Results 131 to 140 of about 19,899 (215)

Kidney-sparing immunotherapy for lynch syndrome-associated upper tract urothelial carcinoma following colon cancer: a case report. [PDF]

Front Oncol
Xie H, Xie Q, Feng C, Wei K, Zhong F, Wen J, Gao J, Pu X, Ye C.   +8 more
europepmc   +1 more source

Pharmacologic Inhibition of PMS2 Induces MMR Deficiency and Response to Immune Checkpoint Blockade. [PDF]

Cancer Discov
Blagg J, Riou P, Hervieu A, Piumatti E, Rodriguez-Plata MT, Battuello P, Peall A, Amodio V, Vitiello PP, Nightingale DJH, Bago R, Tongue P, Slater T, Parmar K, Patel P, Rodríguez González J, Clark DE, Langley GW, Nichols C, Guarné A, Winship PCM, Baker M, Drysdale M, Germano G, Bardelli A.   +24 more
europepmc   +1 more source

PMS2 Nuclear Expression Intact [PDF]

, 2020
openaire   +1 more source

Heterogeneity in Clinicopathological and PD-L1 Expression Profiles Across Mismatch Repair Protein Deficiency Patterns in Endometrial Carcinoma. [PDF]

Cancers (Basel)
Xiao Y, Yu H, Huang D, Liu S, Wang Y, Ren R, Hu H, Wang S, Yu H, Li Y, Han L.   +10 more
europepmc   +1 more source

Bayesian Integration of Tumor Mutational Signatures and Somatic Features Refines Pathogenicity Assessment of Germline Mismatch Repair Variants. [PDF]

Hum Mutat
Amzaleg Y, McDonnell KJ, Idos GE, Mathai C, Gray SW, Hampel H, Craig DW.   +6 more
europepmc   +1 more source

Deleterious PMS2 Gene Mutation [PDF]

, 2020
openaire   +1 more source

Cancer Risks for PMS2-associated lynch syndrom

, 2018
Lynch syndrome due to pathogenic variants in the DNA mismatch repair genes MLH1, MSH2, and MSH6 is predominantly associated with colorectal and endometrial cancer, although extracolonic cancers have been described within the Lynch tumor spectrum. However, the age-specific cumulative risk (penetrance) of these cancers is still poorly defined for PMS2 ...
Broeke,Sanne W.Ten, Klift,Heleen M.Vander, Tops,Carli M.J., Aretz,Stefan, Bernstein,Inge, Buchanan,Daniel D., Chapelle,Albert Dela, Capella,Gabriel, Clendenning,Mark, Engel,Christoph, Gallinger,Steven, Garcia,Encarna Gomez, Figueiredo,Jane C., Haile,Robert, Hampel,Heather L., Hopper,John L., Hoogerbrugge,Nicoline, Doeberitz,Magnus Von Knebel, Marchand,Loic Le, Letteboer, Tom G.W., Jenkins,Mark A., Lindblom,Annika, Lindor,Noralane M., Mensenkamp,Arjen R., Møller,Pal, Newcomb,Polly A., Van Os,Theo A.M., Pearlman,Rachel, Pineda,Marta, Rahner,Nils, Redeker,Egbert J.W., Olderode-Berends,Maran J.W., Rosty,Christophe, Schackert,Hans K., Scott,Rodney, Senter,Leigha, Spruijt,Liesbeth, Steinke-Lange,Verena, Suerink,Manon, Thibodeau,Stephen, Vos,Yvonne J., Wagner,Anja, Winship,Ingrid, Hes,J. Frederik, Vasen,Hans F.A., Wijnen,Juul T., Nielsen,Maartje, Win,Aung Ko, Global Public Health & Bioethics, Genetica Klinische Genetica, Child Health   +50 more
openaire   +1 more source

Reconciling the effects of PMS2 in different repeat expansion disease models supports a common expansion mechanism. [PDF]

PNAS Nexus
Miller CJ, Jimenez DA, Walker A, Anupindi K, Hayward BE, Lorenzi HA, Usdin K, Zhao X.   +7 more
europepmc   +1 more source

PMS2 Loss of Nuclear Expression [PDF]

, 2020
openaire   +1 more source

Colorectal Carcinoma Metastatic to the Breast Mimicking Inflammatory Breast Cancer With Mismatch Repair Status Discordant From a Prior Endometrial Primary: A Case Report and a Review of the Literature. [PDF]

Cureus
Walters ML, Figueroa Quast A.
europepmc   +1 more source