Results 121 to 130 of about 100,358 (268)

Treatment of natalizumab‐associated PML with filgrastim

Annals of Clinical and Translational Neurology, 2019
Objective There is no consensus on the treatment of progressive multifocal leukoencephalopathy (PML) occurring in multiple sclerosis (MS) patients treated with natalizumab (Nz). We report novel immune activating treatment with filgrastim of Nz‐associated
Dusan Stefoski, Roumen Balabanov, Rasha Waheed, Michael Ko, Igor J. Koralnik, Fabian Sierra Morales   +5 more
doaj   +1 more source

Energy dependence of the entanglement entropy of composite boson (quasiboson) systems

, 2013
Bipartite composite boson (quasiboson) systems, which admit realization in terms of deformed oscillators, were considered in our previous paper from the viewpoint of entanglement characteristics.
Gavrilik, A. M., Mishchenko, Yu. A.
core   +1 more source

Validation of a Multiparametric, Automated, Macroarray‐Based Assay for the Detection of Autoantibodies in Autoimmune Liver Disease

Journal of Clinical Laboratory Analysis, EarlyView.
The assay exploited a multiparametric and fully automated device applied to CHORUS EVO to validate that the CHORUS Macroarray Liver Diseases kit is a novel procedure for detecting autoantibodies of AIH and PBC. The assay resulted as linear, accurate, sensitive, specific, and able to distinguish between PBC and AIH.
Luigi Raganelli, Tommaso Bandini, Matilde Ilacqua, Helena Cerutti, Alessandra Cartocci, Giulia Tesi, Andrea Ianniello, Thomas Massari, Mirko Berretti, Roberto Centini, Michele Norelli, Alessandra Brogi, Giampaola Pesce, Danilo Villalta, Brunetta Porcelli   +14 more
wiley   +1 more source

Mental health measures among adolescents in 12 low‐ and middle‐income countries: Measurement invariance and cross‐sectional analyses of Disrupting Harm survey data

JCPP Advances, EarlyView.
Abstract Background Nationally representative mental health data in adolescents from low‐ and middle‐income countries (LMICs) are scarce. This study aimed to examine mental health and wellbeing indicators amongst adolescents in 12 LMICs across Eastern and Southern Africa and Southeast Asia. Methods We conducted a secondary analysis of data involving 12,
Ariadna Albajara Sáenz, Sebastian Kurten, Jennifer Saxton, Daniel Kardefelt‐Winther, Tamsin Ford, Amy Orben, Simon R. White   +6 more
wiley   +1 more source

Dry‐Season Water Deficits in the Southwestern Amazon Under High Emissions

International Journal of Climatology, EarlyView.
Projected climatic water deficit in the study region indicates a longer and more intense dry season, with delays in the onset of the wet season under higher emission scenarios. These changes, particularly, pronounced under SSP5‐8.5, suggest increased ecological vulnerability and greater seasonal water stress.
Débora J. Dutra, Chris Jones, Richard A. Betts, Igor J. M. Ferreira, Luiz E. O. C. Aragão, Guilherme Mataveli, Henrique Leão, Breno I. Domingos, Beatriz F. Cabral, Philip M. Fearnside, Paulo M. L. A. Graça, Aurora M. Yanai, Celso H. L. Silva‐Junior, Thais P. de Medeiros, Ricardo Dalagnol, Daniel Braga, Vinícius Peripato, Chantelle Burton, Liana O. Anderson   +18 more
wiley   +1 more source

The PML-RAR alpha transcript in long-term follow-up of acute promyelocytic leukemia patients [PDF]

, 2001
Background and Objectives. Detection of PML-RAR alpha transcripts by RT-PCR is now established as a rapid and sensitive method for diagnosis of acute promyelocytic leukemia (APL), Although the majority of patients in longterm clinical remission are ...
Carrara, P, de Sousa, AB, Diamond, J, Foroni, L, Gameiro, P, Guimaraes, JE, Hoffbrand, AV, Mehta, AB, Parreira, A, Prentice, HG, Silva, AL, Vieira, S   +11 more
core  

Efficient First‐Principles Inverse Design of Nanolasers

Laser &Photonics Reviews, EarlyView.
This article introduces a first‐principles inverse‐design framework for nanolasers that directly incorporates nonlinear lasing physics. By unifying steady‐state ab‐initio laser theory (SALT) with topology optimization, it reveals how spatial hole burning, gain saturation, and cavity‐emitter coupling shape laser performance, enabling efficient discovery
Beñat Martinez de Aguirre Jokisch, Alexander Cerjan, Rasmus Ellebæk Christiansen, Jesper Mørk, Ole Sigmund, Steven G. Johnson   +5 more
wiley   +1 more source

Dipole‐Quadrupole Model and Multipole Analysis of Resonant Membrane Metasurfaces

Laser &Photonics Reviews, EarlyView.
Membrane metasurfaces, arrays of holes in a dielectric membrane, are appealing because they require no substrate and allow access to resonant near‐fields. However, developing a comprehensive theoretical description for them remains challenging. We introduce a semi‐analytical dipole‐quadrupole approach to analyze their resonant spectra at arbitrary ...
Izzatjon Allayarov, Andrey B. Evlyukhin, Antonio Calà Lesina   +2 more
wiley   +1 more source

Optical Skyrmions with Tunable or Reconfigurable Topology Using Spin‐Decoupled Metaoptics

Laser &Photonics Reviews, EarlyView.
The work introduces advanced optical elements capable of generating and dynamically reconfiguring complex light patterns known as optical skyrmions. By precisely shaping light polarization at the nanoscale, a single engineered metasurface can generate and manipulate robust and tunable polarization textures in an efficient and scalable way.
Andrea Vogliardi, Daniele Bonaldo, Simone Dal Zilio, Vittorio Apolloni, Filippo Romanato, Gianluca Ruffato   +5 more
wiley   +1 more source

PML/TRIM19-Dependent Inhibition of Retroviral Reverse-Transcription by Daxx.

PLoS Pathogens, 2015
PML (Promyelocytic Leukemia protein), also known as TRIM19, belongs to the family of tripartite motif (TRIM) proteins. PML is mainly expressed in the nucleus, where it forms dynamic structures known as PML nuclear bodies that recruit many other proteins,
Jacques Dutrieux, Ghizlane Maarifi, Débora M Portilho, Nathalie J Arhel, Mounira K Chelbi-Alix, Sébastien Nisole   +5 more
doaj   +1 more source