Results 51 to 60 of about 114,953,758 (241)

mRNA poly(A) tail, a 3' enhancer of translational initiation

open access: yes, 2008
To evaluate the hypothesis that the 3' poly(A) tract of mRNA plays a role in translational initiation, we constructed derivatives of pSP65 which direct the in vitro synthesis of mRNAs with different poly(A) tail lengths and compared, in reticulocyte ...
Munroe, David, Jacobson, Allan
core   +1 more source

An Explicit Constitutive Reconstruction Framework for Mechanical Characterization of Miniaturized 3D‐Printed Specimens

open access: yesAdvanced Engineering Materials, EarlyView.
An explicit constitutive reconstruction framework enables accurate tensile characterization of miniaturized additively manufactured specimens using only the grip‐to‐grip displacement measurements. Progressive validation through self‐consistency, analytical comparison, and inverse finite element method (iFEM) benchmarking demonstrates constitutive ...
Junqing Leng   +4 more
wiley   +1 more source

DPAC: A Tool for Differential Poly(A)–Cluster Usage from Poly(A)–Targeted RNAseq Data

open access: yesG3: Genes, Genomes, Genetics, 2019
Poly(A)-tail targeted RNAseq approaches, such as 3′READS, PAS-Seq and Poly(A)-ClickSeq, are becoming popular alternatives to random-primed RNAseq to focus sequencing reads just to the 3′ ends of polyadenylated RNAs to identify poly(A)-sites and ...
Andrew Routh
doaj   +1 more source

Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice

open access: yesNature Communications, 2023
In mammals, the production of mature oocytes necessitates rigorous regulation of the discontinuous meiotic cell-cycle progression at both the transcriptional and post-transcriptional levels. However, the factors underlying this sophisticated but explicit
Xue Jiang   +14 more
doaj   +1 more source

From Food to Power: Hydrogel Thermoelectrics for Ingestible Electronics

open access: yesAdvanced Functional Materials, EarlyView.
We introduce a fully edible thermoelectric–electrochromic platform that harvests heat from food and converts it into a visible color change. N‐type and p‐type hydrogel thermoelectric generators connected in series power anthocyanin‐based electrochromic displays, demonstrating the feasibility of safe, biodegradable, ingestible systems for on‐food ...
Antonia Georgopoulou   +3 more
wiley   +1 more source

Impact of poly(A)-tail G-content on Arabidopsis PAB binding and their role in enhancing translational efficiency

open access: yesGenome Biology, 2019
Background Polyadenylation plays a key role in producing mature mRNAs in eukaryotes. It is widely believed that the poly(A)-binding proteins (PABs) uniformly bind to poly(A)-tailed mRNAs, regulating their stability and translational efficiency.
Taolan Zhao   +11 more
doaj   +1 more source

Wearable Smart Patches on Sustainable Chitosan With Reversible Microbial Growth‐Inhibitory Properties

open access: yesAdvanced Functional Materials, EarlyView.
ABSTRACT Chitosan, a polysaccharide upcycled from biowaste, has long promised sustainable, biocompatible, and antimicrobial films and devices, an appeal reinforced by its recent regulatory recognition, with several chitosan‐based antibacterial dressings gaining clearance through the Food and Drug Administration's 510(k) pathway.
Jacopo Nicoletti   +16 more
wiley   +1 more source

TAIL-seq: Genome-wide determination of poly(A) tail length and 3' end modifications

open access: yes, 2018
Global investigation of the 30 extremity of mRNA (30-terminome), despite its importance in gene regulation,has not been feasible due to technical challenges associated with homopolymeric sequences and relative paucity of mRNA.
Minju Ha   +3 more
core   +2 more sources

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han   +5 more
wiley   +1 more source

Talking tails : quantifying the development of tail biting in pigs [PDF]

open access: yes, 2010
Tail biting is an adverse behaviour characterised by manipulation of a pig’s tail by another pig resulting in tail damage and a possible tail biting outbreak. Tail biting is a common problem in the pig husbandry causing economic losses and reduced animal
Zonderland, J.J.
core  

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