Frontiers in Microbiology, 2018 The duck hepatitis A virus type 1 (DHAV-1) is a member of Picornaviridae family, the genome of the virus contains a 5′ untranslated region (5′ UTR), a large open reading frame that encodes a polyprotein precursor and a 3′ UTR followed by a poly(A) tail ...
Jun-Hao Chen +18 more
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Poly A- transcripts expressed in HeLa cells. [PDF]
PLoS ONE, 2008 Transcripts expressed in eukaryotes are classified as poly A+ transcripts or poly A- transcripts based on the presence or absence of the 3' poly A tail.
Qingfa Wu +9 more
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Poly(A)-tail profiling reveals an embryonic switch in translational control [PDF]
, 2013 Poly(A) tails enhance the stability and translation of most eukaryotic messenger RNAs, but difficulties in globally measuring poly(A)-tail lengths have impeded greater understanding of poly(A)-tail function. Here we describe poly(A)-tail length profiling
Bartel, David +4 more
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Saltatory Forward Movement of a Poly(A) Polymerase during Poly(A) Tail Addition [PDF]
Journal of Biological Chemistry, 2007 Vaccinia poly(A) polymerase (VP55) interacts with > or = 33-nucleotide (nt) primers via uridylates at two sites (-27/-26 and -10). It adds approximately 30-nt poly(A) tails with a rapid, processive burst in which the first few nt are added without substantial primer movement, and addition of the remaining adenylates is dependent upon a six-uridylate ...
Janice M, Yoshizawa +2 more
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RNA-binding protein CPEB1 remodels host and viral RNA landscapes. [PDF]
, 2016 Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in
Aigner, Stefan +17 more
core +2 more sources
Wide energy-window view on the density of states and hole mobility of poly(p-phenylene vinylene) [PDF]
, 2004 Using an electrochemically gated transistor, we achieved controlled and reversible doping of poly(p-phenylene vinylene) in a large concentration range.
Brom, H. B. +5 more
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The influence of microRNAs and poly(A) tail length on endogenous mRNA–protein complexes
Genome Biology, 2017 Background All mRNAs are bound in vivo by proteins to form mRNA–protein complexes (mRNPs), but changes in the composition of mRNPs during posttranscriptional regulation remain largely unexplored. Here, we have analyzed, on a transcriptome-wide scale, how
Olivia S. Rissland +9 more
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Chain-end modifications and sequence arrangements of antimicrobial peptoids for mediating activity and nano-assembly [PDF]
, 2020 Poly(N-substituted glycine) “peptoids” are an interesting class of peptidomimics that can resist proteolysis and mimic naturally found antimicrobial peptides (AMPs), which exhibit wide spectrum activity against bacteria.
Castelletto, Valeria +9 more
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TED-Seq Identifies the Dynamics of Poly(A) Length during ER Stress
Cell Reports, 2018 Summary: Post-transcriptional RNA processing is a core mechanism of gene expression control in cell stress response. The poly(A) tail influences mRNA translation and stability, but it is unclear whether there are global roles of poly(A)-tail lengths in ...
Yu Mi Woo +6 more
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Control of translation and miRNA-dependent repression by a novel poly(A) binding protein, hnRNP-Q. [PDF]
PLoS Biology, 2013 Translation control often operates via remodeling of messenger ribonucleoprotein particles. The poly(A) binding protein (PABP) simultaneously interacts with the 3' poly(A) tail of the mRNA and the eukaryotic translation initiation factor 4G (eIF4G) to ...
Yuri V Svitkin +8 more
doaj +1 more source