Results 141 to 150 of about 29,045 (218)

Mechanisms of hesperetin in alleviating diabetic nephropathy: Network pharmacology, molecular docking, and experimental validation

Journal of Diabetes Investigation, Volume 17, Issue 4, Page 576-587, April 2026.
Hesperetin increases cell viability and reduces cell apoptosis, ferroptosis, release of inflammatory cytokines, and oxidative stress of human kidney tubular cells via repressing IGF1R expression. ABSTRACT Background Diabetic nephropathy (DN) accounts for approximately 50% of chronic kidney disease cases.
Yiwen Guo, Fengjiao Zhang, Yu Jin, Menglu Zhu, Zhiqiang Kang   +4 more
wiley   +1 more source

The urinary albumin‐to‐creatinine ratio can direct personalized prevention and treatment for cardiovascular and chronic kidney disease

Journal of Internal Medicine, Volume 299, Issue 4, Page 444-466, April 2026.
Abstract Increased urinary albumin excretion is a strong predictor for cardiovascular events in persons with and without decreased glomerular filtration rate and can be assessed with the urinary albumin‐to‐creatinine ratio (UACR), which is a selective, sensitive, and convenient method for patients.
Holly J. Kramer, George L. Bakris
wiley   +1 more source

Cellular microenvironment of erythropoietin‐producing cells in hypoxic and injured mouse kidneys

Experimental Physiology, Volume 111, Issue 4, Page 2236-2267, 1 April 2026.
Abstract The main sources of circulating erythropoietin (Epo) in the adult are kidney Norn cells, a recently identified interstitial cell type capable of becoming renal Epo‐producing (REP) cells following a local decrease in tissue oxygenation. REP cells are restricted to small clusters in the corticomedullary border region, suggesting that their ...
Olga M. Lempke, Thomas Knöpfel, Stellor Nlandu Khodo, Roland H. Wenger   +3 more
wiley   +1 more source

From Single‐Cell Clusters to Causality: ITCH Engagement for CKD Uncovered by Integrative Analysis of MR and MAGMA

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
This graphical abstract illustrates an integrative analysis of single‐cell RNA‐seq data in CKD. DEGs were subsequently identified as candidate genes via Mendelian randomization analysis and combined with MAGMA analysis, ITCH was identified as a key gene.
Xia Zhang, Dongdong Zhang, Jiazhen Shang, Zhitao Zeng, Shouyu Chai, Xincong Lv, Zhimei Lv, Rong Wang   +7 more
wiley   +1 more source

Immune podocyte injury in autoimmune glomerular diseases. [PDF]

Front Immunol
Zhu H, Sun J, Yan Y, Liu P, Huang Y.
europepmc   +1 more source

Integrating Tissue Proteomics and Urinary Analyses to Capture Dynamic Podocyte Injury. [PDF]

Kidney Int Rep
Kajana X, Caridi G, Angeletti A.
europepmc   +1 more source

A vital role for Angptl3 in the PAN-induced podocyte loss by affecting detachment and apoptosis in vitro [PDF]

, 2015
Haimei Liu, Hong Xu, Jia Rao, Rufeng Dai, Xiaoyan Fang, Xiliang Zha, Yi Lin, Yihui Zhai   +7 more
core   +1 more source

Discovery of kidney disease targets using multimodal human podocyte injury models. [PDF]

Stem Cell Reports
Barreto AD, Jiang B, Burt MA, Dimitrakakis N, Musah S.   +4 more
europepmc   +1 more source

Endothelial cell-released CD93 contributes to podocyte injury in idiopathic nephrotic syndrome. [PDF]

Sci Transl Med
Bauer C, Piani F, Troost J, Da Sacco S, Rojas-Sanchez G, Davizon-Castillo P, Davizon-Castillo P, Perin L, Daehn I, Islam MI, Fetsko A, Carrera-Muñoz C, Rovin B, Zhang XL, Banks M, de Lucas-Collantes C, Ordóñez-Álvarez FA, Aparicio-López C, Lanaspa MA, Andres-Hernando A, Segarra A, Martinez C, Bjornstad P, Lucia MS, Schaefer F, Yilmaz A, Zurowska A, Wang X, McCown PJ, Eddy S, Hartman J, Mariani L, Kretzler M, Zhu Y, Bouts AHM, Levtchenko EN, Dougherty JA, Smoyer WE, Kerlin BA, Kallash M, Soranno DE, Cabrera-Sevilla JE, Gonzalez-Rodriguez JD, Siegele BJ, Tsuji S, Kaneko K, Sethna CB, Srivastava T, Bitzer M, O'Connor CL, Dimberg A, Zhao S, Yu L, Thurman JM, Johnson RJ, Cara-Fuentes G.   +55 more
europepmc   +1 more source

Editorial: Podocyte Pathology and Nephropathy [PDF]

, 2015
Barbara Lewko, Gavin Iain Welsh, Maciej Jankowski   +2 more
core   +1 more source