Results 101 to 110 of about 7,658 (197)
Dysregulated expression and function of Plexin-β1 in ovarian cancers
, 2010 BACKGROUND: Ovarian cancer has a tendency to spread within the peritoneal cavity early in the disease course. Understanding the metastatic pathways of ovarian cancer is thus of high importance for devising ovarian cancer treatment. Plexin-B1 is a cognate
Ngan, HYS +3 more
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The Role of Plexin-B2 in the Immune System
, 2010 Plexins and semaphorins are a family of transmembrane proteins that mediate diverse roles such as cell-cell contact, cell adhesion, cell movement, and cell response.
Roney, Kelly E.
core +1 more source
Signaling mechanisms of plexin -B1: A receptor for semaphorin 4D.
, 2005 The adult nervous system is an intricate map of neurons that forms precise connections to allow for the functioning of the human body. During development of the nervous system, neurons send out projections to sense the environment.
Aurandt, Jennifer Lynn
core
, 2001 Plexins are receptors implicated in mediating signaling by semaphorins, a family of axonal chemorepellents. The role of specific plexins in mediating semaphorin function in vivo has not, however, yet been examined in vertebrates.
Yaron, Avraham +5 more
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NOVEL MEMBERS OF THE PLEXIN FAMILY AND USES THEREOF
, 2000 The invention provides methods and compositions related to novel plexins. The polypeptides may be produced recombinantly from transformed host cells and from the disclosed plexin encoding nucleic acids or purified from human cells. The invention provides
TAMAGNONE Luca
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Plexin-B1 signalling promotes androgen receptor translocation to the nucleus
, 2016 Semaphorins and their receptors plexins have diverse roles in many cancers affecting tumour growth, metastasis and angiogenesis. Plexin-B1, the receptor for semaphorin4D (Sema4D), has been implicated in prostate cancer where mutation of the gene and ...
Williamson, M. +2 more
core +1 more source
Structural Bases of Plexin Signal Transduction
, 2017 Plexins are a family of transmembrane receptors for the Semaphorin family of repulsive axon guidance molecules. Plexin mediated signal transduction is critical for a variety of cellular processes including regulation of adhesion and actin organization ...
Pascoe, Heath Garrick
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Abstract 3183: Dysregulated expression and function of Plexin-B1 in ovarian cancers
, 2010 Background: Ovarian cancer has a tendency to spread within the peritoneal cavity early in the disease course. Understanding the metastatic pathways of ovarian cancer is thus of high importance for devising ovarian cancer treatment. Plexin-B1 is a cognate
Wong GW Oscar +3 more
core +1 more source
, 2020 The Semaphorin-Plexin signaling is important for regulating axon guidance. Binding of Semaphorin to the Plexin receptor induces the dimerization of Plexin and stimulates its cytoplasmic GAP activity towards Rap, resulting in cytoskeleton re-organization.
Kuo, Yi-Chun
core
, 2011 Plexin-A4 is a receptor for sema6A and sema6B and associates with neuropilins to transduce signals of class-3 semaphorins. We observed that plexin-A1 and plexin-A4 are required simultaneously for transduction of inhibitory sema3A signals and that they ...
Boaz Kigel +4 more
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