Results 101 to 110 of about 4,450 (185)

Cytolinker Cross-talk: Periplakin N-terminus Interacts with Plectin to Regulate Keratin Organisation and Epithelial Migration

, 2007
Periplakin is a cytoskeletal linker protein that participates in the assembly of epidermal cell cornified envelope and regulates keratin organisation in simple epithelial cells.
McInroy, Lorna, Maatta, Arto, Boczonadi, Veronika   +2 more
core   +1 more source

Plectin isoform P1b and P1d deficiencies differentially affect mitochondrial morphology and function in skeletal muscle

, 2016
Plectin, a versatile 500-kDa cytolinker protein, is essential for muscle fiber integrity and function. The most common disease caused by mutations in the human plectin gene, epidermolysis bullosa simplex with muscular dystrophy (EBS-MD), is characterized
Wiche, Gerhard, Kuznetsov, Andrey V., Grimm, Michael, Zeöld, Anikó, Winter, Lilli, Fischer, Irmgard   +5 more
core   +1 more source

Reconstitution of cytolinker-mediated crosstalk between actin and vimentin

European Journal of Cell Biology
Cell shape and motility are determined by the cytoskeleton, an interpenetrating network of actin filaments, microtubules, and intermediate filaments. The biophysical properties of each filament type individually have been studied extensively by cell-free
Irene Istúriz Petitjean, Quang D. Tran, Angeliki Goutou, Zima Kabir, Gerhard Wiche, Cécile Leduc, Gijsje H. Koenderink   +6 more
doaj   +1 more source

Specificity of binding of the plectin actin-binding domain to β4 integrin

, 2003
Plectin is a major component of the cytoskeleton and links the intermediate filament system to hemidesmosomes by binding to the integrin β4 subunit. Previously, a binding site for β4 was mapped on the actin-binding domain (ABD) of plectin and binding of ...
Litjens, Sandy H.M., Van Wilpe, Sandra, Kuikman, Ingrid, De Pereda, José M., Koster, Jan, Sonnenberg, Arnoud   +5 more
core   +1 more source

Filamin A in the ovary: a mediator of granulosa cell functions

Reproduction and Fertility
Filamin A (FLNA) regulates the mechanical properties and shape of cells by cross-linking actin filaments orthogonally. It also serves as a scaffold for numerous interacting proteins, thereby coordinating cell differentiation and morphogenesis.
Yuhao Jiang, Karolina M Caban, Jan B Stöckl, Thomas Fröhlich, Gregory A Dissen, Dieter Berg, Ulrike Berg, Artur Mayerhofer, Annette Müller-Taubenberger, Harald Welter   +9 more
doaj   +1 more source

Effects of Oxidative Stress on The Cytoskeletal Crosslinker Protein, Plectin

, 2005
Oxidative stress has been implicated in the onset of various diseases, including renal failure and neurodegenerative diseases. Increasing number of studies suggest the involvement of multiple processes in the pathogenesis of cell injury during oxidative ...
Manikwar, Prakash
core  

Plectin [PDF]

, 2020
openaire   +1 more source

Structure of the plakin domain of plectin

, 2016
Resumen del póster presentado al 22nd IUBMB y al 37th FEBS, celebrados en Sevilla (España) del 4 al 9 de septiembre de 2012.Plectin is a member of the plakin family of proteins that cross-links components of the cytoskeleton and link them to membrane ...
Ortega, Esther, Martínez Buey, Rubén, Pereda, José M. de   +2 more
core  

Plectin Serves as an Autoantigen in Paraneoplastic Pemphigus [PDF]

Journal of Investigative Dermatology, 1999
Aho, Sirpa, Mahoney, Mŷ G., Uitto, Jouni   +2 more
openaire   +2 more sources

Expression and localisation of intermediate filaments in plectin-defiucient muscles

Plectin ist ein 500 kDa großes multifunktionales Zytolinker-Protein und spielt eine äußerst wichtige Rolle im Zytoskelett, da es die korrekte Organisation von Zellen gewährleistet.
Petsch, Jonas
core