Results 1 to 10 of about 160,648 (299)

Platelet function tests, independent of platelet count, are associated with bleeding severity in ITP. [PDF]

Blood, 2015
Frelinger AL, Grace RF, Grace RF, Gerrits AJ, Berny-Lang MA, Brown T, Carmichael SL, Neufeld EJ, Michelson AD.   +8 more
europepmc   +2 more sources

Haemostasis alterations in immune thrombocytopenia and their clinical significance [PDF]

Research and Practice in Thrombosis and Haemostasis
Immune thrombocytopenia (ITP) is highly heterogeneous, and only a subset of patients with severe thrombocytopenia develops significant bleeding. ITP is also associated with a paradoxical increased risk of thrombosis.
Thomas Pincez, Natalie Mathews, Arnaud Bonnefoy   +2 more
doaj   +2 more sources

Platelet Function Tests: Why They Fail to Guide Personalized Antithrombotic Medication [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Diana A. Gorog, Young‐Hoon Jeong
doaj   +2 more sources

Anti-platelet Therapy Resistance - Concept, Mechanisms and Platelet Function Tests in Intensive Care Facilities. [PDF]

J Crit Care Med (Targu Mures), 2016
Mărginean A, Bănescu C, Scridon A, Dobreanu M.   +3 more
europepmc   +3 more sources

Platelet function in overt hypothyroidism

Journal of Applied Hematology, 2021
BACKGROUND: Hypothyroidism is associated with a shift of the hemostatic system to a hypocoagulable state and inhibited platelet function. However, previous studies did not consider the different degrees of response to thyroxine treatment and its effect ...
Abeer Khalid Al-Ghumlas, Aishah Ali Ekhzaimy, Abdel Galil Mohammad Abdel Gader   +2 more
doaj   +1 more source

Optimized tool for evaluation of platelet function measured by impedance aggregometry

Platelets, 2021
Platelet aggregation measured by impedance aggregometry is highly dependent on platelet count. We previously developed a tool to interpret impedance aggregometry based on the strong linear correlation between platelet counts and platelet aggregation at ...
Anna Schultz-Lebahn, Mette Tiedemann Skipper, Anne-Mette Hvas, Ole Halfdan Larsen   +3 more
doaj   +1 more source

Platelet Function Tests [PDF]

Seminars in Thrombosis and Hemostasis, 2016
Traditionally developed for diagnosis of bleeding disorders, platelet function assays have become increasingly used in basic research on platelet physiology, in phenotype-genotype associations in bleeding disorders, in drug development as surrogate endpoints of efficacy of new antiplatelet therapy, and to an extent, in the monitoring of antiplatelet ...
openaire   +3 more sources

Perioperative management and monitoring of antiplatelet agents: a focused review on aspirin and P2Y inhibitors [PDF]

Korean Journal of Anesthesiology, 2017
Platelets play pivotal roles in hemostasis as well as pathological arterial thrombosis. The combination of aspirin and a P2Y12 inhibitor has become the mainstay therapy in the ageing population with cardiovascular conditions, particularly during and ...
Michael A. Mazzeffi, Khang Lee, Bradley Taylor, Kenichi A. Tanaka   +3 more
doaj   +1 more source

Antiplatelet therapy – platelet function test for platelet response assessment [PDF]

Българска кардиология
Dual antiplatelet therapy is the main pharmacological mechanism used to suppress platelet function in order to prevent thrombotic complications following percutaneous coronary angioplasty.
D. Dineva, Е. Doncheva, I. Paskaleva
doaj   +3 more sources

Stability and utility of flow cytometric platelet activation tests: A modality to bridge the gap between diagnostic demand and supply

Platelets, 2022
Light transmission aggregometry (LTA) is the gold standard for the diagnosis of platelet function disorders (PFDs). The requirement of customized aggregometer, large blood volume, normal platelet count and processing within 4 hours of venipuncture for ...
Rutvi Gautam Dave, Tulasi Geevar, Gayathiri Kaduvetti Chellaiya, Joy John Mammen, Ramya Vijayan, Ashok Samuel, Mahasampath Gowri, Sukesh Chandran Nair   +7 more
doaj   +1 more source