Results 131 to 140 of about 28,951 (302)
Experimental Physiology, EarlyView.Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu +7 more
wiley +1 more source
Podocyte injury underlies the progression of focal segmental glomerulosclerosis in the fa/fa Zucker rat [PDF]
, 2001 Nikolaus Gaßler +7 more
openalex +1 more source
Characterization of novel glomerular proteins : role in physiology and disease [PDF]
, 2014 Glomerular damage accounts for the majority of chronic kidney disease cases, the prevalence of which is dramatically escalating worldwide, mainly due to increase in diabetes and associated nephropathy.
Andersson, Ann-Charlotte
core +1 more source
Human podocyte injury in the early course of hypertensive renal injury
World Journal of Clinical Cases, 2019 Hypertension is prevalent in the general population and is regarded as the second leading cause of renal damage and dysfunction, outnumbered only by diabetes. However, the mechanisms remain unclear.To investigate podocyte injury induced by hypertension in the early course without massive proteinuria or renal dysfunction.The hypertension group comprised
Li Yao +7 more
openaire +3 more sources
The Journal of Physiology, EarlyView.Abstract figure legend Sodium thiosulfate (STS) rescues the pronephros phenotype of pdx1 morphants through compensatory upregulation of nitric oxide (NO) metabolism. Zebrafish larvae injected with a control morpholino show the typical pronephros structure at 48 h post‐fertilization (hpf) with and without STS treatment.
Hannes Ott +6 more
wiley +1 more source
Alternative Pathway Dysregulation and the Conundrum of Complement Activation by IgG4 Immune Complexes in Membranous Nephropathy [PDF]
, 2016 Membranous nephropathy (MN), a major cause of nephrotic syndrome, is a non-inflammatory immune kidney disease mediated by IgG antibodies that form glomerular subepithelial immune complexes.
Dorin-Bogdan Borza
core +2 more sources
Aryl Hydrocarbon Receptor in Health and Disease
MedComm, Volume 6, Issue 11, November 2025.Based on the structure and ligands of AhR, this review introduces the AhR‐related signaling pathways and their roles in health and diseases. Agonists and antagonists of AhR as well as new strategies for treatment using the microbial–AhR axis are summarized. A prospect was made for the future use of AhR as a therapeutic target.
Haonan Li +11 more
wiley +1 more source
Is Podocyte Injury Relevant in Diabetic Nephropathy? [PDF]
, 2003 Michele Dalla Vestra +5 more
openalex +1 more source
Cyclosporine A Protects Podocytes by Regulating Transgelin in Adriamycin-Induced Podocyte Injury
Kidney and Blood Pressure ResearchIntroduction: The calcineurin inhibitor cyclosporine A (CsA) has been shown to effectively reduce proteinuria. However, its precise mechanism is still not fully understood. Our previous study showed that CsA reduced proteinuria by directly stabilizing the foot process (FP) cytoskeletal structure via cofilin-1, suggesting that synaptopodin, a podocyte ...
Xiaoyan Li +4 more
openaire +3 more sources
Veterinary Medicine and Science, Volume 11, Issue 6, November 2025.Vasculature‐Associated Lymphoid Tissue (VALT) is a significant tertiary lymphoid tissue that contributes to kidney inflammation and has not yet been identified in ruminants. Our study revealed that VALT in goats consists of typical immune cells, including macrophages, T cells, B cells and high endothelial venules.
Md. Abdul Masum +2 more
wiley +1 more source