participants With Type 2 Diabetes – A Cross-Over Study [PDF]
Frontiers in Endocrinology, 2018 Aims: To determine if clotting, platelet, and endothelial function were affected by simulated short-haul commercial air flight conditions (SF) in participants with type 2 diabetes (T2DM) compared to controls. Methods: 10 participants with T2DM (7 females,
Judit Konya +9 more
doaj +6 more sources
Ontogeny of platelet function [PDF]
Blood Advances, 2019 AbstractAlthough the hemostatic potential of adult platelets has been investigated extensively, regulation of platelet function during fetal life is less clear. Recent studies have provided increasing evidence for a developmental control of platelet function during fetal ontogeny.
Andreas Margraf +2 more
openaire +3 more sources
Platelet function and ageing [PDF]
Mammalian Genome, 2016 There are clear age-related changes in platelet count and function, driven by changes in hematopoietic tissue, the composition of the blood and vascular health. Platelet count remains relatively stable during middle age (25-60 years old) but falls in older people. The effect of age on platelet function is slightly less clear.
Chris I. Jones
openaire +4 more sources
Pharmacological actions of nobiletin in the modulation of platelet function [PDF]
British Journal of Pharmacology, 2015 Background and Purpose The discovery that flavonoids are capable of inhibiting platelet function has led to their investigation as potential antithrombotic agents.
Ali, Marfoua +9 more
core +2 more sources
An Insight into Recent Advances on Platelet Function in Health and Disease
International Journal of Molecular Sciences, 2022 Platelets play a variety of roles in vascular biology and are best recognized as primary hemostasis and thrombosis mediators. Platelets have a large number of receptors and secretory molecules that are required for platelet functionality. Upon activation,
P. K. Chaudhary +2 more
semanticscholar +1 more source
Platelet Function in CKD: A Systematic Review and Meta-Analysis
Journal of the American Society of Nephrology, 2021 Visual Abstract Significance Statement Thrombotic and hemorrhagic complications frequently present in patients with CKD, and abnormalities in platelet function are central to thrombotic and hemorrhagic events. To clarify how CKD affects platelet function,
C. Baaten +5 more
semanticscholar +1 more source