Results 141 to 150 of about 46,902 (263)

PML Ib primarily localizes to the cytoplasm and influences the localization of nuclear PML isoforms.

, 2013
(A) Immunolocalization of PML Ib. PML +/+ PML −/−, and B1041-1 mouse fibroblast cell lines transfected with a human PML Ib/pcDNA3.1 construct were immunostained with PG-M3 to determine the intracellular localization of PML Ib by confocal (PML+/+) and ...
Pan Zheng (25267), Beth A. McNally (377567), Joanne Trgovcich (184921), Yang Liu (4829), Gerd G. Maul (377568)   +4 more
core   +1 more source

Salvage treatment patterns in multiple myeloma patients progressing after lenalidomide maintenance: A real‐life study from European Myeloma Network (EMN) Italy

British Journal of Haematology, EarlyView.
Summary The extensive use of lenalidomide (Len) in the first‐line treatment of multiple myeloma (MM) has resulted in an increased frequency of patients who have been exposed or are refractory to Len (Len‐R) at first relapse. However, the outcome of Len‐R patients treated at first relapse after autologous haematopoietic stem cell transplantation (AHSCT)
Gregorio Barilà, Angela Grassi, Valeria Ruocco, Carmine Liberatore, Edoardo Olivari, Martina Tinelli, Francesca Fazio, Sonia Morè, Emanuele Favero, Claudio Salvatore Cartia, Nicola Sgherza, Concetta Conticello, Roberto Mina, Martina Gherardini, Giuseppe Mele, Massimo Gentile, Anna Furlan, Massimiliano Arangio Febbo, Maria Livia Del Giudice, Ombretta Annibali, Bernardo Rossini, Edoardo Scomazzon, Marco Talarico, Enrica Antonia Martino, Claudio De Magistris, Francesca Fioritoni, Anna Maria Cafro, Laura Paris, Sara Pezzatti, Roberta Della Pepa, Paola Boggione, Giuseppe Pietrantuono, Valeria Tomarchio, Francesco Vassallo, Maria Luisa Pioltelli, Francesco Pisani, Antonia Cagnetta, Lorenzo De Paoli, Gabriele Buda, Elisabetta Antonioli, Monica Galli, Alberto Tosetto, Pellegrino Musto, Elena Zamagni, Francesca Patriarca, Silvia Mangiacavalli, Renato Zambello, Massimo Offidani, Maria Teresa Petrucci   +48 more
wiley   +1 more source

A Morphological Gradient-based Method to Extract Ocean Front from GOCI Data

, 2014
This study focused on extracting the fronts from ocean color data using the Geostationary Ocean Color Imager (GOCI), the world’s first geostationary ocean color sensor platform.
박영제, 양현, 최종국
core  

Role PML v ribosomálním stresu [PDF]

, 2019
PML je zapojen do řady buněčných procesů. Je organizátorem subjaderných struktur zvaných jaderná tělíska PML a asociuje s jadérkem při odpovědi na ribozomální stres tvorbou jadérkových struktur PML (PNAs).
Kremserová, Petra
core  

Histone deacetylase inhibitors as venetoclax‐sensitising partners in acute myeloid leukaemia: Mechanisms, pharmacology and translational perspectives

British Journal of Pharmacology, EarlyView.
Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley   +1 more source

Feasibility and Safety of Venetoclax for Cytoreduction During Induction Therapy in Newly Diagnosed Acute Promyelocytic Leukemia

European Journal of Haematology, EarlyView.
ABSTRACT Objective This study aimed to evaluate the feasibility and safety of venetoclax as a cytoreductive strategy during induction therapy in newly diagnosed acute promyelocytic leukemia (APL), and to provide an exploratory description of its early efficacy.
Yu Wang, Rong Xiao, Xiaobing Huang, Yi Xiao   +3 more
wiley   +1 more source

Biogeography of Atlantic Salmon in the Cape Breton Highlands, Canada

Fisheries Management and Ecology, EarlyView.
ABSTRACT Atlantic Salmon (Salmo salar) populations have experienced significant declines in recent decades. In Canada, conservation efforts are divided into 16 designatable units (DUs) to address unique regional challenges among genetically distinct populations.
Oscar D. P. Notman‐Grobler, Josh Roland, Ken Oakes, Morgan L. Piczak, Robert J. Lennox   +4 more
wiley   +1 more source

Tracking hatchery and wild Atlantic salmon (Salmo salar) smolt during river exit and early marine migration to assess survival, predation risk and migration speed

Journal of Fish Biology, EarlyView.
Abstract Significant declines in Atlantic salmon (Salmo salar) populations across their range have prompted an increased use of hatchery supplementation programmes to support population recovery. However, concerns persist regarding the effectiveness of these programmes due to limited understanding of how hatchery‐reared salmon perform post‐release in ...
Natalie C. Koopman, David C. Hardie, Robert J. Lennox, Morgan L. Piczak, Frederick G. Whoriskey, Eric B. Brunsdon, Jeffrey A. Hutchings, Glenn T. Crossin   +7 more
wiley   +1 more source

The effect of Changjiang discharge on mid-term variability of chlorophyll-a concentration in the Northeast Asia

, 2014
The Changjiang River, the longest river in Asia, is major a source of nutrient and freshwater for the East China Sea (ECS). Many previous studies reported that the Changjiang Diluted Water (CDW) affects the chlorophyll-a (chl-a) concentration of the ECS ...
박영제, 김광석, 최종국, 문일주   +3 more
core  

Natalizumab-associated PML

, 2017
Progressive multifocal leukoencephalopathy (PML) associated with natalizumab treatment continues to be a severe problem of clinically successful therapy.
Nicholas Schwab, Heinz Wiendl, Gary Cutter, Nico Melzer, Tilman Schneider-Hohendorf   +4 more
core   +1 more source