LncRNA-MEG3 Mediated Diabetic Cerebral Ischemia-Reperfusion Injury-Induced Apoptosis via Modulating Interaction Between Annexin A2 and Akt in Mitochondria. [PDF]
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Patient-derived xenografts from circulating cancer stem cells as a preclinical model for personalized pancreatic cancer research. [PDF]
Wagner BJ +17 more
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Integrin mutations in blistering skin diseases and related genetically engineered mouse models. [PDF]
Dhulipalla S, Longmate WM.
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Linking Cell Architecture to Mitochondrial Signaling in Neurodegeneration: The Role of Intermediate Filaments. [PDF]
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Autosomal recessive epidermolysis bullosa simplex due to compound heterozygous mutations in the <i>DST</i> gene: the first Italian case and literature review. [PDF]
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Prechova et al. introduce the giant cytoskeletal crosslinker protein plectin.
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Plectin: A Cytolinker by Design
Biological Chemistry, 1999AbstractPlectin is a cytoskeletal protein of > 500 kDa that forms dumbbell-shaped homodimers comprising a central parallel α-helical coiled coil rod domain flanked by globular domains, thus providing a molecular backbone ideally suited to mediate the protein's interactions with an array of other cytoskeletal elements.
Steinböck, Ferdinand, Wiche, Gerhard
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Interaction of plectin and intermediate filaments
Journal of Dermatological Science, 2012Plectin, a member of the plakin family proteins, is a high molecular weight protein that is ubiquitously expressed. It acts as a cytolinker for the three major components of the cyotoskeleton, namely actin microfilaments, microtubules and intermediate filaments.The aim of our experiments was to identify new binding sites for intermediate filaments on ...
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