Results 21 to 30 of about 162,912 (259)

Platelet Function Assays for the Diagnosis of Aspirin Resistance

Platelets, 2022
Aspirin, an antiplatelet drug, is commonly used at low doses for numerous indications, including prophylaxis of cardiovascular, neurovascular, and venous thromboembolic events.
Nameer Van Oosterom, Michael Barras, Neil Cottrell, Robert Bird   +3 more
doaj   +1 more source

Antiplatelet Therapy and Platelet Function Testing [PDF]

Clinical Cardiology, 2008
Eugene Braunwald,∗ Dominick Angiolillo,† Eric Bates,‡ Peter B. Berger,§ Deepak Bhatt,|| Christopher P. Cannon,∗ Mark I. Furman,¶ Paul Gurbel,∗∗ Alan D. Michelson,†† Eric Peterson,‡‡ Stephen Wiviott∗ ∗TIMI Study Group, Cardiovascular Division, Brigham and Women’s Hospital, Department of Medicine, Harvard Medical School, Boston, Massachusetts ...
Braunwald, Eugene, Angiolillo, Dominick, Bates, Eric R., Berger, Peter B., Bhatt, Deepak, Cannon, Christopher P., Furman, Mark I., Gurba, Paul E., Michelson, Alan D., Peterson, Eric, Wiviott, Stephen   +10 more
openaire   +5 more sources

Evaluation of an automated light transmission aggregometry

Platelets, 2017
Light transmission aggregometry (LTA) is the “gold standard” for platelet function assessment, but it is time-consuming and labor intensive. Recently, an automated platelet aggregation method has been developed on a routine coagulation analyzer (Sysmex ...
Li-qin Ling, Juan Liao, Qian Niu, Xia Wang, Jin Jia, Cheng-hua Zuo, Hong Jiang, Jing Zhou   +7 more
doaj   +1 more source

Platelet Function and Genetic Testing

Journal of the American College of Cardiology, 2013
#### Perspective: Platelet and Genetic Testing for Clopidogrel Hyporesponsiveness Use as a Research Tool Dr. Angiolillo has received payment as an individual for consulting fee or honorarium from Bristol-Myers Squibb, Sanofi-Aventis, Eli Lilly, Daiichi Sankyo, The Medicines Company, AstraZeneca,
Angiolillo, Dominick J., Ferreiro, José Luis, Price, Matthew J., Kirtane, Ajay J., Stone, Gregg W.   +4 more
openaire   +2 more sources

Impaired platelet function in Hermansky-Pudlak syndrome associated with novel mutations in HPS3, HPS6 and HPS8 genes

Bleeding, Thrombosis and Vascular Biology
We report three unrelated cases of Hermansky-Pudlak (HP) characterized by novel mutations in HPS3 (compound heterozygosity for c.1457G>A and c.1813G>T), HPS6 (homozygous c.210_211insGGGCC), and HPS8 (homozygous c.299dupC in BLOC1S3) genes.
Lisa Pieri, Silvia Linari, Francesca Salvianti, Monica Attanasio, Giancarlo Castaman   +4 more
doaj   +1 more source

Novel SLFN14 mutation associated with macrothrombocytopenia in a patient with severe haemorrhagic syndrome

Orphanet Journal of Rare Diseases, 2023
Background Platelet-type bleeding disorder 20 (BDPLT20), as known as SLFN14-related thrombocytopenia, is a rare inherited thrombocytopenia (IT). Previously, only 5 heterozygous missense mutations in the SLFN14 gene have been reported.
Dmitrii Polokhov, Daria Fedorova, Anastasiya Ignatova, Evgeniya Ponomarenko, Elena Rashevskaya, Alexey Martyanov, Nadezhda Podoplelova, Maxim Aleksenko, Irina Mersiyanova, Elena Seregina, Aleksandr Poletaev, Ekaterina Truchina, Elena Raykina, Svetlana Plyasunova, Galina Novichkova, Pavel Zharkov, Mikhail Panteleev   +16 more
doaj   +1 more source

Functional characterization of a nanobody-based glycoprotein VI-specific platelet agonist

Research and Practice in Thrombosis and Haemostasis
Background: Glycoprotein (GP)VI is a platelet-specific collagen receptor required for platelet activation during hemostasis. Platelet reactivity toward collagen is routinely assessed during diagnostic workup of platelet disorders.
Minka Zivkovic, Elisabeth Pols - van Veen, Vossa van der Vegte, Silvie A.E. Sebastian, Annick S. de Moor, Suzanne J.A. Korporaal, Roger E.G. Schutgens, Rolf T. Urbanus, Erik Beckers, Michiel Coppens, Jeroen Eikenboom, Louise Hooimeijer, Gerard Jansen, Roger Schutgens, Rolf Urbanus, Minka Zivkovic, Emile van den Akker, Wala Al Arashi, Ryanne Arisz, Lieke Baas, Ruben Bierings, Maartje van den Biggelaar, Johan Boender, Anske van der Bom, Mettine Bos, Martijn Brands, Annelien Bredenoord, Laura Bukkems, Lex Burdorf, Jessica Del Castillo Alferez, Michael Cloesmeijer, Marjon Cnossen, Mariëtte Driessens, Jeroen Eikenboom, Karin Fijnvandraat, Kathelijn Fischer, Geertje Goedhart, Tine Goedhart, Samantha Gouw, Rieke van der Graaf, Masja de Haas, Lotte Haverman, Jan Hazelzet, Shannon van Hoorn, Elise Huisman, Nathalie Jansen, Alexander Janssen, Sean de Jong, Sjoerd Koopman, Marieke Kruip, Sebastiaan Laan, Frank Leebeek, Nikki van Leeuwen, Hester Lingsma, Moniek de Maat, Ron Mathôt, Felix van der Meer, Karina Meijer, Sander Meijer, Stephan Meijer, Iris van Moort, Caroline Mussert, Hans Kristian Ploos van Amstel, Suzanne Polinder, Diaz Prameyllawati, Simone Reitsma, Eliza Roest, Lorenzo Romano, Saskia Schols, Roger Schutgens, Rolf Urbanus, Carin Uyl, Jan Voorberg, Huan Zhang, Minka Zivkovic   +74 more
doaj   +1 more source

Platelet phenotypes and practical aspects of platelet function testing in cardiology

Рациональная фармакотерапия в кардиологии, 2023
The assessment of platelet dysfunction is usually used by hematologists to diagnose inherited (such as Bernard-Soulier syndrome, platelet-type-von Willebrand disease, Glanzmann thrombasthenia, etc.), and acquired (symptomatic) platelet disorders (in ...
Zh. D. Kobalava, A. S. Pisaryuk, A. A. Filkova, E. S. Tukhsanboev, A. A. Boldyreva, D. P. Lazutova, I. A. Meray, M. A. Panteleev   +7 more
doaj   +1 more source

Aggregometry in the settings of thrombocytopenia, thrombocytosis and antiplatelet therapy

Platelets, 2018
A variety of laboratory tests have been developed, which can diagnose a number of both congenital and acquired disorders of platelet function. Many tests of platelet function measure the ability of platelets to adhere to each other, forming platelet ...
GianMarco Podda, Mariangela Scavone, Eti Alessandra Femia, Marco Cattaneo   +3 more
doaj   +1 more source

Platelet function in the postprandial period

Thrombosis Journal, 2012
Background Postprandial hyperlipidemia and hyperglycemia have been related to cardiovascular events. Among different underlying mechanisms platelet activation seems to be responsible too.
Sinzinger Helmut, Berent Robert
doaj   +1 more source