Results 131 to 140 of about 36,450 (302)
Ubiquitin and ubiquitin‐like modifications in the endoplasmic reticulum stress response
The FEBS Journal, EarlyView.Endoplasmic reticulum (ER) stress activates various proteostasis control processes, including the unfolded protein response, ribosome‐associated quality control, and ER‐associated degradation. Ubiquitin and ubiquitin‐like modifications dynamically regulate these processes to determine cell fate, promoting adaptation or inducing cell death.
Tony Avril +2 more
wiley +1 more source
The FEBS Journal, EarlyView.Insoluble protein aggregates are a hallmark of neurodegenerative diseases like amyotrophic lateral sclerosis (ALS). The ubiquitin–proteasome system (UPS) serves as a neuroprotective quality control mechanism that clears aggregates. PML nuclear bodies (NBs) were proposed to serve as hubs for SUMO‐primed ubiquitylation and degradation of misfolded ...
Tabea Stark, Stefan Müller
wiley +1 more source
Biogeography of Atlantic Salmon in the Cape Breton Highlands, Canada
Fisheries Management and Ecology, EarlyView.ABSTRACT Atlantic Salmon (Salmo salar) populations have experienced significant declines in recent decades. In Canada, conservation efforts are divided into 16 designatable units (DUs) to address unique regional challenges among genetically distinct populations.
Oscar D. P. Notman‐Grobler +4 more
wiley +1 more source
PML Expression Represses IFN-γ-inducible IP-10 Promoter Activity.
, 2015 Hee Ja Kim (342260) +7 more
openalex +2 more sources
Journal of Fish Biology, EarlyView.Abstract Significant declines in Atlantic salmon (Salmo salar) populations across their range have prompted an increased use of hatchery supplementation programmes to support population recovery. However, concerns persist regarding the effectiveness of these programmes due to limited understanding of how hatchery‐reared salmon perform post‐release in ...
Natalie C. Koopman +7 more
wiley +1 more source
Identification of Three Major Sentrinization Sites in PML
, 1998 Tetsu Kamitani +5 more
openalex +1 more source
Treatment Goals for Primary Biliary Cholangitis, an Australian Perspective
Journal of Gastroenterology and Hepatology, EarlyView.ABSTRACT Primary biliary cholangitis (PBC) is an autoimmune liver disease that targets the small intrahepatic bile ducts with diagnosis based on elevated serum alkaline phosphatase (ALP) levels and the presence of anti‐mitochondrial antibodies. Untreated, it may run a progressive course to cirrhosis and hepatic decompensation, at which point liver ...
Simone I. Strasser +6 more
wiley +1 more source