Results 221 to 230 of about 98,022 (279)

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

British Journal of Pharmacology, Volume 183, Issue 9, Page 1747-1778, May 2026.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska, Marta Baranowska‐Kuczko, Hanna Kozłowska   +2 more
wiley   +1 more source

A Knockout of Poly(ADP-Ribose) Polymerase 1 in a Human Cell Line: An Influence on Base Excision Repair Reactions in Cellular Extracts. [PDF]

Cells
Khodyreva SN, Ilina ES, Dyrkheeva NS, Kochetkova AS, Yamskikh AA, Maltseva EA, Malakhova AA, Medvedev SP, Zakian SM, Lavrik OI.   +9 more
europepmc   +1 more source

Genomic Profiling in Localized Prostate Cancer: Associations With Biochemical Recurrence and Response to Salvage Radiotherapy

Cancer Science, Volume 117, Issue 5, Page 1469-1480, May 2026.
Early screening for somatic alterations in localized prostate cancer could help predict biochemical recurrence risk and optimize salvage therapy selection. ABSTRACT The clinical significance of comprehensive genomic profiling (CGP) has been established in metastatic castration‐resistant prostate cancer (PC).
Kenji Zennami, Tetsuya Takimoto, Takuhisa Nukaya, Makoto Sumitomo, Mayu Takeda, Eiji Sugihara, Hideyuki Saya, Ryoichi Shiroki   +7 more
wiley   +1 more source

Type III secretion system effector YfiD inhibits the activation of host poly(ADP-ribose) polymerase-1 to promote bacterial infection. [PDF]

Commun Biol
Zhou M, Liu Y, Zhang Y, Ma Y, Zhang Y, Choi SH, Shao S, Wang Q.   +7 more
europepmc   +1 more source

A novel glucose beta‐hydroxybutyrate combination improves hypoglycaemia recovery and patient‐reported outcomes in type 1 diabetes

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3590-3597, May 2026.
Abstract Aims Hypoglycaemia remains a major barrier to optimal diabetes management. Current treatments based on simple sugars have limitations, including rapid glucose fluctuations and persistent neuroglycopenic symptoms. We investigated FLO23011, a novel multi‐substrate energy formulation containing glucose and beta‐hydroxybutyrate, as a superior ...
D. Russell‐Jones, V. Smout, S. Roy, G. Myers, R. Littlewood, F. Shojaee‐Moradie   +5 more
wiley   +1 more source

Poly(ADP-ribose) polymerase 1 in genome-wide expression control in Drosophila. [PDF]

Sci Rep, 2020
Bordet G, Lodhi N, Guo D, Kossenkov A, Tulin AV.   +4 more
europepmc   +1 more source

Clinicopathological Status and Prognostic Factors of Recurrent Epithelial Ovarian Cancer in Japan: Retrospective Survey of JSOG Committee on Gynecologic Oncology

Journal of Obstetrics and Gynaecology Research, Volume 52, Issue 5, May 2026.
ABSTRACT Aim Despite advancements in maintenance therapies, recurrent epithelial ovarian cancer remains a clinical challenge with varying outcomes. This study aimed to evaluate the clinicopathological status and prognostic factors of patients with recurrent epithelial ovarian cancer.
Yoh Watanabe, Tsukasa Baba, Shu Soeda, Hideki Tokunaga, Wataru Yamagami, Hiroyuki Nomura, Yoichi Kobayashi, Kei Kawana, Kiyoshi Yoshino, Yoshihito Yokoyama, Hirotaka Nishi, Hiroaki Kobayashi, Yukiko Matsuzawa, Shunsuke Oyamada, Satoru Takahashi, Satoru Nagase   +15 more
wiley   +1 more source

SCL15 Promotes Seed Longevity Acquisition in Arabidopsis thaliana by Enhancing Antioxidant and Repair Mechanisms During Maturation

Physiologia Plantarum, Volume 178, Issue 3, May/June 2026.
ABSTRACT To ensure seed longevity and successful germination, orthodox seeds acquire protective and repair mechanisms during the late stage of seed development to counteract the detrimental effects of desiccation and subsequent rehydration, processes often associated with oxidative stress.
Ming‐Jun Gao, Cathy Coutu, Qi Chen, Myrtle Harrington, Rong Zhou, Dwayne Hegedus   +5 more
wiley   +1 more source

Poly(ADP-ribose) polymerases as modulators of mitochondrial activity [PDF]

, 2019
Bai, Péter, Fodor, Tamás, Liaudet, Lucas, Nagy, Lilla Nikoletta, Pacher, Pál   +4 more
core   +1 more source

The Role of Histone Modifications in Plant Priming and Their Analysis by Chromatin Immunoprecipitation

Physiologia Plantarum, Volume 178, Issue 3, May/June 2026.
ABSTRACT Plants are frequently exposed to adverse conditions. Priming, also known as acclimation or hardening, induces stress memory and prepares plants for future challenges by activating defense and protective mechanisms. For this reason, priming is an effective means to maintain plant yield in the face of climate change. Memory behind the priming is
Aslihan Temel, Nihal Gören‐Sağlam
wiley   +1 more source