Results 171 to 180 of about 28,951 (302)
Food Science &Nutrition, Volume 13, Issue 10, October 2025.This review shows evidence from preclinical and clinical studies, supporting the therapeutic potential of polyphenols for diabetic kidney disease (DKD). This is due to their diverse bioactive properties and ability to intervene in intricate mechanisms of the disease.
Esienanwan E. Efiong +10 more
wiley +1 more source
Journal of Extracellular Biology, Volume 4, Issue 10, October 2025.Abstract Diabetic kidney disease (DKD) is a health burden that lacks specific and early diagnostic biomarkers. For their discovery, we sequenced urinary extracellular vesicle miRNAs in a type 1 diabetes cohort of males with and without DKD. The results were replicated by sequencing or qPCR in two independent cohorts and six published datasets ...
Karina Barreiro +14 more
wiley +1 more source
MedComm, Volume 6, Issue 10, October 2025.This review comprehensively examines the regulatory mechanisms and physiological roles of guanine nucleotide exchange factors (GEFs) and their small GTPase substrates, highlighting their significance in cellular processes and disease pathogenesis.
Zexing Lin +15 more
wiley +1 more source
Activation of Gαq-Coupled Signaling Pathways in Glomerular Podocytes Promotes Renal Injury
, 2005 Liming Wang +7 more
openalex +1 more source
Perirenal Fat in Disease Progression: From Inflammatory Mediator to Therapeutic Target
International Journal of Urology, Volume 32, Issue 10, Page 1314-1320, October 2025.ABSTRACT Perirenal fat (PRF), the adipose tissue that encases the kidneys, has long been considered a passive energy reservoir and mechanical buffer. However, emerging evidence has identified PRF as a biologically active visceral fat depot that secretes adipocytokines, inflammatory mediators, and other bioactive molecules, and thereby contributes to ...
Eiji Kashiwagi
wiley +1 more source
Low‐protein diet for chronic kidney disease: Evidence, controversies, and practical guidelines
Journal of Internal Medicine, Volume 298, Issue 4, Page 319-335, October 2025.Abstract The benefits of a low‐protein diet (LPD) in patients with altered kidney function remain controversial. Dietary intake studies are inherently complex and may present numerous biases that must be understood and controlled. Due to these challenges, the scientific evidence in this area remains limited and is subject to dispute.
Denise Mafra +4 more
wiley +1 more source
Nephrology, Volume 30, Issue 10, October 2025.The study investigated the association between darbepoetin alfa (DA) dosage and urinary protein levels in real‐world chronic kidney disease (CKD) patients. High‐dose DA administration was associated with reduced proteinuria, particularly in diabetic kidney disease (DKD) patients with high erythropoiesis resistance index (ERI‐1B) values, suggesting ...
Shuma Hirashio +3 more
wiley +1 more source
Overexpression of Cyclooxygenase-2 Predisposes to Podocyte Injury
, 2007 Huifang Cheng +9 more
openalex +1 more source