Results 121 to 130 of about 58,232 (298)

Polyamine ????????? ???????????? ????????? ??????????????? ??????

open access: yes, 1998
Polyamine was synthesized for the drinking water treatment. Polyamine was produced by the two step polycondensation of dimethytamine(DMA) and epichlorohydrin(EPI) and its properties were characterized.
Shin, Myung-Chul   +4 more
core  

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

open access: yesThe FEBS Journal, EarlyView.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo   +4 more
wiley   +1 more source

Polyamine Drug Discovery: Synthetic Approaches to Therapeutic Modulators of Polyamine Metabolism

open access: yes, 2011
Numerous synthetic compounds have been described that either act as inhibitors of enzymes involved in polyamine metabolism or otherwise modulate these pathways.
Patrick M. Woster
core   +1 more source

S‐Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea

open access: yesThe FEBS Journal, EarlyView.
S‐Adenosyl‐l‐methionine (SAM) is a vital enzyme cofactor. Epimerisation at the sulfonium centre of biologically active (SS,SCα)‐SAM is driven by heat, yielding biologically inactive (RS,SCα)‐SAM. Here, two novel archaeal SAM hydrolases from the thermophilic Sulfolobus acidocaldarius and the halophilic Haloferax volcanii are shown to cleave (RS,SCα)‐SAM.
Agnes Bartels   +7 more
wiley   +1 more source

Genomic variation drives plant flavor diversification

open access: yesJournal of Integrative Plant Biology, EarlyView.
This review explains how genomic variation shapes plant flavor by altering the biosynthetic and regulatory pathways of key attributes like sweetness, acidity, bitterness, piquancy, astringency, and aroma. It also discusses how multi‐omics, AI‐assisted breeding, and gene editing can translate this knowledge into plants with improved flavor, nutrition ...
Huimin Hu   +5 more
wiley   +1 more source

Polyamine Metabolism Promotes the Progression of Thyroid Carcinoma by Regulating the Immune Phenotype of Tumor Associated Macrophages

open access: yesSmart Medicine
Polyamine metabolism is a key regulator of cellular proliferation and immune modulation, and its dysregulation is implicated in multiple carcinoma pathogenesis.
Haoran Ding   +8 more
doaj   +1 more source

Polyamine-Dependent Early Cellular Signals and Cell Proliferation

open access: yes, 2006
When a resting cell is awakened to enter the cell cycle by mitogenic stimulation, a complex molecular machinery involving positive and negative regulation of cell-cycle progression is initiated. Part of the machinery is quite well-known.
Oredsson, Stina,   +2 more
core   +1 more source

Physicochemical Quality and Chemical Safety of Commercial Wet Cat Food: Composition, Oxidation, Biogenic Amines, and Trace Elements

open access: yesJournal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT This study investigated the physicochemical characteristics and chemical safety of commercial wet cat foods marketed in Brazil. Twenty products labeled as beef, chicken and fish flavors were analyzed for proximate composition, pH, lipid and protein oxidation, biogenic amines, and essential and potentially toxic trace elements.
Marina Teixeira de Vries Mársico   +6 more
wiley   +1 more source

Duplication and diversification of the spermidine/spermine N1-acetyltransferase 1 genes in zebrafish.

open access: yesPLoS ONE, 2013
Spermidine/spermine N(1)-acetyltransferase 1 (Ssat1) is a key enzyme in the polyamine interconversion pathway, which maintains polyamine homeostasis.
Yi-Chin Lien   +4 more
doaj   +1 more source

Structure-activity investigations of polyamine-anthracene conjugates and their uptake via the polyamine transporter

open access: yes, 2007
A series of polyamine conjugates were synthesized and evaluated for their ability to target the polyamine transporter (PAT) in two Chinese hamster ovary (CHO) cell lines (PAT-active CHO and PAT-inactive CHOMG).

core   +1 more source

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