Results 61 to 70 of about 44,214 (194)

Calcium/Calmodulin Kinase IV Controls the Function of Both T Cells and Kidney Resident Cells

Frontiers in Immunology, 2018
Calcium calmodulin kinase IV (CaMK4) regulates multiple processes that significantly contribute to the lupus-related pathology by controlling the production of IL-2 and IL-17 by T cells, the proliferation of mesangial cells, and the function and ...
Andrew P. Ferretti, Rhea Bhargava, Shani Dahan, Maria G. Tsokos, George C. Tsokos   +4 more
doaj   +1 more source

Glomerular endothelial derived vesicles mediate podocyte dysfunction: A potential role for miRNA.

PLoS ONE, 2020
MicroRNAs (miRNA) are shown to be involved in the progression of several types of kidney diseases. Podocytes maintain the integrity of the glomerular basement membrane.
N Hill, D L Michell, M Ramirez-Solano, Q Sheng, C Pusey, K C Vickers, K J Woollard   +6 more
doaj   +1 more source

Cultured human podocytes endocytose albumin.

, 2013
A, Confocal image of cultured human podocytes placed at 4°C (inhibits endocytosis) or 37°C (promotes endocytosis) and treated with 1.5 mg/ml human FITC-albumin. Bright green vesicles seen in the podocytes at 37°C are FITC-albumin containing endosomes. B,
Judith Blaine (277407), Moshe Levi (277405), Patrick Dummer (277402), Jeffrey Kopp (277403), Liru Qiu (277404), Kayo Okamura (277401), Sarah Faubel (277406)   +6 more
core   +1 more source

MicroRNA-770-5p contributes to podocyte injury via targeting E2F3 in diabetic nephropathy [PDF]

Brazilian Journal of Medical and Biological Research
Diabetic nephropathy (DN) has been identified as the major cause of end-stage renal disease (ESRD) in most developed countries. MicroRNA-770-5p depletion could repress high glucose (HG)-triggered apoptosis in podocytes, and downregulation of E2F ...
Juanjuan Guo, Jie Han, Jieying Liu, Shaoli Wang   +3 more
doaj   +2 more sources

Characterization of FcRn knockout podocytes.

, 2019
A, Conditionally immortalized wild type (WT) and FcRn knockout (KO) podocytes express the podocyte markers podocin and Wilms Tumor 1 (WT1). Scale bar 20 μm. B, FcRn KO podocytes have minimal expression of FcRn mRNA.
Linda Lewis (6407513), Judith Blaine (277407), Pantipa Tonsawan (6407516), Parmjit S. Jat (634721), Makoto Miyazaki (316683), Evgenia Dobrinskikh (252465), James Dylewski (6407510)   +6 more
core   +1 more source

Expression of uPAR in Urinary Podocytes of Patients with Fabry Disease

International Journal of Nephrology, 2017
Background. Despite enzyme replacement therapy, Fabry nephropathy still progresses. Podocyturia is an irreversible event that antedates proteinuria and leads to chronic renal failure.
Hernán Trimarchi, Romina Canzonieri, Amalia Schiel, Juan Politei, Cristian Costales-Collaguazo, Aníbal Stern, Matías Paulero, Tatiana Rengel, Lara Valiño-Rivas, Mariano Forrester, Fernando Lombi, Vanesa Pomeranz, Romina Iriarte, Alexis Muryan, Alberto Ortiz, María Dolores Sanchez-Niño, Elsa Zotta   +16 more
doaj   +1 more source

Images of Urinary Podocytes.

, 2014
A) Representative immunofluorescent images of urinary podocytes in high risk patients with PE stained with podocin (pod), synaptopodin (syn) and colocalized (merged).
Robert M. Moore (596001), Kwanghee Kim (596000), Hillel W. Cohen (232205), Shuchita Sharma (596002), Andi Qipo (165108), Belinda Jim (322598), Swati Mehta (595999), John C. He (345967)   +7 more
core   +1 more source

The integrin repertoire drives YAP-dependent epithelial:stromal interactions during injury of the kidney glomerulus

Nature Communications
The kidney glomerulus is a filtration barrier in which capillary loop architecture depends on epithelial-stromal interactions between podocytes and mesangial cells.
Evelyne Huynh-Cong, Victoria Driscoll, Sandrine Ettou, Keith Keller, Amha Atakilit, Mary E. Taglienti, Saurabh Kumar, Astrid Weins, Valerie A. Schumacher, Jordan A. Kreidberg   +9 more
doaj   +1 more source

Columbianetin protects from high-glycemic podocyte damage by regulating autophagy

Linchuang shenzangbing zazhi, 2021
Objective To explore the protective effect of columbianetin（CBT）on the injury of podocytes induced by high glucose and its mechanism.Methods Immortalized murine foot cell line MPC-5 was cultured in vitro and the effects of CBT on injury and autophagy ...
Shi Lang, Song Zhi-xia, Zhang Ya-fei
doaj  

Systematic analysis of a novel human renal glomerulus-enriched gene expression dataset [PDF]

, 2010
Glomerular diseases account for the majority of cases with chronic renal failure. Several genes have been identified with key relevance for glomerular function.
Clemens D Cohen, Ilka Edenhofer, Felix Eichinger, Rastaldi, Maria P., Maja T. Lindenmeyer, Hans-Joachim Anders, Lindenmeyer, M T, Cohen Clemens D., Eichinger, Felix, Eichinger Felix, Kretzler, Matthias, Mattinzoli, D, Deborah Mattinzoli, Maja T Lindenmeyer, Maria P. Rastaldi, Cohen, Clemens D., Kretzler, M, Sen, Kontheari, Rastaldi Maria P., Matthias Kretzler, Edenhofer, I, Lindenmeyer, Maja T., Anders Hans-Joachim, Clemens D. Cohen, Cohen, C D, Maria P Rastaldi, Mattinzoli Deborah, Mattinzoli, Deborah, Anders, Hans-Joachim, Sen Kontheari, Kretzler Matthias, Edenhofer, Ilka, Kontheari Sen, Lindenmeyer Maja T., Rastaldi, M P, Edenhofer Ilka, Eichinger, F, Sen, K   +37 more
core   +1 more source