Results 101 to 110 of about 905 (118)

Plk4-induced Centriole Biogenesis in Human Cells [PDF]

, 2008
Kleylein-Sohn, Julia, Kleylein-Sohn, J.
core   +1 more source

TEC kinase stabilizes PLK4 to promote liver cancer metastasis

Cancer Letters, 2022
Aberrated PLK4 expression has been reported in different malignancies and causes centrosome amplification, aneuploidy, and genomic instability. However, the mechanism by which PLK4 is regulated in carcinogenesis remains not fully characterised.
Yick Pang Ching, Wallace Wing-Lim Chan
exaly   +2 more sources

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Role of Polo-like Kinases Plk1 and Plk4 in the Initiation of Centriole Duplication—Impact on Cancer

Cells, 2022
Íngrid Hoffmann
exaly  

Structure-based discovery of 1-(3-fluoro-5-(5-(3-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)phenyl)-3-(pyrimidin-5-yl)urea as a potent and selective nanomolar type-II PLK4 inhibitor

European Journal of Medicinal Chemistry, 2022
Tianxiao Wu, Huali Yang, Yixiang Sun
exaly  

Structural and Functional Analyses of the FAM46C/Plk4 Complex

Structure, 2020
Guoming Gao, Guijun Shang, Xuewu Zhang   +2 more
exaly  

Design, synthesis, and biological evaluation of novel pyrazolo [3,4-d]pyrimidine derivatives as potent PLK4 inhibitors for the treatment of TRIM37-amplified breast cancer

European Journal of Medicinal Chemistry, 2022
Dongmei Zhao, Yu Sun, Tianxiao Wu
exaly  

PLK4 is a determinant of temozolomide sensitivity through phosphorylation of IKBKE in glioblastoma

Cancer Letters, 2019
Lei Han, Zengguang Wang, Guangxiu Wang   +2 more
exaly  

PLK4: a promising target for cancer therapy

Journal of Cancer Research and Clinical Oncology, 2019
Xin Wang, Yi Zhao
exaly  

Plk4 Regulates Centriole Asymmetry and Spindle Orientation in Neural Stem Cells

Developmental Cell, 2019
Renata Basto, Yuu Kimata, Maddalena Nano   +2 more
exaly  

A non‐canonical function of Plk4 in centriolar satellite integrity and ciliogenesis through PCM 1 phosphorylation

EMBO Reports, 2016
Takashi Toda, Bram Snijders, Karin Barnouin   +2 more
exaly