Results 41 to 50 of about 50,540 (257)
Function and evolution of microRNAs in eusocial Hymenoptera
Frontiers in Genetics, 2015 The emergence of eusociality (true sociality) in several insect lineages represents one of the most successful evolutionary adaptations in the animal kingdom in terms of species richness and global biomass.
Eirik eSovik +2 more
doaj +1 more source
G3: Genes, Genomes, Genetics, 2020 Plant breeding leads to the genetic improvement of target traits by selecting a small number of genotypes from among typically large numbers of candidate genotypes after careful evaluation.
Elie Raherison +6 more
doaj +1 more source
What is Antagonistic Pleiotropy?
, 2018 Antagonistic Pleiotropy has been the dominant theory for evolution of aging since it was first proposed 60 years ago. Indeed, examples of pleiotropy have been observed, but there are also many examples of mutations that lead to longer lifespan without ...
Josh Mitteldorf
core +2 more sources
eLife, 2021 Cooperation, paying a cost to benefit others, is widespread. Cooperation can be promoted by pleiotropic ‘win-win’ mutations which directly benefit self (self-serving) and partner (partner-serving).
Samuel Frederick Mock Hart +2 more
doaj +1 more source
Emerging infectious disease selects for darker plumage coloration in greenfinches
Frontiers in Ecology and Evolution, 2014 Outbreaks of emerging infectious disease offer a unique chance to study viability selection in action in short time windows. Finch trichomonosis, caused by a protozoan Trichomonas gallinae emerged in Great Britain in 2005 and led to epidemic mortality ...
Marju eMänniste, Peeter eHõrak
doaj +1 more source
The evolution of pleiotropy promotes cooperation.
, 2022 Heatmaps show average trait values among the global population of cells (across all groups) at steady state in our model. Results are shown for 3 group sizes (increasing from top to bottom).
Kevin R. Foster (8893457) +4 more
core +1 more source
Pleiotropy as the Mechanism for Evolving Novelty: Same Signal, Different Result
Biology, 2015 In contrast to the probabilistic way of thinking about pleiotropy as the random expression of a single gene that generates two or more distinct phenotypic traits, it is actually a deterministic consequence of the evolution of complex physiology from the ...
John S. Torday
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2023 Immune checkpoint inhibitors (ICIs) and Janus kinase inhibitors (JAKis) have raised concerns over serious unexpected cardiovascular adverse events.
Nhu Ngoc Le +4 more
doaj +1 more source
Horizontal pleiotropy statistics of two-sample Mendelian randomization analyses.
, 2022 Horizontal pleiotropy statistics of two-sample Mendelian randomization analyses.
Daniel Jönsson (10751687) +6 more
core +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source