Results 111 to 120 of about 6,468 (198)

High prevalence of phenotypic pyrazinamide resistance and its association with pncA gene mutations in Mycobacterium tuberculosis isolates from Uganda.

open access: yesPLoS ONE, 2020
INTRODUCTION:Susceptibility testing for pyrazinamide (PZA), a cornerstone anti-TB drug is not commonly done in Uganda because it is expensive and characterized with technical difficulties thus resistance to this drug is less studied.
Resty Naluyange   +5 more
doaj   +1 more source

Consider the midden

open access: yesInscriptions, 2021
Those who read the essay may be reminded of A.R. Ammon's poem, “Garbage” which a correspondant recently called to my attention. The overlap is coincidental; at time of writing, I was ignorant of that work. This essay investigates meanings of an old term:
David Ritchie
doaj  

Роль саногенного мислення в процесі становлення особистості студента (Role of sanohenny thinking in the process of students’ personality development) [PDF]

open access: yes, 2014
У статті розглядається поняття саногенного мислення та його особливості в процесі становлення особистості студента. Крім того, аналізуються чинники, що впливають на становлення людини, досліджується роль саногенного мислення у цьому процесі.
Гільман, А. (A. Hilman)
core  

Evaluation of DNA primase DnaG as a potential target for antibiotics [PDF]

open access: yes, 2014
Mycobacteria contain genes for several DNA-dependent RNA primases, including dnaG, which encodes an essential replication enzyme that has been proposed as a target for antituberculosis compounds.
Aidan Doherty   +47 more
core   +1 more source

Pyrazinamide resistance associated with pncA gene mutation in Mycobacterium tuberculosis in Japan

open access: yesEpidemiology and Infection, 2002
Thirty Japanese clinical isolates of Mycobacterium tuberculosis were analysed by pyrazinamide susceptibility testing and pyrazinamidase assay, as well as polymerase chain reaction for single-strand conformational polymorphism and direct sequencing of the gene encoding pyrazinamidase (pncA).
T, Endoh   +8 more
openaire   +3 more sources

Effects of alimentary-derived bacterial metabolites on energy metabolism in colonic epithelial cells and inflammatory bowel diseases

open access: yesExploration of Medicine
In this review, we present the main luminal fuels that are responsible for energy production in colonocytes, namely the bacterial metabolites short-chain fatty acids and lactate, which are produced from undigestible polysaccharides and proteins, and ...
Mireille Andriamihaja   +1 more
doaj   +1 more source

Identification of the Genes Required for the Culture of Liberibacter crescens, the Closest Cultured Relative of the Liberibacter Plant Pathogens [PDF]

open access: yes, 2016
Here Tn5 random transposon mutagenesis was used to identify the essential elements for culturing Liberibacter crescens BT-1 that can serve as antimicrobial targets for the closely related pathogens of citrus, Candidatus Liberibacter asiaticus (Las) and ...
Austin G. Davis-Richardson   +3 more
core   +3 more sources

Screening mutations in drug-resistant Mycobacterium tuberculosis strains in Yunnan, China

open access: yesJournal of Infection and Public Health, 2017
Drug-resistant tuberculosis (DR-TB), especially multidrug-resistant tuberculosis (MDR-TB), is a serious medical and societal problem in China. The purpose of this study was to evaluate the mutation characteristics of drug-resistant Mycobacterium ...
Daoqun Li   +5 more
doaj   +1 more source

Evaluation of NAD(+)-dependent DNA ligase of mycobacteria as a potential target for antibiotics [PDF]

open access: yes, 2007
Mycobacteria contain genes for several DNA ligases, including ligA, which encodes a NAD+-dependent enzyme that has been postulated to be a target for novel antibacterial compounds.
Bowater, Richard P.   +6 more
core   +2 more sources

Stumbling on Dover Beach

open access: yesInscriptions, 2022
This is the third in a series of essays, linked thoughts about change over time.  In the space of very few years in world historical terms, English beaches and wave-like rolling hills were transformed.
David Ritchie
doaj  

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