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Hemostatic toxicity of poly I-C
Toxicology and Applied Pharmacology, 1972Abstract Intravenous therapy in beagles with Poly I-C resulted in a dose-related toxicity. In animals receiving 3.0 mg/kg, the clinical and pathological evidence indicated that disseminated intravascular coagulation (DIC) led directly to their death. In animals receiving 0.3 mg/kg evidence for DIC was present both by clinical and pathological studies;
H R, Gralnick +3 more
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Physical and Enzymatic Studies on Poly d(I–C).Poly d(I–C), an Unusual Double-helical DNA
Nature, 1970X-ray diffraction and circular dichroism studies indicate that poly d(I–C).poly d(I–C) exists in a new polynucleotide configuration—an eight-fold helix, possibly left-handed.
Y, Mitsui +6 more
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Poly I : C in herpetic keratitis in rabbits
Experimental Eye Research, 1974Abstract Herpetic keratoconjunctivitis, induced in rabbit eyes, was experimentally treated with poly-inosinic and poly-cytidilic acid (poly I : C), idoxuridine (IDU) and a combination thereof. It appeared that IDU 0·1% four times daily and poly I:C 1 mg/ml twice daily combined are more effective than either IDU four times daily or poly I:C twice or ...
J A, Oosterhuis +3 more
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Macromolecules, 2005
The spherulitic growth of poly(ethylene oxide) (PEO) was found to continue in the spherulites of poly(butylene adipate-co-butylene succinate) (PBAS) in the simultaneous spherulitic growth process of the two components in PBAS/PEO blends. This phenomenon, namely the formation of interpenetrating spherulites (IPS), was analyzed on the basis of ...
Takayuki Ikehara +2 more
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The spherulitic growth of poly(ethylene oxide) (PEO) was found to continue in the spherulites of poly(butylene adipate-co-butylene succinate) (PBAS) in the simultaneous spherulitic growth process of the two components in PBAS/PEO blends. This phenomenon, namely the formation of interpenetrating spherulites (IPS), was analyzed on the basis of ...
Takayuki Ikehara +2 more
openaire +1 more source
Biomaterials Science, 2023
FP-NPs inhibit metastatic melanoma by promoting MDSC differentiation to M1 macrophages.
Gaochuan Fang +7 more
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FP-NPs inhibit metastatic melanoma by promoting MDSC differentiation to M1 macrophages.
Gaochuan Fang +7 more
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Macromolecules, 2003
The deformation properties under a tensile load of poly(e-caprolactone) (PCL) were compared to those of PCL/PVME and PCL/SAN mixtures. The critical strains at the end of the Hooke range (point A) and at the yield point (point B) remain unchanged. The critical strain marking the beginning of a disintegration of the blocklike crystallites and a fibril ...
Y. Men, G. Strobl
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The deformation properties under a tensile load of poly(e-caprolactone) (PCL) were compared to those of PCL/PVME and PCL/SAN mixtures. The critical strains at the end of the Hooke range (point A) and at the yield point (point B) remain unchanged. The critical strain marking the beginning of a disintegration of the blocklike crystallites and a fibril ...
Y. Men, G. Strobl
openaire +1 more source
Journal of Food Biochemistry, 2022
Pectin oligosaccharides (POS) are pectin-derived prebiotics that exerts anti-inflammatory effects on the host and stimulates an innate immune response. The role of POS in protective immunity against viral infections is not very obvious. Therefore, the prophylactic effect of POS in the mouse model induced by Poly I: C mimicking viral infection was ...
Nidhi Sori +3 more
openaire +2 more sources
Pectin oligosaccharides (POS) are pectin-derived prebiotics that exerts anti-inflammatory effects on the host and stimulates an innate immune response. The role of POS in protective immunity against viral infections is not very obvious. Therefore, the prophylactic effect of POS in the mouse model induced by Poly I: C mimicking viral infection was ...
Nidhi Sori +3 more
openaire +2 more sources

