Results 261 to 270 of about 546,465 (315)

Hemostatic toxicity of poly I-C

Toxicology and Applied Pharmacology, 1972
Abstract Intravenous therapy in beagles with Poly I-C resulted in a dose-related toxicity. In animals receiving 3.0 mg/kg, the clinical and pathological evidence indicated that disseminated intravascular coagulation (DIC) led directly to their death. In animals receiving 0.3 mg/kg evidence for DIC was present both by clinical and pathological studies;
H R, Gralnick   +3 more
openaire   +2 more sources

Physical and Enzymatic Studies on Poly d(I–C).Poly d(I–C), an Unusual Double-helical DNA

Nature, 1970
X-ray diffraction and circular dichroism studies indicate that poly d(I–C).poly d(I–C) exists in a new polynucleotide configuration—an eight-fold helix, possibly left-handed.
Y, Mitsui   +6 more
openaire   +2 more sources

Poly I : C in herpetic keratitis in rabbits

Experimental Eye Research, 1974
Abstract Herpetic keratoconjunctivitis, induced in rabbit eyes, was experimentally treated with poly-inosinic and poly-cytidilic acid (poly I : C), idoxuridine (IDU) and a combination thereof. It appeared that IDU 0·1% four times daily and poly I:C 1 mg/ml twice daily combined are more effective than either IDU four times daily or poly I:C twice or ...
J A, Oosterhuis   +3 more
openaire   +2 more sources

Penetrating Spherulitic Growth in Poly(butylene adipate-co-butylene succinate)/Poly(ethylene oxide) Blends

Macromolecules, 2005
The spherulitic growth of poly(ethylene oxide) (PEO) was found to continue in the spherulites of poly(butylene adipate-co-butylene succinate) (PBAS) in the simultaneous spherulitic growth process of the two components in PBAS/PEO blends. This phenomenon, namely the formation of interpenetrating spherulites (IPS), was analyzed on the basis of ...
Takayuki Ikehara   +2 more
openaire   +1 more source

Immunologically active ferumoxytol-poly(I : C) nanomaterials inhibit metastatic melanoma by regulating myeloid-derived suppressor cell differentiation

Biomaterials Science, 2023
FP-NPs inhibit metastatic melanoma by promoting MDSC differentiation to M1 macrophages.
Gaochuan Fang   +7 more
openaire   +2 more sources

Critical Strains in Poly(ε-caprolactone) and Blends with Poly(vinyl methyl ether) and Poly(styrene-co-acrylonitrile)

Macromolecules, 2003
The deformation properties under a tensile load of poly(e-caprolactone) (PCL) were compared to those of PCL/PVME and PCL/SAN mixtures. The critical strains at the end of the Hooke range (point A) and at the yield point (point B) remain unchanged. The critical strain marking the beginning of a disintegration of the blocklike crystallites and a fibril ...
Y. Men, G. Strobl
openaire   +1 more source

Prophylactic effect of pectic oligosaccharides against poly I: C‐ induced virus‐like infection in BALB/c mice

Journal of Food Biochemistry, 2022
Pectin oligosaccharides (POS) are pectin-derived prebiotics that exerts anti-inflammatory effects on the host and stimulates an innate immune response. The role of POS in protective immunity against viral infections is not very obvious. Therefore, the prophylactic effect of POS in the mouse model induced by Poly I: C mimicking viral infection was ...
Nidhi Sori   +3 more
openaire   +2 more sources

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