Results 121 to 130 of about 4,153 (193)

Tipping the balance: synthesis and evaluation of centrinone-based degraders of polo-like kinase 4. [PDF]

RSC Chem Biol
Kovacevic A, Salim A, Borges C, Meraldi P, Hoogendoorn S.   +4 more
europepmc   +1 more source

Migrasome-mediated clearance of PLK4: a novel mechanism for centrosome homeostasis and tumor targeting. [PDF]

EBioMedicine
Zhao Z, Song Y.
europepmc   +1 more source

The Trifecta of Polo-Like Kinases, Cancer, and the Immune System: Emerging Intersections and Therapeutic Insights. [PDF]

Mol Cancer Res
Jaiswal T, Shirley CA, Rastogi I, Chhabra G, Chang H, Ahmad N.   +5 more
europepmc   +1 more source

Stress adaptation pathways and HA-CD44 signaling maintain the survival of pancreatic cancer cells with centrosome amplification. [PDF]

Cell Commun Signal
Ozcan SC, Goksel E, Kalkan BM, Cicek E, Kanevetci B, Acilan C.   +5 more
europepmc   +1 more source

McIdas localizes to centrioles and controls centriole numbers through PLK4-dependent phosphorylation. [PDF]

EMBO Rep
Arbi M, Skamnelou M, Koufoudaki L, Bakali V, Bournaka S, Zitouni S, Tsaridou S, Karayel O, Vasilopoulou CG, Tsika AC, Giakoumakis NN, Preza O, Spyroulias GA, Mann M, Bettencourt-Dias M, Taraviras S, Lygerou Z.   +16 more
europepmc   +1 more source

Targeting KIFC1 to disrupt centrosome clustering and trigger anaphase catastrophe in small-cell lung cancer. [PDF]

JCI Insight
Nakagawa N, Toda M, Kunita A, Horie M, Tokunaga M, Ikushima H, Ka M, Iida T, Shigeoka M, Ito Y, Ando T, Watanabe K, Ota Y, Liu X, Dmitrovsky E, Kage H, Kawakami M.   +16 more
europepmc   +1 more source

Identification of Central Regulatory Hubs in Pupal Diapause of <i>Helicoverpa armigera</i> Using Weighted Gene Co-Expression Network Analysis and Multiscale Embedded Network Analysis. [PDF]

Insects
Song Z, Liu X, Cao J, Wang Y.
europepmc   +1 more source

Distinct pathophysiological mechanisms of CEP152 variants in microcephaly and brain abnormalities. [PDF]

EMBO Mol Med
Hamada N, AlAbdi L, Uehara T, Sasikarn L, Nishijo T, Suliman-Lavie R, Hashem MO, Alfadhel M, Alhefdhi S, Tabarki B, Alghamdi M, Iwamoto I, Takenouchi T, Kosaki K, Shifman S, Mizuno S, Ohno N, Alkuraya FS, Nagata KI.   +18 more
europepmc   +1 more source

Synthesis of PLK4 Inhibitor CFI-400945 [PDF]

Synfacts, 2015
openaire   +1 more source

Characterization of the Meiotic Niche of plk4 Heterozygous Mice

Nearly a tenth of couples struggle with infertility and of these cases half the issues are contributed by the males. Despite continued research, about a third of the cases of male infertility are idiopathic1.
Blendea, Patrick Armand
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