Results 91 to 100 of about 42,451 (299)
Metals, 2015 Al matrix composites reinforced with 40 vol% Fe50.1Co35.1Nb7.7B4.3Si2.8 glassy particles have been produced by powder metallurgy, and their microstructure and mechanical properties have been investigated in detail.
Özge Balcı +7 more
doaj +1 more source
The role of PML proteins in adenovirus type 5 infection and the type I interferon response [PDF]
Promyelocytic leukaemia (PML) proteins consist of a collection of related isoforms that are the nucleating components of sub-nuclear structures termed PML nuclear bodies (PML NBs). Numerous functions are attributed to PML and PML NBs, including a role
Wright, Jordan
core
PML inhibits HCMV gene transcription.
, 2023 PML knockout (PML-KO), PML overexpressing (PML-OE), and their controls (Ctl and NC, respectively) cells were infected with HCMV Towne strain at an MOI of 5 and collected at the indicated times for viral gene transcription quantification.
Fei Hu (191861) +14 more
core +1 more source
NAT10-mediated N4-acetylcytidine modification drives RNA splicing of PML to alleviate adipose-derived stem cell senescence and promote diabetic wound healing. [PDF]
Clin Transl MedN‐acetyltransferase 10 (NAT10) catalyses N4‐acetylcytidine (ac4C) modification of PML pre‐mRNA, shifting splicing from the senescence‐promoting PML‐FL to the senescence‐inhibiting PML‐S isoform via SRSF1. This rejuvenates adipose‐derived stem cells (ADSCs) by reducing senescence markers and senescence‐associated secretory phenotype (SASP), thereby ...
Wei W +9 more
europepmc +2 more sources
The Anatomical Record, EarlyView.Abstract The upper carbonate concretion levels of the Romualdo Formation (Aptian, Brazil) have yielded several theropod dinosaur remains, including spinosaurids and the coelurosaurs Santanaraptor placidus and Mirischia asymmetrica, the phylogenetic affinities of which are controversial.
Rafael Delcourt +4 more
wiley +1 more source
The PML-RAR alpha transcript in long-term follow-up of acute promyelocytic leukemia patients
, 2001 Background and Objectives. Detection of PML-RAR alpha transcripts by RT-PCR is now established as a rapid and sensitive method for diagnosis of acute promyelocytic leukemia (APL), Although the majority of patients in longterm clinical remission are ...
Gameiro, P +11 more
core
The internal crest anatomy of Lambeosaurini (Hadrosauridae: Lambeosaurinae)
The Anatomical Record, EarlyView.Abstract The supracranial crests of lambeosaurine hadrosaurids have long been a focus of study due primarily to their extreme morphology. The external anatomy of lambeosaurine crests is understood to be highly variable between species, but variation in their internal anatomy is less well understood.
Thomas W. Dudgeon +2 more
wiley +1 more source
Post-translational modifications of PML: consequence and implications
Frontiers in Oncology, 2013 The tumor suppressor promyelocytic leukemia protein (PML) predominantly resides in a structurally distinct sub-nuclear domain called PML nuclear bodies (NBs).
Xiwen eCheng, Hung-Ying eKao
doaj +1 more source
, 2010 Promyelocytic leukemia protein (簡稱PML)為一種抑癌蛋白。其會於細胞核中形成特殊的斑點狀構造，稱為PML-nuclear body (PML-NB)。PML-NB參與許多不同細胞生理功能的調控，例如誘發細胞凋亡、抑制細胞生長與促使細胞老化。當細胞受到壓力時，PML蛋白表現量會上升；反之，在人類腫瘤細胞中常出現PML蛋白消失的現象。然而，目前調控PML蛋白穩定性的因子之研究尚未透徹。在這篇論文中我們發現，BTB-Kelch蛋白DIP-2扮演著負調節者的角色 ...
江政達, Chiang, Cheng-Ta
core
Lower Extremity Sprains and Knee/Ankle Injury Predominate Among Pediatric Dancers
Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.Purpose To determine the most common body regions, diagnoses, and mechanisms of injury among pediatric dance‐related injuries in the United States. Methods A descriptive epidemiologic analysis of the National Electronic Injury Surveillance System from January 1, 2019 to December 31, 2023 identified emergency department presentations for primary dance ...
Katherine Koch +6 more
wiley +1 more source