Podocyte injury - Open Access .click

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Podocyte OTUD5 alleviates diabetic kidney disease through deubiquitinating TAK1 and reducing podocyte inflammation and injury

Nature Communications
Recent studies have shown the crucial role of podocyte injury in the development of diabetic kidney disease (DKD). Deubiquitinating modification of proteins is widely involved in the occurrence and development of diseases.
Ying Zhao +11 more
doaj +1 more source

Hypertension and age‐related focal global glomerulosclerosis are associated with biomarkers for cellular senescence

Physiological Reports, Volume 14, Issue 3, February 2026.
Abstract Arterionephrosclerosis is characterized by focal global glomerulosclerosis (FGGS), which is a constant feature of aging and hypertension. FGGS begins as normal‐appearing glomeruli that undergo tuft contraction (TC) and progress to global glomerulosclerosis (GGS).
Michael D. Hughson +4 more
wiley +1 more source

Role of Podocyte in Kidney Disease

Frontiers in Bioscience-Landmark
Podocytes are epithelial cells lining the outer surface of the renal glomerular capillaries and they play a pivotal role in maintaining the structural and functional integrity of the glomerular filtration barrier.
Sufia Husain
doaj +1 more source

Nicotine instigates podocyte injury via NLRP3 inflammasomes activation [PDF]