Bacterial pore-forming toxins: The (w)hole story? [PDF]
, 2018 .: Pore-forming toxins (PFTs) are the most common class of bacterial protein toxins and constitute important bacterial virulence factors. The mode of action of PFT is starting to be better understood.
Bischofberger, M. +4 more
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Au@Ag SERRS tags coupled to a lateral flow immunoassay for the sensitive detection of pneumolysin [PDF]
, 2017 Establishing a definitive diagnosis of pneumonia using conventional tests is difficult and expensive. Lateral flow immunoassays (LFIAs) are an advantageous point of care (POC) test option, but they have some limitations in terms of detection and ...
Blanco Covián, Lucía +8 more
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Toxicity of pneumolysin and rDNA derived pneumolysin mutants in rats
, 2000 Pneumolysine is het belangrijkste (cyto-) toxine van Streptococcus pneumoniae. Het is toxisch voor celmembranen, activeert het complement-systeem en bepaalt mede de virulentie van pneumococcen. Pneumolysine wordt daarom als kandidaatvaccin gezien. De toxiciteit van pneumolysine zelf beperkt echter de toepasbaarheid.
Dortant PM +7 more
openaire +2 more sources
S47 Pneumolysin promotes neutrophil: platelet aggregation in vitro [PDF]
, 2016 Jan G. Nel +6 more
openalex +1 more source
Preclinical evaluation of a chemically detoxified pneumolysin as pneumococcal vaccine antigen [PDF]
, 2016 Philippe Hermand +6 more
openalex +1 more source
Microvesicles released from pneumolysin-stimulated lung epithelial cells carry mitochondrial cargo and suppress neutrophil oxidative burst [PDF]
, 2021 Eleftheria Letsiou +7 more
openalex +1 more source
Current and emerging evidence for immunomodulatory therapy in community-acquired pneumonia [PDF]
, 2017 Community-acquired pneumonia (CAP) is the most common infectious disease related cause of death worldwide despite the use of effective antimicrobials. Much of the morbidity and mortality seen in CAP patients at high risk of death has been attributed to ...
Jose, RJ, Wood, D
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The mechanism of pneumolysin‐induced cochlear hair cell death in the rat [PDF]
, 2005 Maryline Beurg +6 more
openalex +1 more source
Etiology of community-acquired pneumonia in hospitalized children based on WHO clinical guidelines [PDF]
, 2018 Community-acquired pneumonia (CAP) is a major cause of death in developing countries and of morbidity in developed countries. The objective of the study was to define the causative agents among children hospitalized for CAP defined by WHO guidelines and ...
Bescher-Ninet, Béatrice +8 more
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Identifying an animal model to study the extracellular role of the bacterial toxin listeriolysin O [PDF]
, 2015 Biological and Biomedical SciencesListeriolysin O (LLO) is a cholesterol- dependent cytolysin (CDC) secreted by the foodborne, facultative intracellular pathogen Listeria monocytogenes.
Yan, Shirui
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