Results 41 to 50 of about 6,904 (161)

Systematic Review of Postvaccination Ocular Adverse Events: A Comprehensive Analysis of Published Reports

open access: yesJournal of Medical Virology, Volume 97, Issue 12, December 2025.
ABSTRACT Ocular adverse events following COVID‐19 vaccination are well described; however, systematic analyses of non‐COVID antiviral vaccines remain limited. This review aimed to evaluate ocular complications associated with non‐COVID antiviral immunizations, including influenza, varicella‐zoster (VZV), human papillomavirus (HPV), and hepatitis B (HBV)
Yaru Zou   +5 more
wiley   +1 more source

Experimental Approaches to the Development of Inactivated Poliovirus Vaccine Based on Sabin Strains

open access: yesЭпидемиология и вакцинопрофилактика, 2016
The results of development of experimental series of inactivated poliovirus vaccine based on Sabin strains (s-IPV) using conventional modern techniques are presented.
A. P. Ivanov   +5 more
doaj   +1 more source

Fractional-dose inactivated poliovirus vaccine, India

open access: yesBulletin of the World Health Organization, 2019
In 2016, the World Health Organization (WHO) announced a global shortage of inactivated poliovirus vaccine that was expected to last until 2020 at least. In response, WHO's Strategic Advisory Group of Experts on Immunization recommended that countries consider a strategic shift to fractional-dose inactivated poliovirus vaccine, which involves a new ...
Haldar, Pradeep   +7 more
openaire   +2 more sources

Viral Aetiology of Acute Flaccid Paralysis Surveillance Cases, before and after Vaccine Policy Change from Oral Polio Vaccine to Inactivated Polio Vaccine

open access: yesJournal of Tropical Medicine, 2014
Since 1992, surveillance for acute flaccid paralysis (AFP) cases was introduced in Malaysia along with the establishment of the National Poliovirus Laboratory at the Institute for Medical Research.
T. S. Saraswathy Subramaniam   +4 more
doaj   +1 more source

Crosstalk Between Cancer‐Associated Fibroblasts and Immune Cells: Mechanisms and Therapeutic Implications

open access: yesMedComm – Oncology, Volume 4, Issue 4, December 2025.
Cancer‐associated fibroblasts (CAFs) are widely engaged in tumor progression in the tumor microenvironment. CAFs interact actively with immunocytes including tumor‐associated macrophages, T cells, neutrophils, and NK cells in a positive‐feedback loop to sculpt tumor immune microenvironment and participate in tumor activities and antitumor therapy ...
Ya Li   +7 more
wiley   +1 more source

Environmental Surveillance of Polioviruses in Armenia, Colombia before Trivalent Oral Polio Vaccine Cessation

open access: yesViruses, 2019
Although acute flaccid paralysis (AFP) surveillance is the “gold standard” for detecting cases of polio, environmental surveillance can provide supplementary information in the absence of paralytic poliomyelitis cases.
María Mercedes González   +7 more
doaj   +1 more source

The microbiome in cancer

open access: yesiMeta, Volume 4, Issue 5, October 2025.
This comprehensive review elucidates the transformative role of the human microbiome in cancer biology, revealing innovative mechanistic insights into the intricate tumor–microbe interactions across diverse organ systems. This work highlights the clinical and translational value of novel microbiome‐based biomarkers for early detection, prognosis, and ...
Anqi Lin   +50 more
wiley   +1 more source

Promising Prodiginins Biological Activities

open access: yesChemistry &Biodiversity, Volume 22, Issue 9, September 2025.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto   +6 more
wiley   +1 more source

Natural Killer Cell‐Mediated Antitumor Immunity: Molecular Mechanisms and Clinical Applications

open access: yesMedComm, Volume 6, Issue 9, September 2025.
NK cells eliminate tumors via cytotoxicity and cytokine secretion. Tumor microenvironment‐driven immunosuppression and metabolic reprogramming subvert NK cells’ cytotoxicity. The current clinical strategies to restore NK activity include ex vivo expansion for adoptive transfer, CAR‐NK engineering, TME‐remodeling agents, immune checkpoint blockade ...
Nanzhi Luo   +12 more
wiley   +1 more source

Targeting Immune Checkpoints: Basic Signaling Pathways and Clinical Translation in Cancer Therapeutics

open access: yesMedComm – Oncology, Volume 4, Issue 3, September 2025.
Immune checkpoints in tumor immunotherapy. Ligand binding to the receptor inhibits immune cell function, promotes tumor cell immune escape, and suppresses the immune response. The pathways of action are VISTA‐IGSF11, TIM‐3‐Ceacam1, CD47‐SIRPα, CTLA‐4‐CD80/CD86, PD‐L1‐PD‐1, MHC‐1‐LILRB, and CD24 ‐ Siglec ‐10. There are also other immune checkpoints such
Han Sun   +10 more
wiley   +1 more source

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