Platelet function tests: a comparative review. [PDF]
Rita Paniccia,1,2 Raffaella Priora,1,2 Agatina Alessandrello Liotta,2 Rosanna Abbate1,2 1Department of Experimental and Clinical Medicine, Thrombosis Center, University of Florence, Florence, Italy; 2Department of Heart and Vessels, Azienda Ospedaliero ...
Paniccia R +3 more
europepmc +6 more sources
A Sticky Situation: Variable Agreement Between Platelet Function Tests Used to Assess Anti-platelet Therapy Response. [PDF]
BackgroundPlatelet function testing to monitor antiplatelet therapy is important for reducing thromboembolic complications, yet variability across testing methods remains challenging.
Nakahara H +8 more
europepmc +2 more sources
Clopidogrel versus ticagrelor in the treatment of Chinese patients undergoing percutaneous coronary intervention: effects on platelet function assessed by platelet function tests and mean platelet volume. [PDF]
Background Knowledge on the pharmacodynamic effects of antiplatelet drugs including clopidogrel and ticagrelor on Asian patients is scarce. We aim to evaluate the effects of the two drugs on platelet reactivity in the treatment of Chinese patients who ...
Zhang Y +8 more
europepmc +2 more sources
Utility of preoperative in vitro platelet function tests for predicting bleeding risk in patients undergoing functional endoscopic sinus surgery. [PDF]
A-Jin Lee, Sang-Gyung Kim Department of Laboratory Medicine, Catholic University of Daegu School of Medicine, Daegu, Republic of Korea Background: It is necessary to predict the bleeding risk in patients undergoing functional endoscopic sinus ...
Lee AJ, Kim SG.
europepmc +2 more sources
Early Platelet Dysfunction in Sepsis: An ICU Pilot Study [PDF]
Platelets are critical for hemostasis and play an active role in immune responses to infection. While thrombocytopenia in sepsis is associated with poor outcomes, platelet dysfunction remains less explored.
Bocci M +15 more
europepmc +2 more sources
Platelet function tests: why they fail to guide personalized antithrombotic medication. [PDF]
Gorog DA, Jeong YH.
europepmc +2 more sources
Platelet function in overt hypothyroidism
BACKGROUND: Hypothyroidism is associated with a shift of the hemostatic system to a hypocoagulable state and inhibited platelet function. However, previous studies did not consider the different degrees of response to thyroxine treatment and its effect ...
Abeer Khalid Al-Ghumlas +2 more
doaj +1 more source
Platelet function tests are essential to profile platelet dysfunction and dysregulation in hemostasis and thrombosis. Clinically they provide critical guidance to the patient management and therapeutic evaluation.
Yingqi Zhang +8 more
doaj +1 more source
Optimized tool for evaluation of platelet function measured by impedance aggregometry
Platelet aggregation measured by impedance aggregometry is highly dependent on platelet count. We previously developed a tool to interpret impedance aggregometry based on the strong linear correlation between platelet counts and platelet aggregation at ...
Anna Schultz-Lebahn +3 more
doaj +1 more source
Traditionally developed for diagnosis of bleeding disorders, platelet function assays have become increasingly used in basic research on platelet physiology, in phenotype-genotype associations in bleeding disorders, in drug development as surrogate endpoints of efficacy of new antiplatelet therapy, and to an extent, in the monitoring of antiplatelet ...
openaire +3 more sources

