Results 41 to 50 of about 1,059,321 (361)
Impact of platelet count on results obtained from multiple electrode platelet aggregometry (Multiplate™) [PDF]
Objectives Use of potent antiplatelet drugs requires evaluation of platelet function. While platelet function in elective cases is usually assessed in a central laboratory environment, there is also an urgent need for rapid perioperative point-of-care ...
Görlinger, K+6 more
core +3 more sources
Background and Purpose: Stent-assisted coiling (SAC) of intracranial aneurysms is usually treated with antiplatelet therapy to reduce the risk of postoperative ischemic events.
Yuanshu Li+6 more
doaj +1 more source
Identification of a functional genetic variant driving racially dimorphic platelet gene expression of the thrombin receptor regulator, PCTP. [PDF]
Platelet activation in response to stimulation of the Protease Activated Receptor 4 (PAR4) receptor differs by race. One factor that contributes to this difference is the expression level of Phosphatidylcholine Transfer Protein (PCTP), a regulator of ...
Bray, Paul F.+5 more
core +2 more sources
Extracellular vesicles (EV) act as a cellular communication tool by carrying lipids, proteins and micro RNA (miR) between cells, thereby playing a pivotal role in thromboembolic processes.
Paul M Haller+8 more
doaj +1 more source
Patients With Multiple Myeloma Have a Disbalanced Whole Blood Thrombin Generation Profile
BackgroundMultiple myeloma (MM) is associated with a high prevalence of bleeding and an increased risk of thrombo-embolism. MM patients have reduced platelet- and red blood cell (RBC) numbers in blood, which may indicate that the paradoxical hemostasis ...
Li Li+15 more
doaj +1 more source
Three-dimensional Multiscale Model of Deformable Platelets Adhesion to Vessel Wall in Blood Flow [PDF]
When a blood vessel ruptures or gets inflamed, the human body responds by rapidly forming a clot to restrict the loss of blood. Platelets aggregation at the injury site of the blood vessel occurring via platelet-platelet adhesion, tethering and rolling on the injured endothelium is a critical initial step in blood clot formation.
arxiv +1 more source
Design, Uncertainty Analysis and Measurement of a Silicon-based Platelet THz Corrugated Horn [PDF]
Platelets corrugated horn is a promising technology for their scalability to a large corrugated horn array. In this paper, we present the design, fabrication, measurement and uncertainty analysis of a wideband 170-320 GHz platelet corrugated horn that features with low sidelobe across the band (<-30 dB). We also propose an accurate and universal method
arxiv +1 more source
Platelet Function Monitoring in Patients With Coronary Artery Disease [PDF]
Studies focused on patient responsiveness to antiplatelet therapies, particularly aspirin and clopidogrel, have increased in recent years. However, the relations of in vivo platelet function and adverse clinical events to results of ex vivo platelet ...
Becker, Richard C.+4 more
core +1 more source
Thrombocytopenia is a common hematological abnormality in patients with cirrhotic hypersplenism. Splenectomy with paraesophagogastric devascularization (SPD) is a conventional surgical therapy which can reverse pancytopenia in these patients.
Hui Zhang+10 more
doaj +1 more source
PurposePrevious trials have demonstrated that ticagrelor was superior to clopidogrel in acute coronary syndrome (ACS) patients. However, several recent studies showed that ticagrelor was associated with a significantly higher risk of bleeding compared ...
Wenxing Peng+3 more
doaj +1 more source