Results 11 to 20 of about 162,912 (259)
Perioperative management and monitoring of antiplatelet agents: a focused review on aspirin and P2Y inhibitors [PDF]
Korean Journal of Anesthesiology, 2017 Platelets play pivotal roles in hemostasis as well as pathological arterial thrombosis. The combination of aspirin and a P2Y12 inhibitor has become the mainstay therapy in the ageing population with cardiovascular conditions, particularly during and ...
Michael A. Mazzeffi +3 more
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Antiplatelet therapy – platelet function test for platelet response assessment [PDF]
Българска кардиологияDual antiplatelet therapy is the main pharmacological mechanism used to suppress platelet function in order to prevent thrombotic complications following percutaneous coronary angioplasty.
D. Dineva, Е. Doncheva, I. Paskaleva
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Platelets, 2022 Light transmission aggregometry (LTA) is the gold standard for the diagnosis of platelet function disorders (PFDs). The requirement of customized aggregometer, large blood volume, normal platelet count and processing within 4 hours of venipuncture for ...
Rutvi Gautam Dave +7 more
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The application value of determination of hemostasis and thrombosis in tumor patients [PDF]
Zhenduanxue lilun yu shijian, 2023 Abnormal coagulation function is an important feature of the occurrence and development of malignant tumors. Tumor cells release pro-angiogenic factors that cause vascular endothelial damage and induce platelet activation and proliferation, all of which ...
WANG Yanchun, LU Renquan
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Long-term treated HIV infection is associated with platelet mitochondrial dysfunction
Scientific Reports, 2021 HIV infection and antiretroviral therapy have been linked to mitochondrial dysfunction. The role of platelet mitochondrial dysfunction in thrombosis, immunoregulation and age-related diseases is increasingly appreciated.
Wouter A. van der Heijden +12 more
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Indian Journal of Pathology and Microbiology, 2018 Introduction: The platelet function disorders remain largely undiagnosed or incompletely diagnosed in developing nations due to lack of availability of tests like lumiaggregometry, granule release assay or molecular testing.
Sabina Langer +3 more
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Reduced platelet function in preterm neonates compared with term neonates
Research and Practice in Thrombosis and Haemostasis, 2022 Background A reduced platelet function might contribute to the longer bleeding time seen in preterm neonates. However, the previously used platelet function testing in neonates is limited due to methodological limitations, mainly caused by difficulties ...
Nadia Thrane Hovgesen +4 more
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Sticky Platelet Syndrome in Patients with Uninduced Venous Thrombosis
Turkish Journal of Hematology, 2013 OBJECTIVE: Sticky platelet syndrome (SPS) is a common autosomal dominant inherited platelet disorder. SPS is characterized by platelet hyperreactivity and is associated with arterial and venous thrombosis.
Emre Tekgündüz +5 more
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Platelet Contribution to Clot Strength in Thromboelastometry: Count, Function, or Both?
Platelets, 2020 In thromboelastometry (ROTEMTM) the difference in amplitude between the EXTEM and the FIBTEM is considered an index of platelet contribution to clot strength (PCSamp). The difference in elasticity (PCSel) is rarely used.
Marco Ranucci +2 more
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Research and Practice in Thrombosis and Haemostasis, 2019 Laboratory tests of platelet function are instrumental in studying platelet physiology and inherited or acquired platelet abnormalities. Light transmission aggregometry, developed in the early 1960s, is still considered the gold standard for the ...
Béatrice Hechler +3 more
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