Results 101 to 110 of about 100,358 (268)

The internal crest anatomy of Lambeosaurini (Hadrosauridae: Lambeosaurinae)

The Anatomical Record, EarlyView.
Abstract The supracranial crests of lambeosaurine hadrosaurids have long been a focus of study due primarily to their extreme morphology. The external anatomy of lambeosaurine crests is understood to be highly variable between species, but variation in their internal anatomy is less well understood.
Thomas W. Dudgeon, Courtney Brown, David C. Evans   +2 more
wiley   +1 more source

Pediatric Climbers Experience More Upper Extremity Injuries, Geriatric Climbers More Lower Extremity Injuries, and Increased Shoulder Trauma Associated With Male Individuals in an Emergency Department Analysis of Rock Climbing–Associated Musculoskeletal Injuries

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To analyze epidemiologic trends, injury prevalence, and mechanisms of injury associated with rock climbing. Methods The National Electronic Injury Surveillance System, a public emergency department database, was queried for rock climbing–related injuries from 2014 to 2023. Data extracted included demographics, anatomic region injured, diagnosis,
Titan Z. Alexio, Philip M. Lee, Nathan N. Kim, Keinan B. Agonias, Kyle K. Obana, Andrew J. Luzzi, Jennifer M. Weiss   +6 more
wiley   +1 more source

Post-translational modifications of PML: consequence and implications

Frontiers in Oncology, 2013
The tumor suppressor promyelocytic leukemia protein (PML) predominantly resides in a structurally distinct sub-nuclear domain called PML nuclear bodies (NBs).
Xiwen eCheng, Hung-Ying eKao
doaj   +1 more source

Full-waveform inversion in three-dimensional PML-truncated elastic media

, 2015
We are concerned with high-fidelity subsurface imaging of the soil, which commonly arises in geotechnical site characterization and geophysical explorations.
Fathi, Arash, Kallivokas, Loukas F., Poursartip, Babak   +2 more
core   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Insight into Metabolic 1H-MRS Changes in Natalizumab Induced Progressive Multifocal Leukoencephalopathy Brain Lesions

Frontiers in Neurology, 2017
BackgroundProgressive multifocal leukoencephalopathy (PML) is a severe complication of immunosuppressive therapies, especially of natalizumab in relapsing–remitting multiple sclerosis (MS). Metabolic changes within PML lesions have not yet been described
Ruth Schneider, Barbara Bellenberg, Robert Hoepner, Gisa Ellrichmann, Ralf Gold, Carsten Lukas   +5 more
doaj   +1 more source

Purification, Fluorescent Labeling, and Detyrosination of Mammalian Cell Tubulin for Biochemical Assays

Cytoskeleton, EarlyView.
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas, Yang Yue, Morgan L. Pimm, Takashi Hotta, Ryoma Ohi, Kristen J. Verhey   +5 more
wiley   +1 more source

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

Clinical Pharmacology &Therapeutics, EarlyView.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer, Ellen Cannady, Filip Cuyckens, Ulrike Glaenzel, Camille Granvil, Felix Huth, Alexander D. James, Wenying Li, Céline Veau, Graeme Young, Qin Yue, Gregory S. Walker, Upendra A. Argikar, Jonathan N. Bauman, Cathy Cantalloube, Yu‐Luan Chen, Ping Kang, Patricia Moliner, Mette L. Pedersen, Isabel Piel, Simone Schadt, Hanno Schieferstein, Julia Suchomel, Shuai Wang, S. Cyrus Khojasteh   +24 more
wiley   +1 more source

Revisiting promyelocytic leukemia protein targeting by human cytomegalovirus immediate-early protein 1.

PLoS Pathogens, 2020
Promyelocytic leukemia (PML) bodies are nuclear organelles implicated in intrinsic and innate antiviral defense. The eponymous PML proteins, central to the self-organization of PML bodies, and other restriction factors found in these organelles are ...
Christina Paulus, Thomas Harwardt, Bernadette Walter, Andrea Marxreiter, Marion Zenger, Edith Reuschel, Michael M Nevels   +6 more
doaj   +1 more source

A rapidly converging domain decomposition method for the Helmholtz equation

, 2013
A new domain decomposition method is introduced for the heterogeneous 2-D and 3-D Helmholtz equations. Transmission conditions based on the perfectly matched layer (PML) are derived that avoid artificial reflections and match incoming and outgoing waves ...
Amestoy, Benamou, Berenger, Bollhöfer, Boubendir, Chevalier, Chew, Christiaan C. Stolk, Collino, Davis, Després, Després, Engquist, Engquist, Erlangga, Ernst, Gander, Gander, George, Schädle, Shaidurov, Wang   +21 more
core   +2 more sources