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Regulation of polyamine transport by polyamines and polyamine analogs

Journal of Cellular Physiology, 1993
AbstractRegulation of polyamine transport in murine L1210 leukemia cells was characterized in order to better understand its relationship to specific intracellular polyamines and their analogs and to quantitate the sensitivity by which it is controlled.
D L, Kramer   +5 more
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Chromatin remodeling by polyamines and polyamine analogs

Amino Acids, 2013
Natural polyamines are involved in many molecular processes, including maintenance of DNA structure and RNA processing and translation. Our aim here is to present an overview of the literature concerning the significance of polyamines in the modulation of chromatin arrangement and the transcriptional regulation of gene expression.
PASINI, ALICE   +2 more
openaire   +3 more sources

Polyamine Alkaloids

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Bienz, Stefan   +3 more
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Polyamines

Journal of Chromatography B: Biomedical Sciences and Applications, 1982
Putrescine, spermidine, spermine and their derivatives are considered to be potential markers of certain diseases. Routine methods have, therefore, been developed in the course of the last decade. Several automated liquid chromatographic and gas chromatographic methods are presently at our disposal, which meet the practical requirements of sensitivity ...
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Polyamines in trypanosomatids

Journal of Bacteriology, 1977
Polyamines were determined by n-butanol extraction and thin-layer chromatography in four trypanosomatids: Trypanosoma brucei (rat infection) and cultures of Crithidia fasciculata, Leptomonas sp., and Trypanosoma mega. All had putrescine and spermidine but no detectable spermine.
C J, Bacchi, G Y, Lipschik, H C, Nathan
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Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase [PDF]

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2019
Fourteen polyamine analogues, asymmetric or symmetric substituted spermine (1–9) or methoctramine (10–14) analogues, were evaluated as potential inhibitors or substrates of two enzymes of the polyamine catabolic pathway, spermine oxidase (SMOX) and ...
Maria Luisa Di Paolo   +2 more
exaly   +2 more sources

Polyamines

Molecular Biotechnology, 1999
The polyamines spermine, spermidine, and putrescine are small organic molecules one or more of which are present in all living organisms. Many natural products contain polyamine residues. Polyamines are synthesized by a highly regulated pathway from arginine or ornithine and also can be transported in and out of cells.
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On aliphatic polyamines IV

Recueil des Travaux Chimiques des Pays-Bas, 1936
AbstractThe high boiling amines, obtained by the interaction of 1: 3‐dibromo‐propane and 1: 2‐diamino‐ethane hydrate, have been investigated. The lower terms contain straight chains of dimethylene and trimethylene groups separated by nitrogen atoms but in the higher boiling fractions cyclic amines are present.
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Chromatography of polyamines

Journal of Chromatography A, 1965
The separation of polyethylene polyamines by various forms of chromatography has been studied. Ethylenediamine is easily separated from the higher polyamines by thin-layer chromatography and by ion-exchange chromatography. Diethylenetriamine, triethylenetetramine and tetraethylenepentamine can be separated by gas-liquid chromatography on Teflon powder ...
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