Results 111 to 120 of about 6,232 (197)
Advanced Science, Volume 12, Issue 35, September 18, 2025.Macrophage‐derived Galectin‐3 amplifies TGFβ1 signaling to drive diabetic kidney fibrosis: a novel therapeutic target. Abstract Over 30% of patients with type 2 diabetes develop diabetic kidney disease (DKD), which has emerged as a major contributor to end stage renal disease.
Yibing Chen +17 more
wiley +1 more source
Revista CientíficaIschemia–reperfusion injury causes oxidative stress and inflammation, leading to skeletal muscle damage. This study investigates the role of N–acetylcysteine in modulating oxidative stress and inflammatory biomarkers specifically Podocalyxin and ...
Emel Sabaz Karakeci +1 more
doaj +1 more source
The Role of WT1 in Embryonic Development and Normal Organ Homeostasis. [PDF]
, 2016 The Wilms' tumor suppressor gene 1 (Wt1) is critically involved in a number of developmental processes in vertebrates, including cell differentiation, control of the epithelial/mesenchymal phenotype, proliferation, and apoptosis.
Muñoz-Chapuli, Ramon, Wilm, Bettina
core +1 more source
Advanced NanoBiomed Research, Volume 5, Issue 9, September 2025.Kidney stones cause significant pain and healthcare costs. Current prediction, diagnosis, and treatment options are limited. Extracellular vesicles (EVs), rich in proteins, lipids, and nucleic acids, offer a promising solution. This review explores the roles of EVs in kidney stone management, highlighting their potential as biomarkers and therapeutic ...
Wang Zhu +3 more
wiley +1 more source
セイ サイボウ ケイ シュヨウ ニ オケル ポドカリキシン ノ ハツゲン カイセキ [PDF]
, 2009 論文内容要旨学位取得大学:山形大学 ; 報告番号:医博乙第557号 ; 学位の種類: 論文 ; 学位の種別:博士 ...
早津 徳人
core +1 more source
DNA methylation map in circulating leukocytes mirrors subcutaneous adipose tissue methylation pattern: a genome-wide analysis from non-obese and obese patients [PDF]
, 2018 The characterization of the epigenetic changes within the obesity-related adipose tissue will provide new insights to understand this metabolic disorder, but adipose tissue is not easy to sample in population-based studies.
Carreira, M. C. +11 more
core +1 more source
Advanced Materials, Volume 37, Issue 32, August 14, 2025.Surprisingly, a cell can bind to itself to make a self‐adhesion, which engineered here to improve how cells attach to biomaterials. Nanoprinting are used to make 3D structures smaller than cells–called Self‐Adhesion‐Tunnels (SATs)–around which cells can wrap and bind to themselves.
Anamika Singh +4 more
wiley +1 more source
ARHGDIA mutations cause nephrotic syndrome via defective RHO GTPase signaling [PDF]
, 2013 Nephrotic syndrome (NS) is divided into steroid-sensitive (SSNS) and -resistant (SRNS) variants. SRNS causes end-stage kidney disease, which cannot be cured.
Antignac +33 more
core +2 more sources
Cancer Communications, Volume 45, Issue 12, Page 1760-1766, December 2025.
Carine Ngo +30 more
wiley +1 more source
Acta Physiologica, Volume 241, Issue 8, August 2025.ABSTRACT Aim Podocytes, highly specialized epithelial cells located in the glomerulus of the kidney, are essential to the filtration barrier that ensures separation of blood and urine. These cells exhibit a unique architecture, characterized by an intricate network of foot processes interconnected by slit diaphragms, which serve as a critical selective
Desiree Loreth +2 more
wiley +1 more source