Results 151 to 160 of about 5,003 (295)
Globally, sickle cell disease (SCD) is the most common inherited haemoglobinopathy. The highest burden of SCD is encountered in low‐ and middle‐income countries (LMICs), most of which lack the resources to contend with the disease. Blood transfusion remains central to the emergent treatment and prevention of complications of SCD.
Jeremy W. Jacobs+13 more
wiley +1 more source
A Computational Approach for Modeling Platelet Adhesion Dynamics on Thrombogenic Surfaces [PDF]
Platelet adhesion and aggregation are essential for primary hemostasis, forming a clot that quickly stops initial bleeding. Despite this critical role, the dynamic interactions of platelet receptors with exposed collagen and von Willebrand factor (vWF) at the injury site and how these interactions influence thrombus formation under varying blood flow ...
arxiv
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Myeloid neoplasm inspired intensive therapy in VEXAS syndrome: A single‐centre experience
Summary There is still no standard of care and unmet medical needs in refractory/advanced VEXAS (vacuoles in myeloid progenitors, E1 ubiquitin activating enzyme, X‐linked, autoinflammatory manifestations and somatic) syndrome with or without associated haematological neoplasm.
Maël Heiblig+5 more
wiley +1 more source
Cytokine Release Syndrome Is an Independent Risk Factor Associated With Platelet Transfusion Refractoriness After CAR-T Therapy for Relapsed/Refractory Acute Lymphoblastic Leukemia. [PDF]
Liu Y+9 more
europepmc +1 more source
Transfusion of platelet concentrates remains the first-line therapy for Glanzmann thrombasthenia in case of bleeding or preparation for surgery. However, development of antibodies to platelet glycoprotein (Gp) IIb/IIIa complex or human leukocyte ...
Omer Devecioğlu+5 more
doaj
Outcomes of Melflufen Treatment in Patients With Relapsed/Refractory Multiple Myeloma
ABSTRACT Objective Melphalan flufenamide (melflufen) plus dexamethasone is fully approved in Europe for patients with relapsed/refractory multiple myeloma (RRMM) with ≥ 3 prior lines of therapy. We analyzed the efficacy and safety of melflufen in the real‐world setting.
Shahrier Hossain+9 more
wiley +1 more source
Convalescent Plasma for Ebola Virus Disease [PDF]
Fischer, William+2 more
core +4 more sources
Two dogs with haematuria and frequent urination were referred to our veterinary hospital. They were diagnosed with lower urinary tract carcinoma based on urine cytology and BRAF mutation testing. Transarterial embolisation was performed because of persistent haematuria.
S. Jeon, G. Lee, N. Lee, D. Chang
wiley +1 more source
[Incidence and clinical significance of platelet transfusion refractoriness after allogeneic hematopoietic stem cell transplantation in patients with chronic myelomonocytic leukemia]. [PDF]
Zhao C+8 more
europepmc +1 more source