Results 11 to 20 of about 764,489 (264)

Platelet dysfunction and inhibition of multiple electrode platelet aggregometry caused by penicillin [PDF]

, 2010
Beta-lactam antibiotics, e.g. penicillin, may inhibit platelet function and lead to reduced response in light transmission aggregometry and adhesion. However, influence on platelet function tests more commonly used in clinical practice, such as multiple ...
Massberg, Steffen, Okrojek, Rainer, Schulz, Christian, von Beckerath, Nicolas, von Beckerath, Olga   +4 more
core   +3 more sources

Rupture Forces among Human Blood Platelets at different Degrees of Activation [PDF]

, 2020
Little is known about mechanics underlying the interaction among platelets during activation and aggregation. Although the strength of a blood thrombus has likely major biological importance, no previous study has measured directly the adhesion forces of single platelet-platelet interaction at different activation states.
arxiv   +1 more source

Platelet Function and Genetic Testing

Journal of the American College of Cardiology, 2013
#### Perspective: Platelet and Genetic Testing for Clopidogrel Hyporesponsiveness Use as a Research Tool Dr. Angiolillo has received payment as an individual for consulting fee or honorarium from Bristol-Myers Squibb, Sanofi-Aventis, Eli Lilly, Daiichi Sankyo, The Medicines Company, AstraZeneca,
José Luis Ferreiro, Dominick J. Angiolillo, Gregg W. Stone, Ajay J. Kirtane, Matthew J. Price   +4 more
openaire   +3 more sources

Platelet Function Monitoring in Patients With Coronary Artery Disease [PDF]

, 2007
Studies focused on patient responsiveness to antiplatelet therapies, particularly aspirin and clopidogrel, have increased in recent years. However, the relations of in vivo platelet function and adverse clinical events to results of ex vivo platelet ...
Becker, Richard C., Gurbel, Paul A., Mann, Kenneth G., Michelson, Alan D., Steinhubl, Steven R.   +4 more
core   +1 more source

DNA-based Diagnosis of Uncharacterized Inherited Macrothrombocytopenias Using Next-generation Sequencing Technology with a Candidate Gene Array [PDF]

, 2016
Inherited macrothrombocytopenias comprise a heterogeneous group of inherited platelet disorders that are characterized by large platelets, thrombocytopenia and bleeding tendencies in affected individuals.
Chen, Qiang, Gabrielli, Sara, Morel Kopp, Marie-Christine, Rabbolini, David J., Stevenson, William S., Ward, Christopher M.   +5 more
core   +1 more source

Assessing the Current Role of Platelet Function Testing [PDF]

, 2008
In vitro platelet function tests are commonly applied in research and offer justification for using antiplatelet therapy. However, studies assessing the ability of standardized platelet function tests to predict patients' clinical response to aspirin or ...
Ajzenberg, American College of Cardiology/American Heart Association Task Force on Practice Guidelines, Barragan, Chen, Eikelboom, Gum, Gum, Gurbel, Gurbel, Gurbel, Gurbel, Harrison, Iakovou, Joner, Matetzky, McFadden, Michelson, Michelson, Michelson, Michelson, Michelson, Michelson, Ohmori, Task Force on the Use of Antiplatelet Agents in Patients with Atherosclerotic Cardiovascular Disease of the European Society of Cardiology, Wenaweser   +24 more
core   +1 more source

Clinical practice: The bleeding child. Part I: primary hemostatic disorders [PDF]

, 2012
Mucocutaneous bleeding is common in childhood and may be the result of primary hemostatic disorders such as vascular abnormalities, von Willebrand disease, thrombocytopenia, and platelet dysfunction.
Peters, Marjolein, van Ommen, C. Heleen
core   +3 more sources

Platelet function testing: dead or alive [PDF]

Journal of Thrombosis and Haemostasis, 2018
Essentials Pharmacodynamic response to antiplatelet medication is heterogeneous. Platelet reactivity to dual antiplatelet therapy was analyzed by three platelet function assays. The prevalence of high and low platelet reactivity differed significantly between assays.
Helten, C., Naguib, D., Dannenberg, L., Pöhl, M., Ayhan, A., Hohlfeld, T., Levkau, Bodo, Kelm, M., Zeus, T., Polzin, A.   +9 more
openaire   +4 more sources

Clinical utility of remote platelet function measurement using P-selectin: assessment of aspirin, clopidogrel, and prasugrel and bleeding disorders [PDF]

, 2018
Vascular diseases such as myocardial infarction and ischemic stroke are associated with increased platelet function whilst the risk of recurrence is reduced by antiplatelet agents such as aspirin, clopidogrel, and prasugrel.
Adamany J, Bath PM, May J, Flaherty K, Woodhouse LJ, Dovlatova N, Fox SC, England TJ, Krishnan K, Robinson TG, Sprigg N, et al., Bath PM, Woodhouse LJ, Appleton JP, Beridze M, Christensen H, Dineen RA, Duley L, England TJ, Flaherty K, Havard D, et al., Cardoso RN, Benjo AM, DiNicolantonio JJ, Garcia DC, Macedo FY, El-Hayek G, Nadkarni GN, Gili S, Iannaccone M, Konstantinidis I, et al., Dovlatova N, Fox SC, May JA, Dovlatova N, Glenn JR, Johnson A, White AE, Radhakrishnan A, Heptinstall S., Heptinstall S, Heptinstall S, Heptinstall S, Jane May, Laohathai P, Joshi R, Radhakrishnan A, May J, Dovlatova N, Heptinstall S, Fox S., May J, Philip M Bath, Stan Heptinstall, TARDIS Trial Investigators, Krishnan K, Beridze M, Christensen H, Dineen R, Duley L, Heptinstall S, James M, Markus H, Pocock S, et al., Vlachojannis G   +15 more
core   +2 more sources

Presence of factors that activate platelet aggregation in mitral stenotic patients' plasma [PDF]

, 2005
BACKGROUND: Although the association between mitral stenosis (MS) and increased coagulation activity is well recognized, it is unclear whether enhanced coagulation remains localized in the left atrium or whether this represents a systemic problem.
Can Duman, CW Chiang, D Tschoepe, DJ Sahn, Emin Alioglu, Ertugrul Ercan, Fahri Sahin, Filiz Buyukkececi, FL Li-Saw-Hee, G Pongratz, Guray Saydam, HA Fleming, I Hayashi, Istemihan Tengiz, J Bonnar, J Maly, JJ Hwang, K Yamamoto, KA Bauer, L Hatle, M Ileri, M Yasaka, MD Boisclair, R Atak, RE Peverill, S Kamath, S Rohmann   +26 more
core   +3 more sources