Results 121 to 130 of about 46,902 (263)

Repeated Exposure to a Hair Bleaching Mixture Alters cGAS–STING Pathway Transcripts in Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Hair bleaching products commonly contain ammonia and hydrogen peroxide, chemicals capable of generating reactive oxygen species (ROS). However, their effects on innate immune signaling pathways associated with DNA damage remain poorly understood.
Leticia Rodrigues Sampaio, Marjori Lima Boblitz Parente, Ronald Feitosa Pinheiro   +2 more
wiley   +1 more source

Impaired but now diagnosable: Combining analytic frameworks for incorporating symptom weighting in the classification of full‐threshold and subthreshold posttraumatic stress disorder

Journal of Traumatic Stress, EarlyView.
Abstract Individuals with subthreshold posttraumatic stress disorder (PTSD) often experience significant impairment yet face barriers to care (e.g., insurance denials and exclusion from clinical trials) due to strict Diagnostic and Statistical Manual of Mental Disorders (DSM)–based diagnostic criteria that rely entirely on symptom counts.
Krithika Prakash, Antonio A. Morgan‐López, Jordan A. Gette, Kelly R. Peck, Marilyn L. Piccirillo, Lissette M. Saavedra, Sudie E. Back, Therese K. Killeen, Sonya B. Norman, Stephen G West, Denise A. Hien, the Consortium on Addiction, Stress, and Trauma   +13 more
wiley   +1 more source

Treatment of natalizumab‐associated PML with filgrastim

Annals of Clinical and Translational Neurology, 2019
Objective There is no consensus on the treatment of progressive multifocal leukoencephalopathy (PML) occurring in multiple sclerosis (MS) patients treated with natalizumab (Nz). We report novel immune activating treatment with filgrastim of Nz‐associated
Dusan Stefoski, Roumen Balabanov, Rasha Waheed, Michael Ko, Igor J. Koralnik, Fabian Sierra Morales   +5 more
doaj   +1 more source

DNA-binding defective PML/RARA mutants disrupt PML nuclear bodies.

, 2014
NIH-3T3 cells (A and C) or mouse HPCs (B and D) were infected with retroviral constructs expressing wild type or the indicated mutant PML/RARA respectively.
Laurent Peres (614585), Hao Yuan (502114), Zhu Chen (3106), Xi Liu (142824), Jun Zhu (84054), Jun Zhou (6477), Saijuan Chen (275248), Hugues de The (5648671)   +7 more
core   +1 more source

Quantization of Polaritons Confined in Dielectric Structures

Laser &Photonics Reviews, EarlyView.
This study addresses the limitations of the Hopfield model of strong light‐matter coupling in the case of structured dieletrics. A method to derive quantum models in the polariton basis using Bogoliubov transformation and third quantization is introduced, demonstrating how to boost interaction strength and engineer nonlocal interactions for strongly ...
Amir Rahmani, Dogyun Ko, Maciej Dems, Andrzej Opala, Michał Matuszewski   +4 more
wiley   +1 more source

Validation of PML^−/− and PML^+/+ MEFs.

, 2013
(A) Western blot showing PML−/− MEFs do not express PML protein. (B) Semi-quantitative RT-PCR also indicated that PML−/− MEFs do not express PML. β-actin served as an internal control.
Elve Chen (392737), Jingyi Gan (392738), Yong Jia Liang (392734), Sing Wan Wong (392736), Kenneth Ka Ho Lee (384738), John Yeuk Hon Chan (392735), Mei Kuen Tang (392733), Hin Cheung Leung (392740), Hsiang Fu Kung (376115), Hua Wang (13530), Yao Yao (335996), Lihai Xiao (392739)   +11 more
core   +1 more source

Revealing the Resonant Physics of Open Photonic Time Crystals

Laser &Photonics Reviews, EarlyView.
ABSTRACT Photonic time crystals (PTCs) are media whose permittivity is modulated periodically in time, enabling momentum bandgaps and parametric amplification of light. Their realization at the nanoscale can revolutionize the study of light‐matter interactions.
Adrià Canós Valero, Sergei Gladyshev, David Globosits, Stefan Rotter, Egor A. Muljarov, Thomas Weiss   +5 more
wiley   +1 more source

PML/TRIM19-Dependent Inhibition of Retroviral Reverse-Transcription by Daxx.

PLoS Pathogens, 2015
PML (Promyelocytic Leukemia protein), also known as TRIM19, belongs to the family of tripartite motif (TRIM) proteins. PML is mainly expressed in the nucleus, where it forms dynamic structures known as PML nuclear bodies that recruit many other proteins,
Jacques Dutrieux, Ghizlane Maarifi, Débora M Portilho, Nathalie J Arhel, Mounira K Chelbi-Alix, Sébastien Nisole   +5 more
doaj   +1 more source

Extreme Optical Field Confinement and Enhancement in a Plasmonic Picopatch Within a Nanoparticle‐on‐Mirror Resonator

Laser &Photonics Reviews, EarlyView.
A picopatch in a plasmonic nanocavity confines the electromagnetic energy to tiny effective volumes, close to 1nm3, leading to extreme electric field enhancements. Furthermore, a clear signature of strong coupling between the picopatch modes and other modes of the structure is obtained, which strongly modifies the far‐field response. ABSTRACT Plasmonic
Jinna He, Mario Zapata‐Herrera, Xabier Arrieta, Mingli Wan, Yuan Zhang, Javier Aizpurua, Ruben Esteban   +6 more
wiley   +1 more source

Immune Response in PML

, 2001
Progressive multifocal leukoencephalopathy (PML) is a fatal, demyelinating disease caused by JC virus (JCV) in patients with severe immunosuppression.
Petry, Harald, Young, Peter, Kaup, Franz Josef, Weber, Frank, Weber, Thomas, Goldmann, Claudia, Pickhardt, Marcus, Krämer, Marcus, Lüke, Wolfgang   +8 more
core   +1 more source