Results 101 to 110 of about 7,348 (200)
N-terminal α Dystroglycan (αDG-N): A Potential Serum Biomarker for Duchenne Muscular Dystrophy [PDF]
, 2018 Biological Sciences: 2nd Place (The Ohio State University Edward F. Hayes Graduate Research Forum)Background: Duchenne Muscular Dystrophy (DMD) is a severe, progressive, neuromuscular disorder of childhood.
Crowe, Kelly E.
core +1 more source
Small Science, Volume 5, Issue 11, November 2025.Cancer and neurodegeneration share interconnected nanosized molecular pathways. Novel nanobiomedicine approaches promise targeted biomarkers and therapies. Atomic force microscopy (AFM) is invaluable to characterize nanosized biomolecular processes beyond imaging.
Carlos Marcuello +5 more
wiley +1 more source
Exploration, Volume 5, Issue 5, October 2025.This review emphasizes the critical role of autophagy in cancer treatment, highlighting the development of autophagy‐targeting nanomedicines and their applications in combination therapies. It explores how nanoplatforms can effectively regulate autophagy, underscoring the potential of integrating autophagy modulation with other treatment strategies to ...
Zhouyi Sun +10 more
wiley +1 more source
Epidermolysis bullosa simplex: genotype-phenotype correlations
Vestnik Dermatologii i VenerologiiEpidermolysis bullosa simplex (EBS) includes a group of diseases characterized by varying severity, possible damage to visceral organs, and various outcomes ranging from complete regression of the rash to death. The initial clinical manifestations of EBS
Vadim V. Chikin, Arfenia E. Karamova
doaj +1 more source
Vimentin intermediate filaments control actin stress fiber assembly through GEF-H1 and RhoA [PDF]
, 2017 The actin and intermediate filament cytoskeletons contribute to numerous cellular processes, including morphogenesis, cytokinesis and migration. These two cytoskeletal systems associate with each other, but the underlying mechanisms of this interaction ...
Cheng, Fang +6 more
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PKD2 and RSK1 Regulate Integrin β4 Phosphorylation at Threonine 1736.
PLoS ONE, 2015 The integrin α6β4, a major component of hemidesmosomes (HDs), stabilizes keratinocyte cell adhesion to the epidermal basement membrane through binding to the cytoskeletal linker protein plectin and association with keratin filaments.
Lisa Te Molder, Arnoud Sonnenberg
doaj +1 more source
Multimedia distributions, bioaccumulation, and trophic transfer of microcystins in the Geum River Estuary, Korea: Application of compound-specific isotope analysis of amino acids [PDF]
, 2019 To determine distributions, bioaccumulation, and trophic transfer of freshwater cyanobacterial toxins such as microcystins (MCs), surface water, suspended solids, sediments, and coastal organisms were collected from seven stations in inner and outer ...
신경훈
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Plectin contributes to mechanical properties of living cells
American Journal of Physiology-Cell Physiology, 2009 Plectin is a 500-kDa cross-linking protein that plays important roles in a number of cell functions including migration and wound healing. We set out to characterize the role of plectin in mechanical properties of living cells. Plectin−/− cells were less stiff than plectin+/+ cells, but the slopes of the two power laws in response to loading ...
Na, Sungsoo +7 more
openaire +4 more sources
Crystal structure of a hemojuvelin-binding fragment of neogenin at 1.8 Å [PDF]
, 2011 Neogenin is a type I transmembrane glycoprotein with a large ectodomain containing tandem immunoglobulin-like and fibronectin type III (FNIII) domains. Closely related to the tumor suppressor gene DCC, neogenin functions in critical biological processes ...
Bjorkman, Pamela J. +2 more
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CellsIn muscle cells subjected to mechanical stimulation, LINC complex and cytoskeletal proteins are basic to preserve cellular architecture and maintain nuclei orientation and positioning. In this context, the role of lamin A/C remains mostly elusive.
Vittoria Cenni +7 more
doaj +1 more source