Results 11 to 20 of about 6,904 (161)

A Pseudovirus-Based Method for the Simultaneous Quantitation of Neutralization Antibodies Against All Three Poliovirus Serotypes. [PDF]

MedComm (2020)
By optimizing P1 expression, sensitive cell selection, and plasmid transfection ratios, we produced a high‐titer poliovirus pseudovirus. Based on high‐titer pseudovirus encoding distinct fluorophores (E2, eGFP, and RFP), we developed a tri‐color pseudovirus‐based neutralization assay (PBNA) for the simultaneous quantification of neutralizing antibodies
Liu M, Yu Y, Li Y, Tao Z, Huang L, Wu X, Zhang Y, Zhu S, Sun Q, Ji T, Wang D, Liang Z, Liu S, Cai M, An Y, Li J, Huang W, Liao G, Yi L, Ma L, Zhang L, Wang Y.   +21 more
europepmc   +2 more sources

Promising opportunities to improve polio vaccines

Биопрепараты: Профилактика, диагностика, лечение, 2022
Polioviruses belong to Enterovirus C species and cause severe lesions of the nervous system. In the post-polio eradication era, the World Health Organisation recommends inactivated polio vaccines for effective long-term protection of the population.
E. E. Evreinova, L. M. Khantimirova, V. A. Shevtsov, V. A. Merkulov, V. P. Bondarev   +4 more
doaj   +1 more source

Effect of Inactivated Poliovirus Vaccine Campaigns, Pakistan, 2014–2017

Emerging Infectious Diseases, 2018
Pakistan began using inactivated poliovirus vaccine alongside oral vaccine in mass campaigns to accelerate eradication of wild-type poliovirus in 2014.
Nicholas C. Grassly, Mufti Zubair Wadood, Rana M. Safdar, Abdirahman Sheikh Mahamud, Roland W. Sutter   +4 more
doaj   +1 more source

Microneedle patch as a new platform to effectively deliver inactivated polio vaccine and inactivated rotavirus vaccine

npj Vaccines, 2022
We recently reported a lack of interference between inactivated rotavirus vaccine (IRV) and inactivated poliovirus vaccine (IPV) and their potential dose sparing when the two vaccines were administered intramuscularly either in combination or standalone ...
Sung-Sil Moon, Marly Richter-Roche, Theresa K. Resch, Yuhuan Wang, Kimberly R. Foytich, Houping Wang, Bernardo A. Mainou, Winston Pewin, Jeongwoo Lee, Sebastien Henry, Devin V. McAllister, Baoming Jiang   +11 more
doaj   +1 more source

Reduced mucosal immunity to poliovirus after cessation of trivalent oral polio vaccine

Human Vaccines & Immunotherapeutics, 2021
The switch from using only trivalent oral polio vaccine (tOPV) to sequential schedules combining inactivated poliovirus vaccine (IPV) and bivalent oral polio vaccine (bOPV) for polio vaccination will cause changes to mucosal immunity against polio in ...
Ting Zhao, Jing Li, Hongyuan Shi, Hui Ye, Rufei Ma, Yuting Fu, Xiaochang Liu, Guoliang Li, Xiaolei Yang, Zhimei Zhao, Jingsi Yang   +10 more
doaj   +1 more source

Development of Thermostable Lyophilized Sabin Inactivated Poliovirus Vaccine

mBio, 2018
As oral poliovirus vaccine (OPV) causes vaccine-associated paralytic poliomyelitis, the polio endgame strategy introduced by the Global Polio Eradication Initiative calls for a phased withdrawal of OPV and an introduction of inactivated poliovirus ...
Woo-Jin Shin, Daiki Hara, Francisca Gbormittah, Hana Chang, Byeong S. Chang, Jae U. Jung   +5 more
doaj   +1 more source

Impact of polio vaccines (oral polio vaccine - OPV or inactivated polio vaccine - IPV) on rotavirus vaccine-associated intussusception

Human Vaccines & Immunotherapeutics, 2022
Although safe, rotavirus vaccines have been associated with increased intussusception risk. In Brazil, after the oral human rotavirus vaccine (OHRV) introduction in the childhood immunization, in 2006, increased intussusception risk was identified after ...
Camila Cristina Martini Rodrigues, Eder Gatti Fernandes, Paulo Piva dos Santos, Renato Yoshio Eguti, Antonio Carlos Pedroso-de-Lima, Gisela Tunes da Silva, Ana Marli Christovam Sartori   +6 more
doaj   +1 more source

Relationship Between Helicobacter pylori IgG Seroprevalence and the Immune Response to Poliovirus Vaccine Among School-Age Children From a Population With Near-Universal Immunity Level

Frontiers in Medicine, 2022
ObjectivesTo examine the association between Helicobacter pylori seroprevalence and serum pepsinogens (PGs) as markers of gastric inflammation), with high neutralizing antibody titers to poliovirus type 1 and 3 vaccine strains among children age 3–4 ...
Layaly Badran Abu Zher, Merav Weil, Eias Kassem, Nael Elias, Myron M. Levine, Khitam Muhsen   +5 more
doaj   +1 more source

Estimated Effect of Inactivated Poliovirus Vaccine Campaigns, Nigeria and Pakistan, January 2014–April 2016

Emerging Infectious Diseases, 2017
In 2014, inactivated poliovirus vaccine (IPV) campaigns were implemented in Nigeria and Pakistan after clinical trials showed that IPV boosts intestinal immunity in children previously given oral poliovirus vaccine (OPV). We estimated the effect of these
George Shirreff, Mufti Zubair Wadood, Rui Gama Vaz, Roland W. Sutter, Nicholas C. Grassly   +4 more
doaj   +1 more source

Does IPV Boost Intestinal Immunity among Children under Five Years of Age? An Experience from Pakistan

Vaccines, 2023
The oral poliovirus vaccine (OPV) has been the mainstay of polio eradication, especially in low-income countries, and its use has eliminated wild poliovirus type 2.
Muhammad Atif Habib, Sajid Bashir Soofi, Imtiaz Hussain, Imran Ahmed, Zamir Hussain, Rehman Tahir, Saeed Anwar, Simon Cousens, Zulfiqar A. Bhutta   +8 more
doaj   +1 more source