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Glycoproteins of the Platelet Plasma Membrane
1985The glycoproteins of the platelet plasma membrane, in common with those of the plasma membranes of other cells, have an important role in the interaction of platelets with their environment and in particular in the platelet’s function of hemostasis.
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On the role of the major platelet membrane glycoproteins in platelet adhesion to collagen
Thrombosis Research, 1981Abstract The effect of modification of intact rabbit platelets with chymotrypsin, trypsin or thrombin on platelet adhesion to collagen fibers was determined. Experiments were performed in vitro with washed platelets suspended in a medium containing EGTA to prevent platelet aggregation.
F. A. Meyer, J Lahav
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Structure and function of platelet membrane glycoproteins [PDF]
Platelets are involved in a variety of cellular interactions that occur during the hemostatic and inflammatory responses to tissue injury. These include adhesion to extracellular matrix proteins (e.g. von Willebrand factor, collagen, fibronectin, vitronectin, laminin), homotypic interaction with each other to form a platelet plug, and heterotypic ...
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Expression of platelet parameters and platelet membrane glycoproteins in childhood Burkitt lymphoma
Leukemia Research, 2019Platelet activation and functional changes in some haematological malignancies have been investigated with little or no known documentation on Burkitt lymphoma (BL). Abnormalities of platelets contribute to either haemorrhage or thrombotic episodes which are life-threatening in patients with BL.
Renate Asare +10 more
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Membrane glycoproteins of endothelial cells and platelets
1987Considerable evidence now supports an active role for vascular endothelial cells in the initiation and control of various physiological and pathophysiological processes including hemostasis, thrombosis, inflammation and immunological processes. Several events associated with these processes occur at the endothelial cell plasma membrane level.
J. Zandbergen-Spaargaren +3 more
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Thrombosis Research, 1989
Human platelets contain a single membrane glycoprotein which is susceptible to thrombin proteolysis, glycoprotein V. We have purified 1 mg of glycoprotein V from 10(13) platelets using a combination of gel filtration, hydroxylapatite and ion-exchange chromatographies. Glycoprotein V has a blocked amino-terminus.
Rasheeda S. Zafar, Daniel A. Walz
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Human platelets contain a single membrane glycoprotein which is susceptible to thrombin proteolysis, glycoprotein V. We have purified 1 mg of glycoprotein V from 10(13) platelets using a combination of gel filtration, hydroxylapatite and ion-exchange chromatographies. Glycoprotein V has a blocked amino-terminus.
Rasheeda S. Zafar, Daniel A. Walz
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Regulation of platelet membrane levels of glycoprotein VI by a platelet-derived metalloproteinase
Blood, 2004Thrombosis can be initiated when activated platelets adhere to injured blood vessels via the interaction of subendothelial collagen with its platelet receptor, glycoprotein (GP) VI. Here we observed that incubation of platelets with convulxin, collagen, or collagen-related peptide (CRP) resulted in GPVI signaling-dependent loss of surface GPVI and the ...
Jane Frances Arthur +9 more
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Platelet membrane glycoprotein changes during the preparation and storage of platelet concentrates
Transfusion, 1988Previous studies of platelet membrane glycoproteins during blood bank storage have reported conflicting results. This study assessed two major plasma membrane glycoproteins (GP Ib and GP IIb), an alpha‐ granule membrane protein (GMP‐140), and the concentration of platelet membrane microparticles in cell‐free plasma during routine hospital blood bank ...
Robert Heinz +2 more
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The Immunogenicity of Platelet Membrane Glycoproteins
Transfusion Medicine Reviews, 1987Diane J. Nugent +11 more
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MEMBRANE GLYCOPROTEINS AND HUMAN PLATELET FUNCTION
British Journal of Haematology, 1978Jacques P. Caen, Alan T. Nurden
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