Results 201 to 210 of about 40,413 (292)

Growth Differentiation Factor‐15 Could Predict Decreased Hemoglobin in Tuberculosis Treated With Linezolid‐Containing Regimen

The Clinical Respiratory Journal, Volume 20, Issue 5, May 2026.
Baseline GDF‐15 predicts linezolid‐induced myelosuppression in rifampicin‐resistant tuberculosis. Patients with higher pretreatment GDF‐15 (> 950 pg/mL) were more likely to develop significant hemoglobin decline during therapy. Measuring GDF‐15 before treatment may help identify high‐risk patients and guide safer, personalized linezolid use.
Amaylia Oehadian, Prayudi Santoso, Delita Prihatni, Andini Kartikasari, Ida Parwati, Diah Handayani, Thomas Handoyo, Noorwati Sutandiyo, Bachti Alisjahbana, Dick Menzies, Rovina Ruslami   +10 more
wiley   +1 more source

Acquired platelet disorders. [PDF]

Front Med (Lausanne)
Altahan RM.
europepmc   +1 more source

Beyond the chaos: How architecture structures tumour biology

The FEBS Journal, Volume 293, Issue 9, Page 2519-2540, May 2026.
Tissue architecture shapes tumour initiation and progression through multiple interconnected layers continuously remodelled over time. This review outlines how physical forces, biochemical cues, cellular niches and systemic influences contribute to tumour evolution.
Lea Dörner, Catrin Lutz, Stefan Prekovic, Hendrik A. Messal   +3 more
wiley   +1 more source

Molecular mechanism for platelet hyperreactivity in diabetes mellitus. [PDF]

J Diabetes Investig
Kaneto H.
europepmc   +1 more source

From Adipose Tissue to Cardiac Repair: Extracellular Vesicles in Cardiovascular Regeneration

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Adipose‐derived extracellular vesicles (ADEVs) secreted by adipose tissue have gained increasing attention due to their regenerative and immunomodulatory properties in cardiovascular diseases. They carry proteins, lipids, and nucleic acids that mediate intercellular communication and influence cardiac pathophysiology. In atherosclerosis, ADEVs
Karolina Ignaczak, Pola Ochocka, Karol Sadowski, Weronika Ploch, Dominika Tomkiel, Mariusz Tomaniak, Wioletta Olejarz   +6 more
wiley   +1 more source

Platelets from early-stage Alzheimer patients show enhanced amyloid binding, an elevated open canalicular system and sex-specific differences in their activation profile. [PDF]

Front Neurol
Donner L, Christl J, Kujovic M, Supprian T, Elvers M.   +4 more
europepmc   +1 more source

Sialidase Neu3 Induced Sialic Acid Disorder and Promoted Vascular Endothelial Injury Through Transcription Factor SP3

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Atherosclerotic cardiovascular disease is still a major cause for the increasing mortality worldwide. The elevated metabolite N‐acetylneuraminic acid (Neu5Ac) was considered one of the important risk factors responsible for the initiation of endothelial impairment, then participated in atherosclerosis progression.
Yining Lu, Peng Xiang, Qingqiu Chen, Xianmin Wang, Le Chen, Tongchuan Wang, Rong Hu, Limei Ma, Chao Yu   +8 more
wiley   +1 more source

Alzheimer's Disease-Associated Molecular Abnormalities in White Matter Glia and Related Pathologies Detected in Unfractionated and O4-Selected Serum Exosomes Using a Liquid Biopsy Approach. [PDF]

Biomedicines
de la Monte SM, Tong M.
europepmc   +1 more source

Chromaffin Versus Platelet Granules: What We Have Learned From Chromaffin Cells for Human Studies

Journal of Neurochemistry, Volume 170, Issue 5, May 2026.
Chromaffin cells and platelets both utilize exocytosis to release biogenic amines stored within large dense‐core vesicles—specifically chromaffin granules (epinephrine) and δ‐granules (serotonin). While the chromaffin cell is the foundational model for studying the secretory pathway, platelets offer a highly accessible human cell source for clinical ...
Ricardo Borges
wiley   +1 more source

The role of protease-activated receptors (PARs) in the functioning of platelets and platelet-derived microparticles (PMPs). [PDF]

Front Mol Biosci
Jakobsche-Policht U, Bronowicka-Szydełko A, Adamiec R, Bednarska-Chabowska D, Mierzchała-Pasierb M, Lewandowski Ł, Gostomska-Pampuch K, Adamiec-Mroczek J, Rabczyński M, Kuźnik E, Lubieniecki P, Dróżdż O, Martynowicz H, Kwiecień A, Strzelecka M, Rudkiewicz D, Piersiak M, Ziomek M, Kondracki M, Galińska Z, Madziarska K.   +20 more
europepmc   +1 more source