Results 221 to 230 of about 667,209 (277)

Poly (ADP-Ribose) Polymerase 1 and 2 in B-Cell Lymphoma: Pathogenic Roles and Therapeutic Implications. [PDF]

Am J Pathol
Molina-Alvarez A, Sanchez-Gonzalez B, Colomo L, Yélamos J.   +3 more
europepmc   +1 more source

Recurrent patterns and prognostic factors based on CA-125 and RECIST progression in ovarian cancer patients treated with poly (ADP-ribose) polymerase inhibitors. [PDF]

J Ovarian Res
Zhang B, Lv W, Fu Z, Zhou Y, Du J, Yao Q, Qian Q, Bu H.   +7 more
europepmc   +1 more source

R2eGIN: Residual Reconstruction Enhanced Graph Isomorphism Network for Accurate Prediction of Poly (ADP-Ribose) Polymerase Inhibitors. [PDF]

Bioinform Biol Insights
Zonyfar C, Njimbouom SN, Mosalla S, Kim JD.   +3 more
europepmc   +1 more source

Versatile Modular Antibodies for Sensitive and Specific Detection of Poly-ADP-Ribose

Dauben H, Matić I.
europepmc   +1 more source

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Importance of Poly(ADP-Ribose) Glycohydrolase in the Control of Poly(ADP-Ribose) Metabolism

Experimental Cell Research, 2001
Poly(ADP-ribosyl)ation is a posttranslational modification that alters the functions of the acceptor proteins and is catalyzed by the poly(ADP-ribose) polymerase (PARP) family of enzymes. Following DNA damage, activated poly(ADP-ribose) polymerase-1 (PARP-1) catalyzes the elongation and branching of poly(ADP-ribose) (pADPr) covalently attached to ...
Laetitia Davidovic, Guy Poirier, Momchil Vodenicharov   +2 more
exaly   +3 more sources

Poly(etheno ADP-ribose) blocks poly(ADP-ribose) glycohydrolase activity

Biochemical and Biophysical Research Communications, 2007
Poly(ADP-ribose) is a biopolymer synthesized by poly(ADP-ribose) polymerases. Recent findings suggest the possibility for modulation of cellular functions including cell death and mitosis by poly(ADP-ribose). Derivatization of poly(ADP-ribose) may be useful for investigating the effects of poly(ADP-ribose) on various cellular processes.
Masatoshi Watanabe
exaly   +3 more sources

Poly(ADP-ribose): Historical perspective

Molecular and Cellular Biochemistry, 1994
The early historical background of the discovery of poly(ADP-ribose) and the following development of science on poly(ADP-ribose) are reviewed. Fundamental knowledge on the natures of poly(ADP-ribose), poly(ADP-ribose) polymerase and enzymes degrading poly(ADP-ribose) are summarized with brief description on the methodology for their purification and ...
Masanao Miwa
exaly   +3 more sources

Poly(ADP-ribose) signaling in cell death

Molecular Aspects of Medicine, 2013
Poly(ADP-ribosyl)ation (PARylation) is a reversible protein modification carried out by the concerted actions of poly(ADP-ribose) polymerase (PARP) enzymes and poly(ADP-ribose) (PAR) decomposing enzymes such as PAR glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3).
Agnieszka Robaszkiewicz, László Virág
exaly   +4 more sources

Poly(ADP‐ribose) and carcinogenesis

Genes, Chromosomes and Cancer, 2003
AbstractPoly(ADP‐ribose) and poly(ADP‐ribose) polymerase (PARP) were discovered about 40 years ago, but their significance was not well elucidated until recently. In the early stage of the history of PARP, the presence of antibodies in the sera of human patients with lupus erythematosus indicated its natural occurrence.
Mitsuko, Masutani, Hitoshi, Nakagama, Takashi, Sugimura   +2 more
openaire   +2 more sources

The Use of Biotinylated Poly(ADP-Ribose) for Studies on Poly(ADP-Ribose)-Protein Interaction

Analytical Biochemistry, 1994
Poly(ADP-ribose) is routinely detected by the use of radioactive polymers formed from labeled substrates. In this report a simple and time-saving method for the biotinylation and the detection of poly(ADP-ribose) on blots is described. The polymer modified by light-induced reaction with photobiotin was colorimetrically detected and quantified, using ...
F M, Narendja, G, Sauermann
openaire   +2 more sources