Results 111 to 120 of about 46,902 (263)

Old data, new tricks: Comprehensive computational analysis of 10 years of multi‐center EuroFlow acute myeloid leukemia diagnostic immunophenotypic data

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Acute myeloid leukemia (AML) is characterized by high genotypic and immunophenotypic heterogeneity. We collected an extensive dataset containing 5366 flow cytometry files from 885 AML patients, stained with the EuroFlow acute leukemia orientation tube (ALOT) and AML/MDS panel, acquired in a standardized way at eight centers over a period of 10 
Sarah Bonte, Rosan Olsman, Sofie Van Gassen, Sergio Matarraz, Neus Villamor, Stefan Nierkens, Paula Fernandez, Elaine Sobral da Costa, Carmen‐Mariana Aanei, Alberto Orfao, Jacques J. M. van Dongen, Yvan Saeys, Mattias Hofmans, Vincent H. J. van der Velden   +13 more
wiley   +1 more source

Insight into Metabolic 1H-MRS Changes in Natalizumab Induced Progressive Multifocal Leukoencephalopathy Brain Lesions

Frontiers in Neurology, 2017
BackgroundProgressive multifocal leukoencephalopathy (PML) is a severe complication of immunosuppressive therapies, especially of natalizumab in relapsing–remitting multiple sclerosis (MS). Metabolic changes within PML lesions have not yet been described
Ruth Schneider, Barbara Bellenberg, Robert Hoepner, Gisa Ellrichmann, Ralf Gold, Carsten Lukas   +5 more
doaj   +1 more source

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini, Mallorie P. Jenne, Michael L. Piacentino   +2 more
wiley   +1 more source

TRIM19/PML Restricts HIV Infection in a Cell Type-Dependent Manner

Viruses, 2015
The promyelocytic leukemia protein (PML) is the main structural component of the nuclear matrix structures termed nuclear domain 10 (ND10) or PML nuclear bodies (PML-NBs).
Tanja Kahle, Bianca Volkmann, Kristin Eissmann, Alexandra Herrmann, Sven Schmitt, Sabine Wittmann, Laura Merkel, Nina Reuter, Thomas Stamminger, Thomas Gramberg   +9 more
doaj   +1 more source

Revisiting promyelocytic leukemia protein targeting by human cytomegalovirus immediate-early protein 1.

PLoS Pathogens, 2020
Promyelocytic leukemia (PML) bodies are nuclear organelles implicated in intrinsic and innate antiviral defense. The eponymous PML proteins, central to the self-organization of PML bodies, and other restriction factors found in these organelles are ...
Christina Paulus, Thomas Harwardt, Bernadette Walter, Andrea Marxreiter, Marion Zenger, Edith Reuschel, Michael M Nevels   +6 more
doaj   +1 more source

IDENTIFICATION AND CHARACTERIZATION OF PROMYELOCYTIC LEUKEMIA (PML)-ISOFORM 1 SPECIFIC PROTEIN-PROTEIN INTERACTIONS

, 2011
Loss of the promyelocytic leukemia (PML) protein is associated with genomic instability/cancer. There are several isoforms of the PML protein that localize in PML nuclear bodies (PML NBs).
Tse, Brenda
core  

A Green Scalable Method to Prepare Zr Oxide Dicarboxylate Metal–Organic Frameworks

European Journal of Inorganic Chemistry, EarlyView.
A greener approach for large‐scale synthesis of MIL‐140(Zr) family for cultural heritage preservation. We report the synthesis of a series of isoreticular hydrophobic microporous zirconium dicarboxylate metal–organic frameworks (MOFs), MIL‐140(Zr)s, under green ambient pressure conditions.
Debanjan Chakraborty, Sanchari Dasgupta, Oleksii Kolmykov, Maria Inês Severino Neves, Vanessa Pimenta, Abeer Mohtar, Cátia Freitas, Iurii Dovgaliuk, Moises L. Pinto, Georges Mouchaham, Farid Nouar, Christian Serre   +11 more
wiley   +1 more source

The clinical features of PML

Cleveland Clinic Journal of Medicine, 2011
The symptoms associated with progressive multifocal leukoencephalopathy (PML) reflect the location of pathologic brain lesions. These symptoms include visual deficits, cognitive impairment, and motor weakness; in patients with acquired immunodeficiency syndrome (AIDS), presenting signs can also include gait disturbance, dysarthria, dysphasia, and ...
openaire   +2 more sources

Venous blood lactate concentration as a predictor of intestinal viability in horses with acquired indirect inguinal hernia

Equine Veterinary Journal, EarlyView.
Abstract Background Acquired indirect inguinal hernia represents a life‐threatening emergency. Therapeutic decision‐making largely depends on intestinal viability, for which specific predictive parameters (such as venous lactate) have not been evaluated.
Raquel Rivero‐García, Cristina Andreu‐Vázquez, Beatriz Fuentes‐Romero, Pablo Fernández‐Hernández, María Luisa Rodríguez‐Pozo, Ignacio Aguilar Sebastián, Salvador Termes Soto, Mercedes Martínez Gallardo, Manuel Iglesias‐García   +8 more
wiley   +1 more source

Influence of Drain and Operational Parameters on Backwash Cleaning Efficiency in a Commercial Sand Filter Model

Irrigation and Drainage, EarlyView.
ABSTRACT Some studies have demonstrated the influence of the drainage system design on the hydraulic behaviour and on the expansion of the filter bed during the backwashing process, with a presumed effect on removal efficiency. The objective was to evaluate the influence of the drainage system design of a commercial sand filter model, the operating ...
Mádilo Lages Vieira Passos, Fábio Ponciano de Deus, Evelise Roman Corbalan Góis Freire, Michael Silveira Thebaldi, Victor Buono da Silva Baptista   +4 more
wiley   +1 more source