Results 81 to 90 of about 3,511 (163)
[A study of urinary podocalyxin in children with IgA nephropathy].
Nihon Jinzo Gakkai shi, 1995 The existence of podocalyxin (PCX) in urine sediments of 30 children with IgA nephropathy was identified by positive findings of immunofluorescence testing using a monoclonal antibody (PHM-5). Three structures (cells (podocytes), casts, granules) were stained and arbitrarily scored according to their numbers and intensity of fluorescence.
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Renal Failure, 2019 Background: This investigation was managed to explore whether miR-193a in combination with two podocytes, namely, Wilms tumor type 1 (WT1) and podocalyxin (PODXL), were feasible in estimating onset and prognosis of idiopathic membranous nephropathy (IMN).
Wei Zhang, Yeping Ren, Jie Li
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Production and characterization of murine monoclonal antibodies against human podocalyxin
Tissue Antigens, 2006 AbstractPodocalyxin (podxl) is a protein with a peptide bone of ∼55.5 kDa that undergoes a post‐translational glycosylation, yielding a final molecular mass from ∼145 to ∼200 kDa. This protein is normally found covering the vascular side of the epithelial glomerular cells, the podocytes, and its presence is essential to maintain a normal renal function.
Rodríguez, Ramón B. +4 more
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Mechanisms by which heme oxygenase rescue renal dysfunction in obesity
Redox Biology, 2014 Obesity and excessive inflammation/oxidative stress are pathophysiological forces associated with kidney dysfunction. Although we recently showed that heme-oxygenase (HO) improves renal functions, the mechanisms are largely unclear. Moreover, the effects
Joseph Fomusi Ndisang, Shuchita Tiwari
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Role of podocalyxin in hematopoiesis and cell migration
, 2008 CD34 and its relatives, Podocalyxin and Endoglycan, comprise of a family of surface sialomucins expressed by hematopoietic stem/progenitor cells, and vascular endothelia. Recent data suggest that they serve as either pro- or anti-adhesion molecules depending on their cellular context and their post-translational modifications.
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Podocalyxin promotes vascular barrier function
, 2019 The CD34-family sialomucin, podocalyxin (Podxl), is broadly expressed on the luminal face of blood vessels in adult mammals; however, its biological function on vascular endothelial cells (vEC) is not well-defined. Here, we reveal specific functions for podocalyxin in maintaining endothelial barriers using HUVEC monolayers as a model in vitro. Detailed
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Dysregulated endometrial podocalyxin and LIF expression in women with ovarian endometrioma
Gynecological EndocrinologyObjective To investigate whether ovarian endometrioma is associated with disruption of the endocrine-regulated transition between the anti-adhesive modulator podocalyxin (PCX) and the adhesive modulator leukemia inhibitory factor (LIF) in the endometrium.
Gökçenur Karakelleoğlu +1 more
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Circulating Podocalyxin, Tumstatin/Col-IVα3 and Chitinase 1: New Culprits in Vitiligo Occurrence
Dermatology Practical & ConceptualIntroductionː The roles of anti-adhesive podocalyxin (PODXL), ant-angiogenetic tumstatin/Col-IVα3 and neuroinflammation and innate immunity modulator Chitinase 1 (CHIT-1) in the etiology of vitiligo have not been studied yet.
Şule Gençoğlu
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