Impact of a high-fat meal on assessment of clopidogrel-induced platelet inhibition in healthy subjects. [PDF]
BACKGROUND: Ideal conditions for platelet reactivity testing are critical for optimal selection of a P2Y12 inhibitor. Data are inconsistent regarding the impact of high-fat meals on test assessment.
Dobesh, Paul P.+3 more
core +2 more sources
Probing a non-biaxial behavior of infinitely thin hard platelets [PDF]
We give a criterion to test a non-biaxial behavior of infinitely thin hard platelets of $D_{2h}$ symmetry based upon the components of three order parameter tensors. We investigated the nematic behavior of monodisperse infinitely thin rectangular hard platelet systems by using the criterion.
arxiv +1 more source
A Wigner-Seitz model of charged lamellar colloidal dispersions [PDF]
A concentrated suspension of lamellar colloidal particles (e. g. clay) is modelled by considering a single, uniformly charged, finite platelet confined with co- and counterions to a Wigner-Seitz (WS) cell. The system is treated within Poisson-Boltzmann theory, with appropriate boundary conditions on the surface of the WS cell, supposed to account for ...
arxiv +1 more source
Shape, connectedness percolation and electrical conductivity of clusters in suspensions of hard platelets [PDF]
Using Monte Carlo simulations, we investigate how geometric percolation and electrical conductivity in suspensions of hard conducting platelets are affected by the addition of platelets and their degree of spontaneous alignment. For aspect ratios $10, 25$ and $50$, we consistently observe a monotonically decreasing percolation threshold as a function ...
arxiv +1 more source
The importance of tests applied to evaluate the effectiveness of antiplatelet therapy in patients with recurrent coronary stent thrombosis [PDF]
Background. Stent thrombosis is potentially lethal complication with huge economic burden. The role of insufficient response to antiplatelet therapy is still unclear reason for its occurrence. Case report.
Cikota Bojana+10 more
core +1 more source
Platelet Inventory Management with Approximate Dynamic Programming [PDF]
We study a stochastic perishable inventory control problem with endogenous (decision-dependent) uncertainty in shelf-life of units. Our primary motivation is determining ordering policies for blood platelets. Determining optimal ordering quantities is a challenging task due to the short maximum shelf-life of platelets (3-5 days after testing) and high ...
arxiv
Density functional theory for colloidal mixtures of hard platelets, rods, and spheres [PDF]
A geometry-based density functional theory is presented for mixtures of hard spheres, hard needles and hard platelets; both the needles and the platelets are taken to be of vanishing thickness. Geometrical weight functions that are characteristic for each species are given and it is shown how convolutions of pairs of weight functions recover each Mayer
arxiv +1 more source
Three-dimensional Multiscale Model of Deformable Platelets Adhesion to Vessel Wall in Blood Flow [PDF]
When a blood vessel ruptures or gets inflamed, the human body responds by rapidly forming a clot to restrict the loss of blood. Platelets aggregation at the injury site of the blood vessel occurring via platelet-platelet adhesion, tethering and rolling on the injured endothelium is a critical initial step in blood clot formation.
arxiv +1 more source
Bulk and interfacial properties of binary hard-platelet fluids [PDF]
Interfaces between demixed fluid phases of binary mixtures of hard platelets are investigated using density-functional theory. The corresponding excess free energy functional is calculated within a fundamental measure theory adapted to the Zwanzig model, in which the orientations of the particles of rectangular shape are restricted to three orthogonal ...
arxiv +1 more source
Platelet Function Testing in Cardiovascular Diseases [PDF]
Case presentation 1: Mr F. is a 60-year-old man with unstable angina who takes aspirin, 81 mg/day. A platelet function test demonstrates that his platelets are “resistant” to aspirin. Should his treatment be changed? Case presentation 2: Mr K. is a 60-year-old man with unstable angina who takes aspirin, 81 mg/day, and clopidogrel, 75 mg/day.
openaire +6 more sources