Results 111 to 120 of about 42,451 (299)

Performance of PML diagnostic criteria in natalizumab-associated PML: data from the Dutch-Belgian cohort [PDF]

, 2019
OBJECTIVE: To test the current progressive multifocal leukoencephalopathy (PML) diagnostic criteria by applying them to patients previously diagnosed with natalizumab (NTZ)-associated PML in a real-world clinical setting. METHODS: Patients from the Dutch-
Killestein, J, Uitdehaag, BMJ, Uitdehaag, Bernard M J, Wattjes, Mike P, Warnke, Clemens, Killestein, Joep, Wijburg, MT, Barkhof, F, Wattjes, MP, Barkhof, Frederik, Wijburg, Martijn T, Warnke, C   +11 more
core   +1 more source

Wearable Real‐Time Translation in Rhinology: A Comparative Study of Accuracy and Efficiency

International Forum of Allergy &Rhinology, EarlyView.
Emma J. Anisman, Nickolas Pudik, Laura Palacio‐Morales, Abdulghafoor Alani, Yanmin Qu, Chang Liu, Agustina Arce, Shin Heng Teresa Chan, Benjamin Bitner, Marc Rosen, Gurston Nyquist, Elina Toskala, Mindy Rabinowitz   +12 more
wiley   +1 more source

Development and Validation of the Body Neutrality Questionnaire

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Body neutrality has emerged as an alternative framework within the positive body image literature. This study developed the Body Neutrality Questionnaire (BNQ), the first validated measure of body neutrality for young adults. Method An initial item pool was developed using expert consultation and focus group review.
Amelia Kimpton, Laura Edney, Charles Goya, Tracey D. Wade, Mia L. Pellizzer   +4 more
wiley   +1 more source

Validation of PML^−/− and PML^+/+ MEFs.

, 2013
(A) Western blot showing PML−/− MEFs do not express PML protein. (B) Semi-quantitative RT-PCR also indicated that PML−/− MEFs do not express PML. β-actin served as an internal control.
Elve Chen (392737), Jingyi Gan (392738), Yong Jia Liang (392734), Sing Wan Wong (392736), Kenneth Ka Ho Lee (384738), John Yeuk Hon Chan (392735), Mei Kuen Tang (392733), Hin Cheung Leung (392740), Hsiang Fu Kung (376115), Hua Wang (13530), Yao Yao (335996), Lihai Xiao (392739)   +11 more
core   +1 more source

Venous blood lactate concentration as a predictor of intestinal viability in horses with acquired indirect inguinal hernia

Equine Veterinary Journal, EarlyView.
Abstract Background Acquired indirect inguinal hernia represents a life‐threatening emergency. Therapeutic decision‐making largely depends on intestinal viability, for which specific predictive parameters (such as venous lactate) have not been evaluated.
Raquel Rivero‐García, Cristina Andreu‐Vázquez, Beatriz Fuentes‐Romero, Pablo Fernández‐Hernández, María Luisa Rodríguez‐Pozo, Ignacio Aguilar Sebastián, Salvador Termes Soto, Mercedes Martínez Gallardo, Manuel Iglesias‐García   +8 more
wiley   +1 more source

Post‐Translational Modifications of Key Proteins in Hematologic Malignancies: Carcinogenic Mechanisms, Biomarker Potential, and New Therapeutic Strategies

iLABMED, EarlyView.
This article reviews the pivotal role of post‐translational modifications of proteins in the development and progression of hematologic malignancies, and explores their clinical translation potential as novel biomarkers and therapeutic targets. ABSTRACT Post‐translational modifications (PTMs) of proteins have emerged as critical regulators in the ...
Yuxuan Han, Chaowei Zhang, Weiyi Yao, Qing Hong, Xinyu Tang, Yanan Zhu, Na Chen   +6 more
wiley   +1 more source

Treatment of natalizumab‐associated PML with filgrastim

Annals of Clinical and Translational Neurology, 2019
Objective There is no consensus on the treatment of progressive multifocal leukoencephalopathy (PML) occurring in multiple sclerosis (MS) patients treated with natalizumab (Nz). We report novel immune activating treatment with filgrastim of Nz‐associated
Dusan Stefoski, Roumen Balabanov, Rasha Waheed, Michael Ko, Igor J. Koralnik, Fabian Sierra Morales   +5 more
doaj   +1 more source

Immune Response in PML

, 2001
Progressive multifocal leukoencephalopathy (PML) is a fatal, demyelinating disease caused by JC virus (JCV) in patients with severe immunosuppression.
Petry, Harald, Young, Peter, Kaup, Franz Josef, Weber, Frank, Weber, Thomas, Goldmann, Claudia, Pickhardt, Marcus, Krämer, Marcus, Lüke, Wolfgang   +8 more
core   +1 more source

Holistic bone developing microenvironment engineered apoptotic extracellular vesicles recapitulate multidimensional developmental signatures in adult and senile bone repair

Interdisciplinary Medicine, EarlyView.
The developing bone was identified as an M2a‐like macrophage driven immune microenvironment with multidimensional developmental signatures. hME‐ApoEVs were successfully fabricated via stimulating the M2a‐like developing microenvironment in vitro and confirmed its recapitulation of developmental features.
Xiaoran Yu, Jieyun Xu, Yuan Zhao, Xinyu Guo, Hongcheng Chen, Junlong Xue, Yong Ao, Linjun Zhang, Xiaomeng Gao, Xueli Mao, Songtao Shi, Zetao Chen   +11 more
wiley   +1 more source

PML/TRIM19-Dependent Inhibition of Retroviral Reverse-Transcription by Daxx.

PLoS Pathogens, 2015
PML (Promyelocytic Leukemia protein), also known as TRIM19, belongs to the family of tripartite motif (TRIM) proteins. PML is mainly expressed in the nucleus, where it forms dynamic structures known as PML nuclear bodies that recruit many other proteins,
Jacques Dutrieux, Ghizlane Maarifi, Débora M Portilho, Nathalie J Arhel, Mounira K Chelbi-Alix, Sébastien Nisole   +5 more
doaj   +1 more source