Results 81 to 90 of about 201,548 (273)
Induced pluripotent stem cells: advances to applications
Stem Cells and Cloning: Advances and Applications, 2009 Timothy J Nelson1, Almudena Martinez-Fernandez1, Satsuki Yamada1, Yasuhiro Ikeda2, Carmen Perez-Terzic1, Andre Terzic11Marriott Heart Disease Research Program, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA; 2Department of ...
Timothy J Nelson +3 more
doaj
Stem Cells International, 2016 A mere 9 years have passed since the revolutionary report describing the derivation of induced pluripotent stem cells from human fibroblasts and the first in-patient translational use of cells obtained from these stem cells has already been achieved ...
Aoife Gowran +7 more
doaj +1 more source
Measurements and System Identification for the Characterization of Smooth Muscle Cell Dynamics [PDF]
2024 IEEE International Symposium on Medical Measurements and
Applications (MeMeA)Biological tissue integrity is actively maintained by cells. It is essential to comprehend how cells accomplish this in order to stage tissue diseases. However, addressing the complexity of a cell's system of interrelated mechanisms poses a challenge.
arxiv +1 more source
The Role of Silicon Technology in Organ‐On‐Chip: Current Status and Future Perspective
Advanced Materials Technologies, EarlyView.This review explores the potential of silicon micro‐nanofabrication technologies in advancing organ‐on‐chip systems. The integration of actuation and sensing modalities, highlight emerging technologies is discussed for combining silicon‐based and polymer‐based components, and emphasize the need for robust, high‐throughput, and customizable organ‐on ...
Frøydis Sved Skottvoll +2 more
wiley +1 more source
International Journal of Organ Transplantation Medicine, 2015 Background: In regenerative medicine, use of each of the mesenchymal stem cells derived from bone marrow, cord blood, and adipose tissue, has several cons and pros.
T Foroutan +4 more
doaj
Identification of Biomarkers Driving Blood Cell Development [PDF]
arXiv, 2019 A blood cell lineage consists of several consecutive developmental stages from the pluripotent or multipotent stem cell to a particular stage of terminally differentiated cells. There is considerable interest in identifying the key regulatory genes that govern blood cell development from the gene expression data without considering the underlying ...
arxiv
DNA Torsion-based Model of Cell Fate Phase Transitions [PDF]
arXiv, 2020 All stem cell fate transitions, including the metabolic reprogramming of stem cells and the somatic reprogramming of fibroblasts into pluripotent stem cells, can be understood from a unified theoretical model of cell fates. Each cell fate transition can be regarded as a phase transition in DNA supercoiling.
arxiv
Advances in Microfluidic Cochlea‐On‐A‐Chip
Advanced Science, EarlyView.This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen +10 more
wiley +1 more source
Editorial: The pathogenesis of aplastic anemia: a defective pluripotent hematopoietic stem cell with inappropriate balance of differentiation and self-replication [PDF]
, 1976 DR Boggs, S. S. Boggs
openalex +1 more source
Ultralow‐Dimensionality Reduction for Identifying Critical Transitions by Spatial‐Temporal PCA
Advanced Science, EarlyView.The proposed spatial‐temporal principal component analysis (stPCA) method analytically reduces high‐dimensional time‐series data to a single latent variable by transforming spatial information into temporal dynamics. By preserving the temporal properties of the original data, stPCA effectively identifies critical transitions and tipping points.
Pei Chen +6 more
wiley +1 more source